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Underlying diseases in syncope of children in China.

Chen L, Wang C, Wang H, Tian H, Tang C, Jin H, Du J - Med. Sci. Monit. (2011)

Bottom Line: In 888 children with syncope, 175 (19.7%) had vasovagal syncope (VVS) with vasoinhibitory response, 35 (3.9%) had VVS with cardioinhibitory response, 73 (8.2%) had VVS with mixed response, 286 (32.2%) had postural orthostatic tachycardia syndrome (POTS), 19 (2.1%) had orthostatic hypotension, 7 (0.9%) had situational syncope, 13 (1.5%) had cardiogenic syncope, and 280 (31.5%) had unexplained syncope.The data suggest that neurally-mediated syncope was the most common cause in children with syncope.POTS and VVS were the most common hemodynamic patterns of neurally-mediated syncope.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Peking University 1st Hospital, Beijing, China.

ABSTRACT

Background: Syncope accounts for about 1-2% of emergency department visits, but the etiology in many patients with syncope is unclear. Recently, with the use of the head-up tilt test (HUT), the number of patients with unexplained syncope (UPS) has been decreasing; however, the spectrum of underlying diseases of syncope in children is unclear. This retrospective study aimed to analyze the spectrum of underlying diseases in children with syncope.

Material/methods: This multi-center clinical study consisted of 888 children (417 males, 471 females, aged 5-18 yrs, median age 12.0±3.0 yrs) with syncope who came from Beijing city, Hunan province, Hubei province and Shanghai from August 1999 to March 2009. The clinical and laboratory data of children were studied and the spectrum of underlying diseases in children with syncope was analyzed.

Results: In 888 children with syncope, 175 (19.7%) had vasovagal syncope (VVS) with vasoinhibitory response, 35 (3.9%) had VVS with cardioinhibitory response, 73 (8.2%) had VVS with mixed response, 286 (32.2%) had postural orthostatic tachycardia syndrome (POTS), 19 (2.1%) had orthostatic hypotension, 7 (0.9%) had situational syncope, 13 (1.5%) had cardiogenic syncope, and 280 (31.5%) had unexplained syncope.

Conclusions: The data suggest that neurally-mediated syncope was the most common cause in children with syncope. POTS and VVS were the most common hemodynamic patterns of neurally-mediated syncope.

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Related in: MedlinePlus

In this figure, we could see that the most common cause of syncope in children was postural orthostatic tachycardia syndrome (POTS) (32.2%). Unexplained syncope, vasovagal syncope-vasoinhibitory pattern (VVS-V), vasovagal syncope-mixed pattern (VVS-M), vasovagal syncope-cardioinhibitory pattern (VVS-C), orthostatic hypotension (OH), cardiogenic syncope and situational syncope accounted for 31.5%, 19.7%, 8.2%, 3.9%, 2.1%, 1.5% and 0.9%, respectively.
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f1-medscimonit-17-6-ph49: In this figure, we could see that the most common cause of syncope in children was postural orthostatic tachycardia syndrome (POTS) (32.2%). Unexplained syncope, vasovagal syncope-vasoinhibitory pattern (VVS-V), vasovagal syncope-mixed pattern (VVS-M), vasovagal syncope-cardioinhibitory pattern (VVS-C), orthostatic hypotension (OH), cardiogenic syncope and situational syncope accounted for 31.5%, 19.7%, 8.2%, 3.9%, 2.1%, 1.5% and 0.9%, respectively.

Mentions: VVS-vasoinhibitory pattern accounted for 175 cases (19.7%), whose ages ranged from 5 to 18 years (mean 13.0±3.0 years); 77 (44.0%) were male and 98 (56.0%) were female. There were 35 (3.9%) cases with VVS-cardioinhibitory pattern, with an age range from 6 to 18 years (mean 12.3±2.7 years old), of whom 17 (48.6%) were males and 18 (51.4%) were females; 73 (8.2%) cases had VVS-mixed pattern, including 26 (35.6%) males and 47 (64.4%) females, age range from 5 to 17 years, with a mean of 12.7±2.6 years (Table 1, Figure 1).


Underlying diseases in syncope of children in China.

Chen L, Wang C, Wang H, Tian H, Tang C, Jin H, Du J - Med. Sci. Monit. (2011)

In this figure, we could see that the most common cause of syncope in children was postural orthostatic tachycardia syndrome (POTS) (32.2%). Unexplained syncope, vasovagal syncope-vasoinhibitory pattern (VVS-V), vasovagal syncope-mixed pattern (VVS-M), vasovagal syncope-cardioinhibitory pattern (VVS-C), orthostatic hypotension (OH), cardiogenic syncope and situational syncope accounted for 31.5%, 19.7%, 8.2%, 3.9%, 2.1%, 1.5% and 0.9%, respectively.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539540&req=5

f1-medscimonit-17-6-ph49: In this figure, we could see that the most common cause of syncope in children was postural orthostatic tachycardia syndrome (POTS) (32.2%). Unexplained syncope, vasovagal syncope-vasoinhibitory pattern (VVS-V), vasovagal syncope-mixed pattern (VVS-M), vasovagal syncope-cardioinhibitory pattern (VVS-C), orthostatic hypotension (OH), cardiogenic syncope and situational syncope accounted for 31.5%, 19.7%, 8.2%, 3.9%, 2.1%, 1.5% and 0.9%, respectively.
Mentions: VVS-vasoinhibitory pattern accounted for 175 cases (19.7%), whose ages ranged from 5 to 18 years (mean 13.0±3.0 years); 77 (44.0%) were male and 98 (56.0%) were female. There were 35 (3.9%) cases with VVS-cardioinhibitory pattern, with an age range from 6 to 18 years (mean 12.3±2.7 years old), of whom 17 (48.6%) were males and 18 (51.4%) were females; 73 (8.2%) cases had VVS-mixed pattern, including 26 (35.6%) males and 47 (64.4%) females, age range from 5 to 17 years, with a mean of 12.7±2.6 years (Table 1, Figure 1).

Bottom Line: In 888 children with syncope, 175 (19.7%) had vasovagal syncope (VVS) with vasoinhibitory response, 35 (3.9%) had VVS with cardioinhibitory response, 73 (8.2%) had VVS with mixed response, 286 (32.2%) had postural orthostatic tachycardia syndrome (POTS), 19 (2.1%) had orthostatic hypotension, 7 (0.9%) had situational syncope, 13 (1.5%) had cardiogenic syncope, and 280 (31.5%) had unexplained syncope.The data suggest that neurally-mediated syncope was the most common cause in children with syncope.POTS and VVS were the most common hemodynamic patterns of neurally-mediated syncope.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Peking University 1st Hospital, Beijing, China.

ABSTRACT

Background: Syncope accounts for about 1-2% of emergency department visits, but the etiology in many patients with syncope is unclear. Recently, with the use of the head-up tilt test (HUT), the number of patients with unexplained syncope (UPS) has been decreasing; however, the spectrum of underlying diseases of syncope in children is unclear. This retrospective study aimed to analyze the spectrum of underlying diseases in children with syncope.

Material/methods: This multi-center clinical study consisted of 888 children (417 males, 471 females, aged 5-18 yrs, median age 12.0±3.0 yrs) with syncope who came from Beijing city, Hunan province, Hubei province and Shanghai from August 1999 to March 2009. The clinical and laboratory data of children were studied and the spectrum of underlying diseases in children with syncope was analyzed.

Results: In 888 children with syncope, 175 (19.7%) had vasovagal syncope (VVS) with vasoinhibitory response, 35 (3.9%) had VVS with cardioinhibitory response, 73 (8.2%) had VVS with mixed response, 286 (32.2%) had postural orthostatic tachycardia syndrome (POTS), 19 (2.1%) had orthostatic hypotension, 7 (0.9%) had situational syncope, 13 (1.5%) had cardiogenic syncope, and 280 (31.5%) had unexplained syncope.

Conclusions: The data suggest that neurally-mediated syncope was the most common cause in children with syncope. POTS and VVS were the most common hemodynamic patterns of neurally-mediated syncope.

Show MeSH
Related in: MedlinePlus