Limits...
Correcting and interpreting the effect of cognitive therapy versus exposure in anxiety disorders.

Ebrahim S, Bance S - BMC Psychiatry (2012)

Bottom Line: These were incorrectly meta-analysed.For PTSD, the SMD (95% CI) for short-term outcomes was -0.13 (-0.36, 0.11) and 0.05 (-0.22, 0.32) for long-term outcomes.However, correcting the errors did not change the interpretation of the findings considerably.

View Article: PubMed Central - HTML - PubMed

ABSTRACT
Dr. Ougrin's evaluation of cognitive therapy versus exposure in anxiety disorders reported a standardised mean difference [SMD] (95% confidence interval [CI]) of 0.52 (0.37, 0.74) for short-term outcomes and 0.46 (0.29, 0.73) for long-term outcomes in social phobia, and 0.88 (0.69, 1.11) for short-term outcomes and 1.05 (0.80, 1.37) for long-term outcomes in posttraumatic stress disorder (PTSD). These were incorrectly meta-analysed. Upon re-analysis, we found that the correct SMD (95% CI) was -0.66 (-1.19, -0.14) for short-term outcomes and mean difference (95% CI) of -29.66 (-46.13, -13.19) on the Social Phobia subscale from the Social Phobia Anxiety Inventory for long-term outcomes in Social Phobia. For PTSD, the SMD (95% CI) for short-term outcomes was -0.13 (-0.36, 0.11) and 0.05 (-0.22, 0.32) for long-term outcomes. However, correcting the errors did not change the interpretation of the findings considerably.

Show MeSH

Related in: MedlinePlus

Corrected meta-analysis of Figure 8 in Ougrin (2011): the long-term efficacy of cognitive therapy versus exposure in Social Phobia.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3539997&req=5

Figure 2: Corrected meta-analysis of Figure 8 in Ougrin (2011): the long-term efficacy of cognitive therapy versus exposure in Social Phobia.

Mentions: Long-term outcomes for social phobia were also incorrectly pooled as an OR. We found that the corrected SMD (95% CI) was 0.46 (0.29, 0.73) for long-term outcomes. However, the SMD should only be used when pooling different assessments for the same outcome. If the same assessment is reported across trials, the mean difference (MD) is always preferred. Both Clark (2006) and Hofmann (2004)[2,4] reported social phobia subscale scores from the Social Phobia and Anxiety Inventory (SPAI)[5]. Thus, we calculated the MD (95% CI) as −29.66 (−46.13, -13.19) (Figure2).


Correcting and interpreting the effect of cognitive therapy versus exposure in anxiety disorders.

Ebrahim S, Bance S - BMC Psychiatry (2012)

Corrected meta-analysis of Figure 8 in Ougrin (2011): the long-term efficacy of cognitive therapy versus exposure in Social Phobia.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3539997&req=5

Figure 2: Corrected meta-analysis of Figure 8 in Ougrin (2011): the long-term efficacy of cognitive therapy versus exposure in Social Phobia.
Mentions: Long-term outcomes for social phobia were also incorrectly pooled as an OR. We found that the corrected SMD (95% CI) was 0.46 (0.29, 0.73) for long-term outcomes. However, the SMD should only be used when pooling different assessments for the same outcome. If the same assessment is reported across trials, the mean difference (MD) is always preferred. Both Clark (2006) and Hofmann (2004)[2,4] reported social phobia subscale scores from the Social Phobia and Anxiety Inventory (SPAI)[5]. Thus, we calculated the MD (95% CI) as −29.66 (−46.13, -13.19) (Figure2).

Bottom Line: These were incorrectly meta-analysed.For PTSD, the SMD (95% CI) for short-term outcomes was -0.13 (-0.36, 0.11) and 0.05 (-0.22, 0.32) for long-term outcomes.However, correcting the errors did not change the interpretation of the findings considerably.

View Article: PubMed Central - HTML - PubMed

ABSTRACT
Dr. Ougrin's evaluation of cognitive therapy versus exposure in anxiety disorders reported a standardised mean difference [SMD] (95% confidence interval [CI]) of 0.52 (0.37, 0.74) for short-term outcomes and 0.46 (0.29, 0.73) for long-term outcomes in social phobia, and 0.88 (0.69, 1.11) for short-term outcomes and 1.05 (0.80, 1.37) for long-term outcomes in posttraumatic stress disorder (PTSD). These were incorrectly meta-analysed. Upon re-analysis, we found that the correct SMD (95% CI) was -0.66 (-1.19, -0.14) for short-term outcomes and mean difference (95% CI) of -29.66 (-46.13, -13.19) on the Social Phobia subscale from the Social Phobia Anxiety Inventory for long-term outcomes in Social Phobia. For PTSD, the SMD (95% CI) for short-term outcomes was -0.13 (-0.36, 0.11) and 0.05 (-0.22, 0.32) for long-term outcomes. However, correcting the errors did not change the interpretation of the findings considerably.

Show MeSH
Related in: MedlinePlus