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Post-processing analysis of transient-evoked otoacoustic emissions to detect 4 kHz-notch hearing impairment--a pilot study.

Zimatore G, Fetoni AR, Paludetti G, Cavagnaro M, Podda MV, Troiani D - Med. Sci. Monit. (2011)

Bottom Line: Audiometric examinations indicated 14 ears as impaired-hearing (IH), while the TEOAE ILO92 whole reproducibility parameter (WWR) indicated as IH 7 signals out of 14 (50%).The proposed new parameter indicated as IH 9 signals out of 14 (64%), reducing the number of false negative cases of WWR.In this preliminary study there is evidence that the new parameter RAD2D defines the topology and the quantification of the damage in the inner ear.

View Article: PubMed Central - PubMed

Affiliation: Institute of Otolaryngology, Catholic University School of Medicine, Rome, Italy.

ABSTRACT

Background: To identify a parameter to distinguish normal hearing from hearing impairment in the early stages. The parameter was obtained from transient-evoked otoacoustic emissions (TEOAEs), overcoming the limitations of the usually adopted waveform descriptive parameters which may fail in standard clinical screenings.

Material/methods: Audiometric examinations and TEOAE analysis were conducted on 15 normal ears and on 14 hearing-impaired ears that exhibited an audiometric notch around 4 kHz. TEOAE signals were analyzed through a multivariate technique to filter out the individual variability and to highlight the dynamic structure of the signals. The new parameter (named radius 2-dimension--RAD2D) was defined and evaluated for simulated TEOAE signals modeling a different amount of hearing impairment.

Results: Audiometric examinations indicated 14 ears as impaired-hearing (IH), while the TEOAE ILO92 whole reproducibility parameter (WWR) indicated as IH 7 signals out of 14 (50%). The proposed new parameter indicated as IH 9 signals out of 14 (64%), reducing the number of false negative cases of WWR.

Conclusions: In this preliminary study there is evidence that the new parameter RAD2D defines the topology and the quantification of the damage in the inner ear. The proposed protocol can be useful in hearing screenings to identify hearing impairments much earlier than conventional pure tone audiometry and TEOAE pass/fail test.

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Related in: MedlinePlus

The reference parameter RAD2D (crosses) as a function of the number of amplifiers switched off in the simulated signals. The linear fitting is plotted (thin line, slope 0.199, intercept at 0.204). The dashed line corresponds to the value of RAD2D (0.21) reckoned from mean RQA parameters of TEOAE from the 15 normal ears; the black bold line corresponds to the value of RAD2D (1.78) reckoned from mean RQA parameters of TEOAE from the 14 IH ears (see text for details).
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f4-medscimonit-17-6-mt41: The reference parameter RAD2D (crosses) as a function of the number of amplifiers switched off in the simulated signals. The linear fitting is plotted (thin line, slope 0.199, intercept at 0.204). The dashed line corresponds to the value of RAD2D (0.21) reckoned from mean RQA parameters of TEOAE from the 15 normal ears; the black bold line corresponds to the value of RAD2D (1.78) reckoned from mean RQA parameters of TEOAE from the 14 IH ears (see text for details).

Mentions: RAD2D was evaluated by combining RQA and PCA techniques for simulated and measured TEOAEs. Figure 4 shows the RAD2D values calculated for simulated signals with an increasing number of silenced partitions (crosses). The dashed line in Figure 4 corresponds to the value of RAD2D (0.21) obtained by considering the mean values of the RQA parameters obtained from the 15 normal hearing ears, whereas the black bold line corresponds to the value of RAD2D (1.78) obtained from the mean values of the RQA parameters of the 14 IH ears.


Post-processing analysis of transient-evoked otoacoustic emissions to detect 4 kHz-notch hearing impairment--a pilot study.

Zimatore G, Fetoni AR, Paludetti G, Cavagnaro M, Podda MV, Troiani D - Med. Sci. Monit. (2011)

The reference parameter RAD2D (crosses) as a function of the number of amplifiers switched off in the simulated signals. The linear fitting is plotted (thin line, slope 0.199, intercept at 0.204). The dashed line corresponds to the value of RAD2D (0.21) reckoned from mean RQA parameters of TEOAE from the 15 normal ears; the black bold line corresponds to the value of RAD2D (1.78) reckoned from mean RQA parameters of TEOAE from the 14 IH ears (see text for details).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539534&req=5

f4-medscimonit-17-6-mt41: The reference parameter RAD2D (crosses) as a function of the number of amplifiers switched off in the simulated signals. The linear fitting is plotted (thin line, slope 0.199, intercept at 0.204). The dashed line corresponds to the value of RAD2D (0.21) reckoned from mean RQA parameters of TEOAE from the 15 normal ears; the black bold line corresponds to the value of RAD2D (1.78) reckoned from mean RQA parameters of TEOAE from the 14 IH ears (see text for details).
Mentions: RAD2D was evaluated by combining RQA and PCA techniques for simulated and measured TEOAEs. Figure 4 shows the RAD2D values calculated for simulated signals with an increasing number of silenced partitions (crosses). The dashed line in Figure 4 corresponds to the value of RAD2D (0.21) obtained by considering the mean values of the RQA parameters obtained from the 15 normal hearing ears, whereas the black bold line corresponds to the value of RAD2D (1.78) obtained from the mean values of the RQA parameters of the 14 IH ears.

Bottom Line: Audiometric examinations indicated 14 ears as impaired-hearing (IH), while the TEOAE ILO92 whole reproducibility parameter (WWR) indicated as IH 7 signals out of 14 (50%).The proposed new parameter indicated as IH 9 signals out of 14 (64%), reducing the number of false negative cases of WWR.In this preliminary study there is evidence that the new parameter RAD2D defines the topology and the quantification of the damage in the inner ear.

View Article: PubMed Central - PubMed

Affiliation: Institute of Otolaryngology, Catholic University School of Medicine, Rome, Italy.

ABSTRACT

Background: To identify a parameter to distinguish normal hearing from hearing impairment in the early stages. The parameter was obtained from transient-evoked otoacoustic emissions (TEOAEs), overcoming the limitations of the usually adopted waveform descriptive parameters which may fail in standard clinical screenings.

Material/methods: Audiometric examinations and TEOAE analysis were conducted on 15 normal ears and on 14 hearing-impaired ears that exhibited an audiometric notch around 4 kHz. TEOAE signals were analyzed through a multivariate technique to filter out the individual variability and to highlight the dynamic structure of the signals. The new parameter (named radius 2-dimension--RAD2D) was defined and evaluated for simulated TEOAE signals modeling a different amount of hearing impairment.

Results: Audiometric examinations indicated 14 ears as impaired-hearing (IH), while the TEOAE ILO92 whole reproducibility parameter (WWR) indicated as IH 7 signals out of 14 (50%). The proposed new parameter indicated as IH 9 signals out of 14 (64%), reducing the number of false negative cases of WWR.

Conclusions: In this preliminary study there is evidence that the new parameter RAD2D defines the topology and the quantification of the damage in the inner ear. The proposed protocol can be useful in hearing screenings to identify hearing impairments much earlier than conventional pure tone audiometry and TEOAE pass/fail test.

Show MeSH
Related in: MedlinePlus