Limits...
Magnetic resonance spectroscopy--a non-invasive method in evaluating focal and diffuse central nervous system disease.

Scheau C, Preda EM, Popa GA, Ghergus AE, Capsa RA, Lupescu IG - J Med Life (2012)

Bottom Line: Magnetic Resonance Spectroscopy is a non-invasive method, which can be performed following a routine Magnetic Resonance investigation within the same examination, and can provide very useful molecular information related to the metabolism and function of the normal and pathological structures of the brain.Its role is increasing in the establishment of a clear diagnosis, in both focal and diffuse central nervous system diseases, and the tendency is to replace the histopathology test, in certain cases, with similar or sometimes better diagnostic accuracy.This paper summarizes the principle, method, and main clinical applications, standing as a guide to procedure performing and results interpretation.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Medical Imaging, Fundeni Clinical Institute, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. cristianscheau@gmail.com

ABSTRACT
Magnetic Resonance Spectroscopy is a non-invasive method, which can be performed following a routine Magnetic Resonance investigation within the same examination, and can provide very useful molecular information related to the metabolism and function of the normal and pathological structures of the brain. Its role is increasing in the establishment of a clear diagnosis, in both focal and diffuse central nervous system diseases, and the tendency is to replace the histopathology test, in certain cases, with similar or sometimes better diagnostic accuracy. This paper summarizes the principle, method, and main clinical applications, standing as a guide to procedure performing and results interpretation.

Show MeSH

Related in: MedlinePlus

Short TE spectrum with specific changes of hepatic encephalopathy = elevated Glx and decreased mI peaks. Patient showed mild to moderate clinical symptoms.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3539838&req=5

Figure 4: Short TE spectrum with specific changes of hepatic encephalopathy = elevated Glx and decreased mI peaks. Patient showed mild to moderate clinical symptoms.

Mentions: Diffuse anomalies. In this case, depending on the pathology studied, we should orient our region of interest depending on the areas which are predominantly involved in that particular pathology, for instance: the posterior cingulate gyri and inferior precunci for Alzheimer Disease [22], hippocampus for epilepsy [23], parietal white matter for hepatic encephalopathy [24] (Fig. 4)), or parietal grey and white matter for dementia [25], with specific metabolites variations.


Magnetic resonance spectroscopy--a non-invasive method in evaluating focal and diffuse central nervous system disease.

Scheau C, Preda EM, Popa GA, Ghergus AE, Capsa RA, Lupescu IG - J Med Life (2012)

Short TE spectrum with specific changes of hepatic encephalopathy = elevated Glx and decreased mI peaks. Patient showed mild to moderate clinical symptoms.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3539838&req=5

Figure 4: Short TE spectrum with specific changes of hepatic encephalopathy = elevated Glx and decreased mI peaks. Patient showed mild to moderate clinical symptoms.
Mentions: Diffuse anomalies. In this case, depending on the pathology studied, we should orient our region of interest depending on the areas which are predominantly involved in that particular pathology, for instance: the posterior cingulate gyri and inferior precunci for Alzheimer Disease [22], hippocampus for epilepsy [23], parietal white matter for hepatic encephalopathy [24] (Fig. 4)), or parietal grey and white matter for dementia [25], with specific metabolites variations.

Bottom Line: Magnetic Resonance Spectroscopy is a non-invasive method, which can be performed following a routine Magnetic Resonance investigation within the same examination, and can provide very useful molecular information related to the metabolism and function of the normal and pathological structures of the brain.Its role is increasing in the establishment of a clear diagnosis, in both focal and diffuse central nervous system diseases, and the tendency is to replace the histopathology test, in certain cases, with similar or sometimes better diagnostic accuracy.This paper summarizes the principle, method, and main clinical applications, standing as a guide to procedure performing and results interpretation.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Medical Imaging, Fundeni Clinical Institute, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. cristianscheau@gmail.com

ABSTRACT
Magnetic Resonance Spectroscopy is a non-invasive method, which can be performed following a routine Magnetic Resonance investigation within the same examination, and can provide very useful molecular information related to the metabolism and function of the normal and pathological structures of the brain. Its role is increasing in the establishment of a clear diagnosis, in both focal and diffuse central nervous system diseases, and the tendency is to replace the histopathology test, in certain cases, with similar or sometimes better diagnostic accuracy. This paper summarizes the principle, method, and main clinical applications, standing as a guide to procedure performing and results interpretation.

Show MeSH
Related in: MedlinePlus