Limits...
Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation.

Brydak-Godowska J, Szczepanik S, Ciszek M, Bialas D, Grzeszczyk M, Strzeleck D, Kecik D - Med. Sci. Monit. (2011)

Bottom Line: In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere.The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks.Retinal detachment was observed in both eyes.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland. joannabg@tlen.pl

ABSTRACT

Background: Acute retinal necrosis (ARN) is characterized by the triad of acute vitritis, peripheral necrotizing retinitis and vasculitis.

Case report: We report a case of 54-year-old woman with bilateral acute retinal necrosis associated with neuroinfection. Her past medical history included renal transplantation, hypertension and aortic stenosis. Observational case report: Diagnostic investigations included biochemical tests, lumbar puncture, eye ultrasonography and MRI of the brain. Anti-HSV IgG antibody titers were elevated in the blood and cerebrospinal fluid. In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere. The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks. Retinal detachment was observed in both eyes.

Conclusions: Acute retinal necrosis can be the single manifestation of herpes virus reactivation in patients after organ transplantation.

Show MeSH

Related in: MedlinePlus

Peripheral focus of retinal necrosis in the course of healing.
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3539611&req=5

f1-medscimonit-17-8-cs99: Peripheral focus of retinal necrosis in the course of healing.

Mentions: Serological studies were performed for active CMV infection, and no early pp-65 CMV antigen was detected. Systemic treatment with oral Heviran (acyclovir sodium) 400 mg bid, Encorton (prednisone) 40 mg once daily, itraconazole 100 mg once daily and Aspirin 500 mg once daily and topical treatment of the right eye with dexamethasone 1%, tropicamide 1% and Naclof (diclofenac sodium) were prescribed. After the treatment the reaction in the vitreous body was reduced, foci of retinal inflammation in the periphery healed and visual acuity in the right eye improved (BCVA for distance was 0.7 and 0.5 for reading; Figure 1).


Bilateral acute retinal necrosis associated with neuroinfection in patient after renal transplantation.

Brydak-Godowska J, Szczepanik S, Ciszek M, Bialas D, Grzeszczyk M, Strzeleck D, Kecik D - Med. Sci. Monit. (2011)

Peripheral focus of retinal necrosis in the course of healing.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539611&req=5

f1-medscimonit-17-8-cs99: Peripheral focus of retinal necrosis in the course of healing.
Mentions: Serological studies were performed for active CMV infection, and no early pp-65 CMV antigen was detected. Systemic treatment with oral Heviran (acyclovir sodium) 400 mg bid, Encorton (prednisone) 40 mg once daily, itraconazole 100 mg once daily and Aspirin 500 mg once daily and topical treatment of the right eye with dexamethasone 1%, tropicamide 1% and Naclof (diclofenac sodium) were prescribed. After the treatment the reaction in the vitreous body was reduced, foci of retinal inflammation in the periphery healed and visual acuity in the right eye improved (BCVA for distance was 0.7 and 0.5 for reading; Figure 1).

Bottom Line: In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere.The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks.Retinal detachment was observed in both eyes.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland. joannabg@tlen.pl

ABSTRACT

Background: Acute retinal necrosis (ARN) is characterized by the triad of acute vitritis, peripheral necrotizing retinitis and vasculitis.

Case report: We report a case of 54-year-old woman with bilateral acute retinal necrosis associated with neuroinfection. Her past medical history included renal transplantation, hypertension and aortic stenosis. Observational case report: Diagnostic investigations included biochemical tests, lumbar puncture, eye ultrasonography and MRI of the brain. Anti-HSV IgG antibody titers were elevated in the blood and cerebrospinal fluid. In MRI T2-mode, inflammatory changes were found in the white matter of the right hemisphere. The patient was treated with systemic acyclovir, itraconazole, metronidazole and ciprofloxacin for 3 weeks. Retinal detachment was observed in both eyes.

Conclusions: Acute retinal necrosis can be the single manifestation of herpes virus reactivation in patients after organ transplantation.

Show MeSH
Related in: MedlinePlus