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Measurement and comparison of skin dose using OneDose MOSFET and Mobile MOSFET for patients with acute lymphoblastic leukemia.

Mattar EH, Hammad LF, Al-Mohammed HI - Med. Sci. Monit. (2011)

Bottom Line: The results showed there was no variation between skin dose measured with OneDose MOSFET and Mobile MOSFET in all patients.Furthermore, the results showed for every anatomical site selected there was no significant difference in the dose delivered using either OneDose MOSFET detector or Mobile MOSFET as compared to the prescribed dose.The study concludes that One-Dose MOSFET detectors and Mobile MOSFET both give a direct read-out immediately after the treatment; therefore both detectors are suitable options when measuring skin dose for total body irradiation treatment.

View Article: PubMed Central - PubMed

Affiliation: Radiologic Sciences Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

ABSTRACT

Background: Total body irradiation is a protocol used to treat acute lymphoblastic leukemia in patients prior to bone marrow transplant. It is involved in the treatment of the whole body using a large radiation field with extended source-skin distance. Therefore measuring and monitoring the skin dose during the treatment is important. Two kinds of metal oxide semiconductor field effect transistor (OneDose MOSFET and mobile MOSEFT) dosimeter are used during the treatment delivery to measure the skin dose to specific points and compare it with the target prescribed dose. The objective of this study was to compare the variation of skin dose in patients with acute lymphatic leukemia (ALL) treated with total body irradiation (TBI) using OneDose MOSFET detectors and Mobile MOSFET, and then compare both results with the target prescribed dose.

Material/methods: The measurements involved 32 patient's (16 males, 16 females), aged between 14-30 years, with an average age of 22.41 years. One-Dose MOSFET and Mobile MOSFET dosimetry were performed at 10 different anatomical sites on every patient.

Results: The results showed there was no variation between skin dose measured with OneDose MOSFET and Mobile MOSFET in all patients. Furthermore, the results showed for every anatomical site selected there was no significant difference in the dose delivered using either OneDose MOSFET detector or Mobile MOSFET as compared to the prescribed dose.

Conclusions: The study concludes that One-Dose MOSFET detectors and Mobile MOSFET both give a direct read-out immediately after the treatment; therefore both detectors are suitable options when measuring skin dose for total body irradiation treatment.

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Related in: MedlinePlus

MOSEFT detectors reader.
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f1-medscimonit-17-7-mt51: MOSEFT detectors reader.

Mentions: OneDose MOSFET detectors verification system (Figure 1) (Sicel Technologies, Inc., Morrisville, NC; distributed by Med Tec, Orange City, USA), which is a solid-state detector, now is used in radiotherapy treatment applications to measure the entrance and exit dose during the treatment [3]. The system is small (3 mm diameter, 25 mm length), factory calibrated, wireless, and easy to use. The accuracy of the detectors, as specified by the manufacturer, is ±1 cGy for a dose of less than 20 cGy and ±5% for a dose of 20 to 500 cGy (Sicel Technologies Inc). The detectors are factory calibrated with a Co-60 beam with full build-up conditions. They are normalized to a 6-MV photon beam [5], and each detector is valid for 1 use only [3].


Measurement and comparison of skin dose using OneDose MOSFET and Mobile MOSFET for patients with acute lymphoblastic leukemia.

Mattar EH, Hammad LF, Al-Mohammed HI - Med. Sci. Monit. (2011)

MOSEFT detectors reader.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539560&req=5

f1-medscimonit-17-7-mt51: MOSEFT detectors reader.
Mentions: OneDose MOSFET detectors verification system (Figure 1) (Sicel Technologies, Inc., Morrisville, NC; distributed by Med Tec, Orange City, USA), which is a solid-state detector, now is used in radiotherapy treatment applications to measure the entrance and exit dose during the treatment [3]. The system is small (3 mm diameter, 25 mm length), factory calibrated, wireless, and easy to use. The accuracy of the detectors, as specified by the manufacturer, is ±1 cGy for a dose of less than 20 cGy and ±5% for a dose of 20 to 500 cGy (Sicel Technologies Inc). The detectors are factory calibrated with a Co-60 beam with full build-up conditions. They are normalized to a 6-MV photon beam [5], and each detector is valid for 1 use only [3].

Bottom Line: The results showed there was no variation between skin dose measured with OneDose MOSFET and Mobile MOSFET in all patients.Furthermore, the results showed for every anatomical site selected there was no significant difference in the dose delivered using either OneDose MOSFET detector or Mobile MOSFET as compared to the prescribed dose.The study concludes that One-Dose MOSFET detectors and Mobile MOSFET both give a direct read-out immediately after the treatment; therefore both detectors are suitable options when measuring skin dose for total body irradiation treatment.

View Article: PubMed Central - PubMed

Affiliation: Radiologic Sciences Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

ABSTRACT

Background: Total body irradiation is a protocol used to treat acute lymphoblastic leukemia in patients prior to bone marrow transplant. It is involved in the treatment of the whole body using a large radiation field with extended source-skin distance. Therefore measuring and monitoring the skin dose during the treatment is important. Two kinds of metal oxide semiconductor field effect transistor (OneDose MOSFET and mobile MOSEFT) dosimeter are used during the treatment delivery to measure the skin dose to specific points and compare it with the target prescribed dose. The objective of this study was to compare the variation of skin dose in patients with acute lymphatic leukemia (ALL) treated with total body irradiation (TBI) using OneDose MOSFET detectors and Mobile MOSFET, and then compare both results with the target prescribed dose.

Material/methods: The measurements involved 32 patient's (16 males, 16 females), aged between 14-30 years, with an average age of 22.41 years. One-Dose MOSFET and Mobile MOSFET dosimetry were performed at 10 different anatomical sites on every patient.

Results: The results showed there was no variation between skin dose measured with OneDose MOSFET and Mobile MOSFET in all patients. Furthermore, the results showed for every anatomical site selected there was no significant difference in the dose delivered using either OneDose MOSFET detector or Mobile MOSFET as compared to the prescribed dose.

Conclusions: The study concludes that One-Dose MOSFET detectors and Mobile MOSFET both give a direct read-out immediately after the treatment; therefore both detectors are suitable options when measuring skin dose for total body irradiation treatment.

Show MeSH
Related in: MedlinePlus