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Post-processing analysis of transient-evoked otoacoustic emissions to detect 4 kHz-notch hearing impairment--a pilot study.

Zimatore G, Fetoni AR, Paludetti G, Cavagnaro M, Podda MV, Troiani D - Med. Sci. Monit. (2011)

Bottom Line: Audiometric examinations indicated 14 ears as impaired-hearing (IH), while the TEOAE ILO92 whole reproducibility parameter (WWR) indicated as IH 7 signals out of 14 (50%).The proposed new parameter indicated as IH 9 signals out of 14 (64%), reducing the number of false negative cases of WWR.In this preliminary study there is evidence that the new parameter RAD2D defines the topology and the quantification of the damage in the inner ear.

View Article: PubMed Central - PubMed

Affiliation: Institute of Otolaryngology, Catholic University School of Medicine, Rome, Italy.

ABSTRACT

Background: To identify a parameter to distinguish normal hearing from hearing impairment in the early stages. The parameter was obtained from transient-evoked otoacoustic emissions (TEOAEs), overcoming the limitations of the usually adopted waveform descriptive parameters which may fail in standard clinical screenings.

Material/methods: Audiometric examinations and TEOAE analysis were conducted on 15 normal ears and on 14 hearing-impaired ears that exhibited an audiometric notch around 4 kHz. TEOAE signals were analyzed through a multivariate technique to filter out the individual variability and to highlight the dynamic structure of the signals. The new parameter (named radius 2-dimension--RAD2D) was defined and evaluated for simulated TEOAE signals modeling a different amount of hearing impairment.

Results: Audiometric examinations indicated 14 ears as impaired-hearing (IH), while the TEOAE ILO92 whole reproducibility parameter (WWR) indicated as IH 7 signals out of 14 (50%). The proposed new parameter indicated as IH 9 signals out of 14 (64%), reducing the number of false negative cases of WWR.

Conclusions: In this preliminary study there is evidence that the new parameter RAD2D defines the topology and the quantification of the damage in the inner ear. The proposed protocol can be useful in hearing screenings to identify hearing impairments much earlier than conventional pure tone audiometry and TEOAE pass/fail test.

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Related in: MedlinePlus

Mean pure-tone hearing thresholds (PTT) averaged across ears of the Normal (bold line) and IH (thin line) groups. Bars represent the standard deviation from the mean. IH ears included in this study showed a 4 kHz notch greater than 30 dB HL using pure-tone audiometry; at this frequency the mean threshold level was 59.6±17.4 dB HL.
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f1-medscimonit-17-6-mt41: Mean pure-tone hearing thresholds (PTT) averaged across ears of the Normal (bold line) and IH (thin line) groups. Bars represent the standard deviation from the mean. IH ears included in this study showed a 4 kHz notch greater than 30 dB HL using pure-tone audiometry; at this frequency the mean threshold level was 59.6±17.4 dB HL.

Mentions: The subjects’ age distributions of the 2 groups was not statistically different (t-test p=0.095). The recorded TEOAEs in all ears of the Normal group and in 50% ears (7/14) of the IH group had the WWR ≥70%. In Figure 1, the audiogram levels (mean values and standard deviations) are shown for the normal hearing ears (bold line) and for the IH ears (thin line). At 0.5, 1, 2 kHz no differences were found – on the contrary, the audiometric thresholds belonging to IH ears were characterized by a deep and narrow notch close to 4 kHz, that in all patients was higher than 30 dB HL with a mean value of 59.6±17.4 dB HL, as compared to the flat shape of the normal hearing audiograms. The standard deviations demonstrated a large variability in IH subjects at 4 kHz and 8 kHz.


Post-processing analysis of transient-evoked otoacoustic emissions to detect 4 kHz-notch hearing impairment--a pilot study.

Zimatore G, Fetoni AR, Paludetti G, Cavagnaro M, Podda MV, Troiani D - Med. Sci. Monit. (2011)

Mean pure-tone hearing thresholds (PTT) averaged across ears of the Normal (bold line) and IH (thin line) groups. Bars represent the standard deviation from the mean. IH ears included in this study showed a 4 kHz notch greater than 30 dB HL using pure-tone audiometry; at this frequency the mean threshold level was 59.6±17.4 dB HL.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539534&req=5

f1-medscimonit-17-6-mt41: Mean pure-tone hearing thresholds (PTT) averaged across ears of the Normal (bold line) and IH (thin line) groups. Bars represent the standard deviation from the mean. IH ears included in this study showed a 4 kHz notch greater than 30 dB HL using pure-tone audiometry; at this frequency the mean threshold level was 59.6±17.4 dB HL.
Mentions: The subjects’ age distributions of the 2 groups was not statistically different (t-test p=0.095). The recorded TEOAEs in all ears of the Normal group and in 50% ears (7/14) of the IH group had the WWR ≥70%. In Figure 1, the audiogram levels (mean values and standard deviations) are shown for the normal hearing ears (bold line) and for the IH ears (thin line). At 0.5, 1, 2 kHz no differences were found – on the contrary, the audiometric thresholds belonging to IH ears were characterized by a deep and narrow notch close to 4 kHz, that in all patients was higher than 30 dB HL with a mean value of 59.6±17.4 dB HL, as compared to the flat shape of the normal hearing audiograms. The standard deviations demonstrated a large variability in IH subjects at 4 kHz and 8 kHz.

Bottom Line: Audiometric examinations indicated 14 ears as impaired-hearing (IH), while the TEOAE ILO92 whole reproducibility parameter (WWR) indicated as IH 7 signals out of 14 (50%).The proposed new parameter indicated as IH 9 signals out of 14 (64%), reducing the number of false negative cases of WWR.In this preliminary study there is evidence that the new parameter RAD2D defines the topology and the quantification of the damage in the inner ear.

View Article: PubMed Central - PubMed

Affiliation: Institute of Otolaryngology, Catholic University School of Medicine, Rome, Italy.

ABSTRACT

Background: To identify a parameter to distinguish normal hearing from hearing impairment in the early stages. The parameter was obtained from transient-evoked otoacoustic emissions (TEOAEs), overcoming the limitations of the usually adopted waveform descriptive parameters which may fail in standard clinical screenings.

Material/methods: Audiometric examinations and TEOAE analysis were conducted on 15 normal ears and on 14 hearing-impaired ears that exhibited an audiometric notch around 4 kHz. TEOAE signals were analyzed through a multivariate technique to filter out the individual variability and to highlight the dynamic structure of the signals. The new parameter (named radius 2-dimension--RAD2D) was defined and evaluated for simulated TEOAE signals modeling a different amount of hearing impairment.

Results: Audiometric examinations indicated 14 ears as impaired-hearing (IH), while the TEOAE ILO92 whole reproducibility parameter (WWR) indicated as IH 7 signals out of 14 (50%). The proposed new parameter indicated as IH 9 signals out of 14 (64%), reducing the number of false negative cases of WWR.

Conclusions: In this preliminary study there is evidence that the new parameter RAD2D defines the topology and the quantification of the damage in the inner ear. The proposed protocol can be useful in hearing screenings to identify hearing impairments much earlier than conventional pure tone audiometry and TEOAE pass/fail test.

Show MeSH
Related in: MedlinePlus