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A rare case of primary infiltrating neuroendocrine carcinoma of the breast.

Nawawi O, Ying Goh K, Rahmat K - Iran J Radiol (2012)

Bottom Line: There are not many cases reported in the English literature since it was first documented in 1983.Reports on the imaging features, in particular the ultrasonographic features of this rare tumor are scarce.Herein, we report a case of aggressive primary infiltrating neuroendocrine carcinoma of the breast, masquerading as an inflammatory breast condition in a 22-year-old young lady, perhaps the youngest case ever reported in the English literature.

View Article: PubMed Central - PubMed

Affiliation: Department of Biomedical Imaging, University of Malaya Medical Center, Kuala Lumpur, Malaysia.

ABSTRACT
Primary neuroendocrine carcinoma of the breast is a very rare malignant tumor. There are not many cases reported in the English literature since it was first documented in 1983. Reports on the imaging features, in particular the ultrasonographic features of this rare tumor are scarce. Herein, we report a case of aggressive primary infiltrating neuroendocrine carcinoma of the breast, masquerading as an inflammatory breast condition in a 22-year-old young lady, perhaps the youngest case ever reported in the English literature. We discuss the imaging features and highlight the Doppler ultrasonographic findings of this rare breast carcinoma. This is the first documentation on Doppler ultrasonographic findings of primary neuroendocrine carcinoma of the breast in the literature.

No MeSH data available.


Related in: MedlinePlus

Axial T2 fat suppressed MR image at the level of T3 showing a paravertebral mass extending into the spinal canal causing spinal cord displacement and compression. The mass has also indented the posterior wall of the trachea (white arrow) and displacing the esophagus anteriorly (black arrow).
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fig490: Axial T2 fat suppressed MR image at the level of T3 showing a paravertebral mass extending into the spinal canal causing spinal cord displacement and compression. The mass has also indented the posterior wall of the trachea (white arrow) and displacing the esophagus anteriorly (black arrow).

Mentions: A combination of cisplatin and etoposide (100 mg/m2) neoadjuvant chemotherapy based on the protocol for small cell lung carcinoma was started immediately. Upon completion of the 4th cycle of chemotherapy, she developed bilateral lower limb weakness with urinary incontinence and sensory loss up to T4 level. Magnetic resonance imaging (MRI) of the spine (GE 1.5T) demonstrated metastases to the vertebral bodies of T2 to T4 with paraspinal and epidural soft tissue components that caused spinal canal stenosis and spinal cord compression at the T3 level. The paraspinal component was also indenting the posterior wall of the trachea and displacing the esophagus anteriorly (Figure 4). Emergency decompression laminectomy and debulking of the paraspinal tumor was performed. After the surgery, she regained sensation with slight improvement of the power of both lower limbs, but on the 9th post surgical day, she suddenly developed chest discomfort and soon went into cardio-circulatory collapse. Attempts to revive her failed. Clinically, she was suspected of having acute pulmonary embolism. Post mortem autopsy was not performed on her as family members did not agree.


A rare case of primary infiltrating neuroendocrine carcinoma of the breast.

Nawawi O, Ying Goh K, Rahmat K - Iran J Radiol (2012)

Axial T2 fat suppressed MR image at the level of T3 showing a paravertebral mass extending into the spinal canal causing spinal cord displacement and compression. The mass has also indented the posterior wall of the trachea (white arrow) and displacing the esophagus anteriorly (black arrow).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3569554&req=5

fig490: Axial T2 fat suppressed MR image at the level of T3 showing a paravertebral mass extending into the spinal canal causing spinal cord displacement and compression. The mass has also indented the posterior wall of the trachea (white arrow) and displacing the esophagus anteriorly (black arrow).
Mentions: A combination of cisplatin and etoposide (100 mg/m2) neoadjuvant chemotherapy based on the protocol for small cell lung carcinoma was started immediately. Upon completion of the 4th cycle of chemotherapy, she developed bilateral lower limb weakness with urinary incontinence and sensory loss up to T4 level. Magnetic resonance imaging (MRI) of the spine (GE 1.5T) demonstrated metastases to the vertebral bodies of T2 to T4 with paraspinal and epidural soft tissue components that caused spinal canal stenosis and spinal cord compression at the T3 level. The paraspinal component was also indenting the posterior wall of the trachea and displacing the esophagus anteriorly (Figure 4). Emergency decompression laminectomy and debulking of the paraspinal tumor was performed. After the surgery, she regained sensation with slight improvement of the power of both lower limbs, but on the 9th post surgical day, she suddenly developed chest discomfort and soon went into cardio-circulatory collapse. Attempts to revive her failed. Clinically, she was suspected of having acute pulmonary embolism. Post mortem autopsy was not performed on her as family members did not agree.

Bottom Line: There are not many cases reported in the English literature since it was first documented in 1983.Reports on the imaging features, in particular the ultrasonographic features of this rare tumor are scarce.Herein, we report a case of aggressive primary infiltrating neuroendocrine carcinoma of the breast, masquerading as an inflammatory breast condition in a 22-year-old young lady, perhaps the youngest case ever reported in the English literature.

View Article: PubMed Central - PubMed

Affiliation: Department of Biomedical Imaging, University of Malaya Medical Center, Kuala Lumpur, Malaysia.

ABSTRACT
Primary neuroendocrine carcinoma of the breast is a very rare malignant tumor. There are not many cases reported in the English literature since it was first documented in 1983. Reports on the imaging features, in particular the ultrasonographic features of this rare tumor are scarce. Herein, we report a case of aggressive primary infiltrating neuroendocrine carcinoma of the breast, masquerading as an inflammatory breast condition in a 22-year-old young lady, perhaps the youngest case ever reported in the English literature. We discuss the imaging features and highlight the Doppler ultrasonographic findings of this rare breast carcinoma. This is the first documentation on Doppler ultrasonographic findings of primary neuroendocrine carcinoma of the breast in the literature.

No MeSH data available.


Related in: MedlinePlus