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The effects of melatonin on the physical properties of bones and egg shells in the laying hen.

Taylor AC, Horvat-Gordon M, Moore A, Bartell PA - PLoS ONE (2013)

Bottom Line: Hens treated with a high concentration of melatonin showed significant strengthening in their femur and tibia, as measured by maximum force sustained and breaking force, compared to controls.Egg weights from hens treated with melatonin were significantly greater than those from hens that were not treated with melatonin.Conversely, egg shell mass of hens treated with melatonin was significantly lower than those of hens not treated with melatonin.

View Article: PubMed Central - PubMed

Affiliation: Department of Animal Science, The Pennsylvania State University, University Park, Pennsylvania, USA.

ABSTRACT
Laying hens often experience unbalanced calcium utilization which can cause deficiencies in bone and egg mineralization. Because melatonin has been shown to affect bone mineralization in other animals, we examined whether treating hens with melatonin would affect eggshell thickness and improve skeletal performance, thereby reducing skeletal and egg shell defects. Birds were given a diet containing either low (30 µg/kg), medium (300 µg/kg), or high (3 mg/kg) concentrations of melatonin, or control feed through approximately one laying cycle. We examined the weight, length, and strength of egg, femur, tibia, and keel. Hens treated with a high concentration of melatonin showed significant strengthening in their femur and tibia, as measured by maximum force sustained and breaking force, compared to controls. Egg weights from hens treated with melatonin were significantly greater than those from hens that were not treated with melatonin. Conversely, egg shell mass of hens treated with melatonin was significantly lower than those of hens not treated with melatonin. Our data suggest that melatonin may affect the allocation of calcium to bone at the expense of egg shell mineralization.

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Related in: MedlinePlus

Melatonin levels in plasma from control (A), low melatonin (B), medium melatonin (C) and high melatonin (D) treated birds.Melatonin levels were rhythmic in control (p<0.02), low (p<0.02) and medium birds (p<0.05), but non-rhythmic after high melatonin treatment.
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pone-0055663-g011: Melatonin levels in plasma from control (A), low melatonin (B), medium melatonin (C) and high melatonin (D) treated birds.Melatonin levels were rhythmic in control (p<0.02), low (p<0.02) and medium birds (p<0.05), but non-rhythmic after high melatonin treatment.

Mentions: Analysis of melatonin in blood plasma showed melatonin treatment raised plasma levels of melatonin in all birds treated with melatonin (Fig. 11). Melatonin levels were raised during the daytime, but were still rhythmic across the day in low and medium melatonin treated birds (p<0.02). The levels of melatonin in birds from the high treatment group were arrhythmic, with higher levels occurring during the daytime.


The effects of melatonin on the physical properties of bones and egg shells in the laying hen.

Taylor AC, Horvat-Gordon M, Moore A, Bartell PA - PLoS ONE (2013)

Melatonin levels in plasma from control (A), low melatonin (B), medium melatonin (C) and high melatonin (D) treated birds.Melatonin levels were rhythmic in control (p<0.02), low (p<0.02) and medium birds (p<0.05), but non-rhythmic after high melatonin treatment.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3585294&req=5

pone-0055663-g011: Melatonin levels in plasma from control (A), low melatonin (B), medium melatonin (C) and high melatonin (D) treated birds.Melatonin levels were rhythmic in control (p<0.02), low (p<0.02) and medium birds (p<0.05), but non-rhythmic after high melatonin treatment.
Mentions: Analysis of melatonin in blood plasma showed melatonin treatment raised plasma levels of melatonin in all birds treated with melatonin (Fig. 11). Melatonin levels were raised during the daytime, but were still rhythmic across the day in low and medium melatonin treated birds (p<0.02). The levels of melatonin in birds from the high treatment group were arrhythmic, with higher levels occurring during the daytime.

Bottom Line: Hens treated with a high concentration of melatonin showed significant strengthening in their femur and tibia, as measured by maximum force sustained and breaking force, compared to controls.Egg weights from hens treated with melatonin were significantly greater than those from hens that were not treated with melatonin.Conversely, egg shell mass of hens treated with melatonin was significantly lower than those of hens not treated with melatonin.

View Article: PubMed Central - PubMed

Affiliation: Department of Animal Science, The Pennsylvania State University, University Park, Pennsylvania, USA.

ABSTRACT
Laying hens often experience unbalanced calcium utilization which can cause deficiencies in bone and egg mineralization. Because melatonin has been shown to affect bone mineralization in other animals, we examined whether treating hens with melatonin would affect eggshell thickness and improve skeletal performance, thereby reducing skeletal and egg shell defects. Birds were given a diet containing either low (30 µg/kg), medium (300 µg/kg), or high (3 mg/kg) concentrations of melatonin, or control feed through approximately one laying cycle. We examined the weight, length, and strength of egg, femur, tibia, and keel. Hens treated with a high concentration of melatonin showed significant strengthening in their femur and tibia, as measured by maximum force sustained and breaking force, compared to controls. Egg weights from hens treated with melatonin were significantly greater than those from hens that were not treated with melatonin. Conversely, egg shell mass of hens treated with melatonin was significantly lower than those of hens not treated with melatonin. Our data suggest that melatonin may affect the allocation of calcium to bone at the expense of egg shell mineralization.

Show MeSH
Related in: MedlinePlus