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Short-term role of the dietary total antioxidant capacity in two hypocaloric regimes on obese with metabolic syndrome symptoms: the RESMENA randomized controlled trial.

Lopez-Legarrea P, de la Iglesia R, Abete I, Bondia-Pons I, Navas-Carretero S, Forga L, Martinez JA, Zulet MA - Nutr Metab (Lond) (2013)

Bottom Line: Dietary TAC was the component which showed the major influence on body weight (p = 0.034), body mass index (p = 0.026), waist circumference (p = 0.083) and fat mass (p = 0.015) reductions.Transaminases (ALT and AST) levels (p = 0.062 and p = 0.004, respectively) were associated with lower TAC values.RESMENA diet was as effective as AHA pattern for reducing MetS features.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Nutrition, Food Science and Physiology, University of Navarra, Irunlarrea rd 1, Pamplona, 31008, Spain. jalfmtz@unav.es.

ABSTRACT

Background: Dietary strategies seem to be the most prescribed therapy in order to counteract obesity regarding not only calorie restriction, but also bioactive ingredients and the composition of the consumed foods. Dietary total antioxidant capacity (TAC) is gaining importance in order to assess the quality of the diet.

Methods: Ninety-six obese adults presenting metabolic syndrome (MetS) symptoms completed an 8-week intervention trial to evaluate the effects of a novel dietary program with changes in the nutrient distribution and meal frequency and to compare it with a dietary pattern based on the American Heart Association (AHA) guidelines.Anthropometric and biochemical parameters were assessed at baseline and at the endpoint of the study, in addition to 48-hours food dietary records.

Results: Both diets equally (p > 0.05) improved MetS manifestations. Dietary TAC was the component which showed the major influence on body weight (p = 0.034), body mass index (p = 0.026), waist circumference (p = 0.083) and fat mass (p = 0.015) reductions. Transaminases (ALT and AST) levels (p = 0.062 and p = 0.004, respectively) were associated with lower TAC values.

Conclusion: RESMENA diet was as effective as AHA pattern for reducing MetS features. Dietary TAC was the most contributing factor involved in body weight and obesity related markers reduction.

Trial registration: http://www.clinicaltrials.gov; NCT01087086.

No MeSH data available.


Related in: MedlinePlus

Changes on anthropometric and biochemical selected parameters regarding gender, male (n = 51) or female (n = 45). HDL-c: High Density Lipoprotein-cholesterol; ALT: Alanine aminotransferase. p -values comparing the differences between male and female groups.
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Figure 3: Changes on anthropometric and biochemical selected parameters regarding gender, male (n = 51) or female (n = 45). HDL-c: High Density Lipoprotein-cholesterol; ALT: Alanine aminotransferase. p -values comparing the differences between male and female groups.

Mentions: As expected, gender variation influenced anthropometrical and biochemical parameters changes (Table 5). Body weight loss was significantly higher in males than in females (p = 0.008), as well as fat mass reduction (p = 0.042) (Figure 3). Interestingly, men showed a statistically significant decrease of insulin blood levels (p = 0.020). Concurrently, ALT values were significantly reduced in men, while we did not found any changes in this marker in females group (Figure 3). Regarding dietary TAC influence, differences concerning gender were found. Women with higher TAC levels, showed a significantly greater reduction of body weight (p = 0.019), BMI (p = 0.028) and fat mass (p = 0.007), while there were not any variable differences between high or low TAC in the male group.


Short-term role of the dietary total antioxidant capacity in two hypocaloric regimes on obese with metabolic syndrome symptoms: the RESMENA randomized controlled trial.

Lopez-Legarrea P, de la Iglesia R, Abete I, Bondia-Pons I, Navas-Carretero S, Forga L, Martinez JA, Zulet MA - Nutr Metab (Lond) (2013)

Changes on anthropometric and biochemical selected parameters regarding gender, male (n = 51) or female (n = 45). HDL-c: High Density Lipoprotein-cholesterol; ALT: Alanine aminotransferase. p -values comparing the differences between male and female groups.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3584921&req=5

Figure 3: Changes on anthropometric and biochemical selected parameters regarding gender, male (n = 51) or female (n = 45). HDL-c: High Density Lipoprotein-cholesterol; ALT: Alanine aminotransferase. p -values comparing the differences between male and female groups.
Mentions: As expected, gender variation influenced anthropometrical and biochemical parameters changes (Table 5). Body weight loss was significantly higher in males than in females (p = 0.008), as well as fat mass reduction (p = 0.042) (Figure 3). Interestingly, men showed a statistically significant decrease of insulin blood levels (p = 0.020). Concurrently, ALT values were significantly reduced in men, while we did not found any changes in this marker in females group (Figure 3). Regarding dietary TAC influence, differences concerning gender were found. Women with higher TAC levels, showed a significantly greater reduction of body weight (p = 0.019), BMI (p = 0.028) and fat mass (p = 0.007), while there were not any variable differences between high or low TAC in the male group.

Bottom Line: Dietary TAC was the component which showed the major influence on body weight (p = 0.034), body mass index (p = 0.026), waist circumference (p = 0.083) and fat mass (p = 0.015) reductions.Transaminases (ALT and AST) levels (p = 0.062 and p = 0.004, respectively) were associated with lower TAC values.RESMENA diet was as effective as AHA pattern for reducing MetS features.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Nutrition, Food Science and Physiology, University of Navarra, Irunlarrea rd 1, Pamplona, 31008, Spain. jalfmtz@unav.es.

ABSTRACT

Background: Dietary strategies seem to be the most prescribed therapy in order to counteract obesity regarding not only calorie restriction, but also bioactive ingredients and the composition of the consumed foods. Dietary total antioxidant capacity (TAC) is gaining importance in order to assess the quality of the diet.

Methods: Ninety-six obese adults presenting metabolic syndrome (MetS) symptoms completed an 8-week intervention trial to evaluate the effects of a novel dietary program with changes in the nutrient distribution and meal frequency and to compare it with a dietary pattern based on the American Heart Association (AHA) guidelines.Anthropometric and biochemical parameters were assessed at baseline and at the endpoint of the study, in addition to 48-hours food dietary records.

Results: Both diets equally (p > 0.05) improved MetS manifestations. Dietary TAC was the component which showed the major influence on body weight (p = 0.034), body mass index (p = 0.026), waist circumference (p = 0.083) and fat mass (p = 0.015) reductions. Transaminases (ALT and AST) levels (p = 0.062 and p = 0.004, respectively) were associated with lower TAC values.

Conclusion: RESMENA diet was as effective as AHA pattern for reducing MetS features. Dietary TAC was the most contributing factor involved in body weight and obesity related markers reduction.

Trial registration: http://www.clinicaltrials.gov; NCT01087086.

No MeSH data available.


Related in: MedlinePlus