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Basal cell carcinoma: a single-center experience.

Abbas OL, Borman H - ISRN Dermatol (2012)

Bottom Line: Although there is relatively low attributable mortality, the morbidity and cost of treatment are significant.A large body of information serves as a foundation for oncologic principles, diagnosis methods, surgical excisions, follow-up protocols, and reconstructive methodologies that are currently in use.Surgical ablation remains the mainstay of treatment.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic, Reconstructive and Aesthetic Surgery, Baskent University Faculty of Medicine, 40000 Ankara, Turkey.

ABSTRACT
Background. Basal cell carcinoma comprises the vast majority of skin cancers. It predominantly affects fair-skinned individuals, and its incidence is rising rapidly. Etiology may be multifactorial, but sun exposure appears to play a critical role. When detected early, the prognosis is excellent. Thus appropriate diagnosis, treatment, and surveillance are of utmost importance. Methods. From January 1994 to May 2012, 518 basal cell carcinomas were excised in our clinic. Data were collected retrospectively. Results. During 18-year period, 518 BCCs were excised from 486 patients. Most of the patients were males with a median age of 65.6 years. Most of the basal cell carcinomas were located in the head region. Nodular histological subtype dominated our series. Six percent of the excised lesions required reexcision because of involved margins. Our recurrence rate was 6.94% with the nose and the periauricular and periocular regions being the most common sites of occurrence. Conclusion. Although there is relatively low attributable mortality, the morbidity and cost of treatment are significant. A large body of information serves as a foundation for oncologic principles, diagnosis methods, surgical excisions, follow-up protocols, and reconstructive methodologies that are currently in use. Surgical ablation remains the mainstay of treatment.

No MeSH data available.


Related in: MedlinePlus

Morpheaform BCC.
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Related In: Results  -  Collection


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fig8: Morpheaform BCC.

Mentions: Morphea-like BCC is an aggressive rare variant accounting for 3.7% of all our BCCs. It presents as firm plaques that is yellow or white with ill-defined border (Figure 8).Tumor cells induce a proliferation of fibroblasts within the dermis and an increased collagen deposition (sclerosis) that clinically resembles a scar. The extent of the tumor is usually not apparent on clinical examination. Morpheaform BCCs had the highest percentage of positive margins after excision. Thirty-three percent of our morpheaform BCCs had involved margins after excision. Mohs micrographic surgery is valuable in the management of these lesions.


Basal cell carcinoma: a single-center experience.

Abbas OL, Borman H - ISRN Dermatol (2012)

Morpheaform BCC.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539390&req=5

fig8: Morpheaform BCC.
Mentions: Morphea-like BCC is an aggressive rare variant accounting for 3.7% of all our BCCs. It presents as firm plaques that is yellow or white with ill-defined border (Figure 8).Tumor cells induce a proliferation of fibroblasts within the dermis and an increased collagen deposition (sclerosis) that clinically resembles a scar. The extent of the tumor is usually not apparent on clinical examination. Morpheaform BCCs had the highest percentage of positive margins after excision. Thirty-three percent of our morpheaform BCCs had involved margins after excision. Mohs micrographic surgery is valuable in the management of these lesions.

Bottom Line: Although there is relatively low attributable mortality, the morbidity and cost of treatment are significant.A large body of information serves as a foundation for oncologic principles, diagnosis methods, surgical excisions, follow-up protocols, and reconstructive methodologies that are currently in use.Surgical ablation remains the mainstay of treatment.

View Article: PubMed Central - PubMed

Affiliation: Department of Plastic, Reconstructive and Aesthetic Surgery, Baskent University Faculty of Medicine, 40000 Ankara, Turkey.

ABSTRACT
Background. Basal cell carcinoma comprises the vast majority of skin cancers. It predominantly affects fair-skinned individuals, and its incidence is rising rapidly. Etiology may be multifactorial, but sun exposure appears to play a critical role. When detected early, the prognosis is excellent. Thus appropriate diagnosis, treatment, and surveillance are of utmost importance. Methods. From January 1994 to May 2012, 518 basal cell carcinomas were excised in our clinic. Data were collected retrospectively. Results. During 18-year period, 518 BCCs were excised from 486 patients. Most of the patients were males with a median age of 65.6 years. Most of the basal cell carcinomas were located in the head region. Nodular histological subtype dominated our series. Six percent of the excised lesions required reexcision because of involved margins. Our recurrence rate was 6.94% with the nose and the periauricular and periocular regions being the most common sites of occurrence. Conclusion. Although there is relatively low attributable mortality, the morbidity and cost of treatment are significant. A large body of information serves as a foundation for oncologic principles, diagnosis methods, surgical excisions, follow-up protocols, and reconstructive methodologies that are currently in use. Surgical ablation remains the mainstay of treatment.

No MeSH data available.


Related in: MedlinePlus