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A case report of spindle cell (sarcomatoid) carcinoma of the larynx.

Boamah H, Ballard B - Case Rep Med (2012)

Bottom Line: Most spindle cell tumors are polypoid and pedunculated; they are often detected at an early stage, removed by polypectomy during diagnosis, and tend to have a very good prognosis.We present a case of spindle cell carcinoma in a 67-year-old Caucasian male who presented with progressive hoarseness of his voice, dysphagia, odynophagia and a 20-pound weight loss.His symptoms gradually improved, and he regained good control of his voice.

View Article: PubMed Central - PubMed

Affiliation: Meharry Medical College, 1005 DR DB Todd Boulevard, Nashville, TN 37208, USA.

ABSTRACT
Spindle cell carcinoma (SpCC) or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma which comprises 2% to 3% of all laryngeal cancers. It is considered to be a biphasic tumor that is composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma with sarcomatous appearance. Most spindle cell tumors are polypoid and pedunculated; they are often detected at an early stage, removed by polypectomy during diagnosis, and tend to have a very good prognosis. We present a case of spindle cell carcinoma in a 67-year-old Caucasian male who presented with progressive hoarseness of his voice, dysphagia, odynophagia and a 20-pound weight loss. The patient underwent direct laryngoscopy with excision of the malignant mass and received radiation therapy. His symptoms gradually improved, and he regained good control of his voice.

No MeSH data available.


Related in: MedlinePlus

CT of the neck with contrast: There is 7 mm polypoid mass involving the anterior commissure of the vocal cords. The nasopharynx, and pharynx, peripharyngeal spaces appear unremarkable, as well as the parotid and submandibular salivary glands. There is no significant neck adenopathy noted.
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fig1: CT of the neck with contrast: There is 7 mm polypoid mass involving the anterior commissure of the vocal cords. The nasopharynx, and pharynx, peripharyngeal spaces appear unremarkable, as well as the parotid and submandibular salivary glands. There is no significant neck adenopathy noted.

Mentions: A CT scan of his neck with contrast revealed a 7 mm polypoid mass involving the anterior commissure of the vocal cords; however the nasopharynx, pharynx, peripharyngeal spaces and epiglottis appeared unremarkable. The parotid gland and submandibular salivary glands were normal; however the CT showed that the thyroid gland was enlarged. There was no adenopathy noted however (Figure 1).


A case report of spindle cell (sarcomatoid) carcinoma of the larynx.

Boamah H, Ballard B - Case Rep Med (2012)

CT of the neck with contrast: There is 7 mm polypoid mass involving the anterior commissure of the vocal cords. The nasopharynx, and pharynx, peripharyngeal spaces appear unremarkable, as well as the parotid and submandibular salivary glands. There is no significant neck adenopathy noted.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3539458&req=5

fig1: CT of the neck with contrast: There is 7 mm polypoid mass involving the anterior commissure of the vocal cords. The nasopharynx, and pharynx, peripharyngeal spaces appear unremarkable, as well as the parotid and submandibular salivary glands. There is no significant neck adenopathy noted.
Mentions: A CT scan of his neck with contrast revealed a 7 mm polypoid mass involving the anterior commissure of the vocal cords; however the nasopharynx, pharynx, peripharyngeal spaces and epiglottis appeared unremarkable. The parotid gland and submandibular salivary glands were normal; however the CT showed that the thyroid gland was enlarged. There was no adenopathy noted however (Figure 1).

Bottom Line: Most spindle cell tumors are polypoid and pedunculated; they are often detected at an early stage, removed by polypectomy during diagnosis, and tend to have a very good prognosis.We present a case of spindle cell carcinoma in a 67-year-old Caucasian male who presented with progressive hoarseness of his voice, dysphagia, odynophagia and a 20-pound weight loss.His symptoms gradually improved, and he regained good control of his voice.

View Article: PubMed Central - PubMed

Affiliation: Meharry Medical College, 1005 DR DB Todd Boulevard, Nashville, TN 37208, USA.

ABSTRACT
Spindle cell carcinoma (SpCC) or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma which comprises 2% to 3% of all laryngeal cancers. It is considered to be a biphasic tumor that is composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma with sarcomatous appearance. Most spindle cell tumors are polypoid and pedunculated; they are often detected at an early stage, removed by polypectomy during diagnosis, and tend to have a very good prognosis. We present a case of spindle cell carcinoma in a 67-year-old Caucasian male who presented with progressive hoarseness of his voice, dysphagia, odynophagia and a 20-pound weight loss. The patient underwent direct laryngoscopy with excision of the malignant mass and received radiation therapy. His symptoms gradually improved, and he regained good control of his voice.

No MeSH data available.


Related in: MedlinePlus