Limits...
Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation.

Brydak-Godowska J, Szczepanik S, Ciszek M, Bialas D, Grzeszczyk M, Strzeleck D, Kecik D - Med. Sci. Monit. (2011)

Bottom Line: In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere.The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks.Retinal detachment was observed in both eyes.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland. joannabg@tlen.pl

ABSTRACT

Background: Acute retinal necrosis (ARN) is characterized by the triad of acute vitritis, peripheral necrotizing retinitis and vasculitis.

Case report: We report a case of 54-year-old woman with bilateral acute retinal necrosis associated with neuroinfection. Her past medical history included renal transplantation, hypertension and aortic stenosis. Observational case report: Diagnostic investigations included biochemical tests, lumbar puncture, eye ultrasonography and MRI of the brain. Anti-HSV IgG antibody titers were elevated in the blood and cerebrospinal fluid. In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere. The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks. Retinal detachment was observed in both eyes.

Conclusions: Acute retinal necrosis can be the single manifestation of herpes virus reactivation in patients after organ transplantation.

Show MeSH

Related in: MedlinePlus

Primary retinal detachment involving the entire retina in the right eye in ultrasound scan.
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3539611&req=5

f2-medscimonit-17-8-cs99: Primary retinal detachment involving the entire retina in the right eye in ultrasound scan.

Mentions: In September 2007 systemic acyclovir and itraconazole were discontinued due to deteriorating renal function. Visual acuity dramatically deteriorated in the right eye (the patient was just able to count fingers directly in front of the eye) and inflammation in the vitreous body increased to a degree precluding evaluation of the eye fundus. Ultrasound examination found retinal detachment in the right eye and the patient was referred for vitrectomy (Figure 2).


Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation.

Brydak-Godowska J, Szczepanik S, Ciszek M, Bialas D, Grzeszczyk M, Strzeleck D, Kecik D - Med. Sci. Monit. (2011)

Primary retinal detachment involving the entire retina in the right eye in ultrasound scan.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539611&req=5

f2-medscimonit-17-8-cs99: Primary retinal detachment involving the entire retina in the right eye in ultrasound scan.
Mentions: In September 2007 systemic acyclovir and itraconazole were discontinued due to deteriorating renal function. Visual acuity dramatically deteriorated in the right eye (the patient was just able to count fingers directly in front of the eye) and inflammation in the vitreous body increased to a degree precluding evaluation of the eye fundus. Ultrasound examination found retinal detachment in the right eye and the patient was referred for vitrectomy (Figure 2).

Bottom Line: In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere.The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks.Retinal detachment was observed in both eyes.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland. joannabg@tlen.pl

ABSTRACT

Background: Acute retinal necrosis (ARN) is characterized by the triad of acute vitritis, peripheral necrotizing retinitis and vasculitis.

Case report: We report a case of 54-year-old woman with bilateral acute retinal necrosis associated with neuroinfection. Her past medical history included renal transplantation, hypertension and aortic stenosis. Observational case report: Diagnostic investigations included biochemical tests, lumbar puncture, eye ultrasonography and MRI of the brain. Anti-HSV IgG antibody titers were elevated in the blood and cerebrospinal fluid. In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere. The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks. Retinal detachment was observed in both eyes.

Conclusions: Acute retinal necrosis can be the single manifestation of herpes virus reactivation in patients after organ transplantation.

Show MeSH
Related in: MedlinePlus