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Takotsubo cardiomyopathy--a clinical review.

Castillo Rivera AM, Ruiz-Bailén M, Rucabado Aguilar L - Med. Sci. Monit. (2011)

Bottom Line: The electrocardiographic, echocardiographic, and ventriculographic changes resolve spontaneously over a variable period of time (from days to months).There are a number of pathophysiological theories, none of which has been shown to be definitive, suggesting that all of them may be involved to some extent.The prognosis is generally favourable, and recurrence is very rare.

View Article: PubMed Central - PubMed

Affiliation: Department of Critical Care and Emergency, Intensive Medicine Unit, Jaén Hospital Complex, Jaén, Spain. ana.castillorivera@gmail.com

ABSTRACT
Stress cardiomyopathy is characterised by reversible left ventricular dysfunction. It simulates an acute coronary syndrome (ACS), presenting with precordial pain or dyspnoea, changes of the ST segment, T wave, or QTc interval on electrocardiogram, and raised cardiac enzymes. Typical findings are disturbances of segmental contractility (apical hypokinesia or akinesia), with normal epicardial coronary arteries. The true prevalence is unknown, as the syndrome may be under-diagnosed; it is more common in postmenopausal women. There is usually a trigger in the form of physical or psychological stress. The electrocardiographic, echocardiographic, and ventriculographic changes resolve spontaneously over a variable period of time (from days to months). There are a number of pathophysiological theories, none of which has been shown to be definitive, suggesting that all of them may be involved to some extent. The prognosis is generally favourable, and recurrence is very rare.

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Related in: MedlinePlus

Echocardiographic image in apical ballooning which is also observed mitral prolapse (P2).
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f1-medscimonit-17-6-ra135: Echocardiographic image in apical ballooning which is also observed mitral prolapse (P2).

Mentions: The typical finding is of apical ballooning of the left ventricle. This is due to akinesia, hypokinesia, or dyskinesia of the apical and middle segments of the LV and hyperkinesia of the basal segments [8,24,28] (Figure 1). Some disturbances of contractility are similar to those that occur in systemic hypertension due to an increase in afterload [113]. The LVEF is low or very low from the initial phase, with values below 30% in some cases [16,23,26,32,105] and up to 75% [64]. In the subacute phase, global and segmental systolic function and the electrocardiographic changes improve over a period of days, weeks, or a few months, until they stabilise with an LVEF above 50% [5,11,15,16,21–24, 56–69,114–119]. In general, echocardiography is normal at 1 year [7,14,21–24]; the rate of recovery is more rapid in Asians than in whites [120].


Takotsubo cardiomyopathy--a clinical review.

Castillo Rivera AM, Ruiz-Bailén M, Rucabado Aguilar L - Med. Sci. Monit. (2011)

Echocardiographic image in apical ballooning which is also observed mitral prolapse (P2).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539553&req=5

f1-medscimonit-17-6-ra135: Echocardiographic image in apical ballooning which is also observed mitral prolapse (P2).
Mentions: The typical finding is of apical ballooning of the left ventricle. This is due to akinesia, hypokinesia, or dyskinesia of the apical and middle segments of the LV and hyperkinesia of the basal segments [8,24,28] (Figure 1). Some disturbances of contractility are similar to those that occur in systemic hypertension due to an increase in afterload [113]. The LVEF is low or very low from the initial phase, with values below 30% in some cases [16,23,26,32,105] and up to 75% [64]. In the subacute phase, global and segmental systolic function and the electrocardiographic changes improve over a period of days, weeks, or a few months, until they stabilise with an LVEF above 50% [5,11,15,16,21–24, 56–69,114–119]. In general, echocardiography is normal at 1 year [7,14,21–24]; the rate of recovery is more rapid in Asians than in whites [120].

Bottom Line: The electrocardiographic, echocardiographic, and ventriculographic changes resolve spontaneously over a variable period of time (from days to months).There are a number of pathophysiological theories, none of which has been shown to be definitive, suggesting that all of them may be involved to some extent.The prognosis is generally favourable, and recurrence is very rare.

View Article: PubMed Central - PubMed

Affiliation: Department of Critical Care and Emergency, Intensive Medicine Unit, Jaén Hospital Complex, Jaén, Spain. ana.castillorivera@gmail.com

ABSTRACT
Stress cardiomyopathy is characterised by reversible left ventricular dysfunction. It simulates an acute coronary syndrome (ACS), presenting with precordial pain or dyspnoea, changes of the ST segment, T wave, or QTc interval on electrocardiogram, and raised cardiac enzymes. Typical findings are disturbances of segmental contractility (apical hypokinesia or akinesia), with normal epicardial coronary arteries. The true prevalence is unknown, as the syndrome may be under-diagnosed; it is more common in postmenopausal women. There is usually a trigger in the form of physical or psychological stress. The electrocardiographic, echocardiographic, and ventriculographic changes resolve spontaneously over a variable period of time (from days to months). There are a number of pathophysiological theories, none of which has been shown to be definitive, suggesting that all of them may be involved to some extent. The prognosis is generally favourable, and recurrence is very rare.

Show MeSH
Related in: MedlinePlus