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Imaging of multifocal liver lesions in children and adolescents.

Hegde SV, Dillman JR, Lopez MJ, Strouse PJ - Cancer Imaging (2013)

Bottom Line: Multifocal liver lesions are encountered regularly in children and adolescents.By knowing the specific ultrasonographic, computed tomographic, and magnetic resonance imaging (MRI) features of benign and malignant pediatric liver lesions as well as the particular clinical setting, radiologists can frequently narrow the differential diagnosis and sometimes offer a definitive diagnosis.The purpose of this review article is to illustrate the imaging findings of numerous benign and malignant causes of multifocal liver lesions in the pediatric population.

View Article: PubMed Central - PubMed

Affiliation: Section of Pediatric Radiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI, USA.

ABSTRACT
Multifocal liver lesions are encountered regularly in children and adolescents. By knowing the specific ultrasonographic, computed tomographic, and magnetic resonance imaging (MRI) features of benign and malignant pediatric liver lesions as well as the particular clinical setting, radiologists can frequently narrow the differential diagnosis and sometimes offer a definitive diagnosis. The purpose of this review article is to illustrate the imaging findings of numerous benign and malignant causes of multifocal liver lesions in the pediatric population.

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A 12-year-old girl with a history of chronic immunosuppression due to inflammatory bowel disease and primary hepatic large B-cell lymphoma. Axial postcontrast CT image reveals multiple predominantly low attenuation liver lesions, some of which contain central enhancement giving rise to a target appearance. The spleen is also enlarged.
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Figure 13: A 12-year-old girl with a history of chronic immunosuppression due to inflammatory bowel disease and primary hepatic large B-cell lymphoma. Axial postcontrast CT image reveals multiple predominantly low attenuation liver lesions, some of which contain central enhancement giving rise to a target appearance. The spleen is also enlarged.

Mentions: Although most hepatic involvement by lymphoma is secondary, primary lymphoma, usually non-Hodgkin lymphoma, arising from the liver may occur on rare occasions[32]. Primary hepatic lymphoma occurs with increased incidence in immunosuppressed individuals (Fig. 13), including as part of the spectrum of post-transplant lymphoproliferative disease[33].Figure 13


Imaging of multifocal liver lesions in children and adolescents.

Hegde SV, Dillman JR, Lopez MJ, Strouse PJ - Cancer Imaging (2013)

A 12-year-old girl with a history of chronic immunosuppression due to inflammatory bowel disease and primary hepatic large B-cell lymphoma. Axial postcontrast CT image reveals multiple predominantly low attenuation liver lesions, some of which contain central enhancement giving rise to a target appearance. The spleen is also enlarged.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3569672&req=5

Figure 13: A 12-year-old girl with a history of chronic immunosuppression due to inflammatory bowel disease and primary hepatic large B-cell lymphoma. Axial postcontrast CT image reveals multiple predominantly low attenuation liver lesions, some of which contain central enhancement giving rise to a target appearance. The spleen is also enlarged.
Mentions: Although most hepatic involvement by lymphoma is secondary, primary lymphoma, usually non-Hodgkin lymphoma, arising from the liver may occur on rare occasions[32]. Primary hepatic lymphoma occurs with increased incidence in immunosuppressed individuals (Fig. 13), including as part of the spectrum of post-transplant lymphoproliferative disease[33].Figure 13

Bottom Line: Multifocal liver lesions are encountered regularly in children and adolescents.By knowing the specific ultrasonographic, computed tomographic, and magnetic resonance imaging (MRI) features of benign and malignant pediatric liver lesions as well as the particular clinical setting, radiologists can frequently narrow the differential diagnosis and sometimes offer a definitive diagnosis.The purpose of this review article is to illustrate the imaging findings of numerous benign and malignant causes of multifocal liver lesions in the pediatric population.

View Article: PubMed Central - PubMed

Affiliation: Section of Pediatric Radiology, Department of Radiology, University of Michigan Health System, Ann Arbor, MI, USA.

ABSTRACT
Multifocal liver lesions are encountered regularly in children and adolescents. By knowing the specific ultrasonographic, computed tomographic, and magnetic resonance imaging (MRI) features of benign and malignant pediatric liver lesions as well as the particular clinical setting, radiologists can frequently narrow the differential diagnosis and sometimes offer a definitive diagnosis. The purpose of this review article is to illustrate the imaging findings of numerous benign and malignant causes of multifocal liver lesions in the pediatric population.

Show MeSH
Related in: MedlinePlus