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Circadian variation of acute st segment elevation myocardial infarction by anatomic location in a Turkish cohort.

Celik M, Celik T, Iyısoy A, Yuksel UC, Bugan B, Demırkol S, Kabul K, Gokoglan Y, Kılıc S - Med. Sci. Monit. (2011)

Bottom Line: Characteristics of patients by site of infarction (anterior vs. inferior) were compared.The frequency of onset of acute inferior MI as determined by onset of pain exhibited significant circadian variation among the 4 time periods, demonstrating bimodal peaks (midnight to 06:00 AM and 06:00 AM to noon) and a trough between noon to midnight.This may be related to genetic and⁄or demographic characteristics of the Turkish population.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Gulhane Military Medical Academy, School of Medicine, Etlik-Ankara, Turkey. benturgay@yahoo.com

ABSTRACT

Background: To evaluate the relationship between site of infarction (anterior vs. inferior) and circadian variation in patients with ST segment elevation myocardial infarction (STEMI) in a Turkish cohort.

Material/methods: This restrospective study enrolled 465 patients (407 male, mean age 65±7 years) with STEMI. Patients were then categorised into 4 6-hour increments according to the time of day during which the symptoms began (12:00 AM-06:00 AM, 06:00 AM-12:00 PM; 12:00 PM-06:00 PM and 06:00 PM-12:00 AM hours). Characteristics of patients by site of infarction (anterior vs. inferior) were compared.

Results: The frequency of onset of acute anterior MI as determined by onset of pain demonstrated significant circadian variation among the 4 time periods, demonstrating bimodal peaks (afternoon and morning) and a trough between 06:00 PM to 06:00 AM. The incidence of occurrence of MI between 06:00 AM to 06:00 PM was 4.50 times that of the average frequency of the remaining 12 hours of the day. The frequency of onset of acute inferior MI as determined by onset of pain exhibited significant circadian variation among the 4 time periods, demonstrating bimodal peaks (midnight to 06:00 AM and 06:00 AM to noon) and a trough between noon to midnight. The incidence of occurrence of MI between midnight to noon was 4.25 times that of the average frequency of the remaining 12 hours of the day.

Conclusions: Different circadian periodicity in the time of onset of STEMI was found regarding infarction site in a Turkish cohort. This may be related to genetic and⁄or demographic characteristics of the Turkish population.

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Related in: MedlinePlus

Circadian distribution of inferior myocardial infarction. Compared with other times of the day, anterior infarctions were more common from midnight to noon.
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f2-medscimonit-17-4-cr210: Circadian distribution of inferior myocardial infarction. Compared with other times of the day, anterior infarctions were more common from midnight to noon.

Mentions: The frequency of onset of acute inferior MI as determined by onset of pain exhibited significant circadian variation among the 4 time periods, demonstrating bimodal peaks (midnight to 06:00 AM and 06:00 AM to noon) and a trough between noon to midnight (Table 4; Figure 2). The onset of MI was between 12:00 AM and 06:00 AM hours in 85 patients (38.3%); 06:00 AM and 12:00 PM hours in 103 patients (46.5%); between 12:00 PM and 06:00 PM hours in 24 patients (10.7%) and between 06:00 PM and 12:00 AM hours in 11 patients (4.5%). The incidences of MI between 12:00 AM and 12:00 PM hours were significantly higher when compared with the 2 other 6-h periods (p<0.001). The incidence of occurrence of MI between midnight to noon was 4.25 times that of the average frequency of the remaining 12 hours of the day.


Circadian variation of acute st segment elevation myocardial infarction by anatomic location in a Turkish cohort.

Celik M, Celik T, Iyısoy A, Yuksel UC, Bugan B, Demırkol S, Kabul K, Gokoglan Y, Kılıc S - Med. Sci. Monit. (2011)

Circadian distribution of inferior myocardial infarction. Compared with other times of the day, anterior infarctions were more common from midnight to noon.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539529&req=5

f2-medscimonit-17-4-cr210: Circadian distribution of inferior myocardial infarction. Compared with other times of the day, anterior infarctions were more common from midnight to noon.
Mentions: The frequency of onset of acute inferior MI as determined by onset of pain exhibited significant circadian variation among the 4 time periods, demonstrating bimodal peaks (midnight to 06:00 AM and 06:00 AM to noon) and a trough between noon to midnight (Table 4; Figure 2). The onset of MI was between 12:00 AM and 06:00 AM hours in 85 patients (38.3%); 06:00 AM and 12:00 PM hours in 103 patients (46.5%); between 12:00 PM and 06:00 PM hours in 24 patients (10.7%) and between 06:00 PM and 12:00 AM hours in 11 patients (4.5%). The incidences of MI between 12:00 AM and 12:00 PM hours were significantly higher when compared with the 2 other 6-h periods (p<0.001). The incidence of occurrence of MI between midnight to noon was 4.25 times that of the average frequency of the remaining 12 hours of the day.

Bottom Line: Characteristics of patients by site of infarction (anterior vs. inferior) were compared.The frequency of onset of acute inferior MI as determined by onset of pain exhibited significant circadian variation among the 4 time periods, demonstrating bimodal peaks (midnight to 06:00 AM and 06:00 AM to noon) and a trough between noon to midnight.This may be related to genetic and⁄or demographic characteristics of the Turkish population.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Gulhane Military Medical Academy, School of Medicine, Etlik-Ankara, Turkey. benturgay@yahoo.com

ABSTRACT

Background: To evaluate the relationship between site of infarction (anterior vs. inferior) and circadian variation in patients with ST segment elevation myocardial infarction (STEMI) in a Turkish cohort.

Material/methods: This restrospective study enrolled 465 patients (407 male, mean age 65±7 years) with STEMI. Patients were then categorised into 4 6-hour increments according to the time of day during which the symptoms began (12:00 AM-06:00 AM, 06:00 AM-12:00 PM; 12:00 PM-06:00 PM and 06:00 PM-12:00 AM hours). Characteristics of patients by site of infarction (anterior vs. inferior) were compared.

Results: The frequency of onset of acute anterior MI as determined by onset of pain demonstrated significant circadian variation among the 4 time periods, demonstrating bimodal peaks (afternoon and morning) and a trough between 06:00 PM to 06:00 AM. The incidence of occurrence of MI between 06:00 AM to 06:00 PM was 4.50 times that of the average frequency of the remaining 12 hours of the day. The frequency of onset of acute inferior MI as determined by onset of pain exhibited significant circadian variation among the 4 time periods, demonstrating bimodal peaks (midnight to 06:00 AM and 06:00 AM to noon) and a trough between noon to midnight. The incidence of occurrence of MI between midnight to noon was 4.25 times that of the average frequency of the remaining 12 hours of the day.

Conclusions: Different circadian periodicity in the time of onset of STEMI was found regarding infarction site in a Turkish cohort. This may be related to genetic and⁄or demographic characteristics of the Turkish population.

Show MeSH
Related in: MedlinePlus