Limits...
Intestinal/Peritoneal tuberculosis in children: an analysis of autopsy cases.

Ridaura-Sanz C, López-Corella E, Lopez-Ridaura R - Tuberc Res Treat (2012)

Bottom Line: Infection by Mycobacterium bovis is not infrequently identified in Mexico.Its relation to nonpasteurized milk products ingestion is well recognized with primary infection usually in the intestinal tract.The clinical differentiation of these conditions is difficult.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, National Institute of Pediatrics, 04530 Mexico City, DF, Mexico.

ABSTRACT
Infection by Mycobacterium bovis is not infrequently identified in Mexico. Its relation to nonpasteurized milk products ingestion is well recognized with primary infection usually in the intestinal tract. The term "abdominal tuberculosis" includes peritoneal as well as primary and secondary intestinal tuberculosis. The clinical differentiation of these conditions is difficult. In this work, we reviewed the clinical and pathological features of 24 cases of children dying with tuberculosis in whom autopsy revealed abdominal disease in a referral hospital in Mexico City. We identified 8 cases of primary intestinal tuberculosis, with documentation of M. bovis in 6 of them, and 9 cases of secondary intestinal tuberculosis (primary pulmonary disease), all negative to M. bovis. Seven patients had peritoneal tuberculosis without intestinal lesions and with active pulmonary disease in 4 of them, and of the remaining three, two had mesenteric lymph node involvement suggesting healed intestinal disease. In this approach to abdominal tuberculosis, postmortem analysis was able to differentiate primary from secondary intestinal tuberculosis and to define the nature of peritoneal involvement. This discrimination gives rise to different diagnostic approaches and epidemiological and preventive actions, particularly in countries where tuberculosis is endemic and infection by M. bovis continues to be identified.

No MeSH data available.


Related in: MedlinePlus

Peritoneal tuberculosis. Numerous granulomas on the abdominal aspect of the diaphragm.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3539372&req=5

fig2: Peritoneal tuberculosis. Numerous granulomas on the abdominal aspect of the diaphragm.

Mentions: Of the 153 cases of tuberculosis in our autopsy series, 24 (15.6%) patients had intestinal or peritoneal tuberculous disease. All of them had clinical manifestations consistent with the disease. Intestinal disease was present in 17 (71%), 14 of them with peritoneal involvement. Seven cases (29%) had peritoneal tuberculosis without presence of intestinal disease (isolated peritoneal disease). Most cases occurred before the year 2000, and none of our cases was associated with AIDS [17].


Intestinal/Peritoneal tuberculosis in children: an analysis of autopsy cases.

Ridaura-Sanz C, López-Corella E, Lopez-Ridaura R - Tuberc Res Treat (2012)

Peritoneal tuberculosis. Numerous granulomas on the abdominal aspect of the diaphragm.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539372&req=5

fig2: Peritoneal tuberculosis. Numerous granulomas on the abdominal aspect of the diaphragm.
Mentions: Of the 153 cases of tuberculosis in our autopsy series, 24 (15.6%) patients had intestinal or peritoneal tuberculous disease. All of them had clinical manifestations consistent with the disease. Intestinal disease was present in 17 (71%), 14 of them with peritoneal involvement. Seven cases (29%) had peritoneal tuberculosis without presence of intestinal disease (isolated peritoneal disease). Most cases occurred before the year 2000, and none of our cases was associated with AIDS [17].

Bottom Line: Infection by Mycobacterium bovis is not infrequently identified in Mexico.Its relation to nonpasteurized milk products ingestion is well recognized with primary infection usually in the intestinal tract.The clinical differentiation of these conditions is difficult.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, National Institute of Pediatrics, 04530 Mexico City, DF, Mexico.

ABSTRACT
Infection by Mycobacterium bovis is not infrequently identified in Mexico. Its relation to nonpasteurized milk products ingestion is well recognized with primary infection usually in the intestinal tract. The term "abdominal tuberculosis" includes peritoneal as well as primary and secondary intestinal tuberculosis. The clinical differentiation of these conditions is difficult. In this work, we reviewed the clinical and pathological features of 24 cases of children dying with tuberculosis in whom autopsy revealed abdominal disease in a referral hospital in Mexico City. We identified 8 cases of primary intestinal tuberculosis, with documentation of M. bovis in 6 of them, and 9 cases of secondary intestinal tuberculosis (primary pulmonary disease), all negative to M. bovis. Seven patients had peritoneal tuberculosis without intestinal lesions and with active pulmonary disease in 4 of them, and of the remaining three, two had mesenteric lymph node involvement suggesting healed intestinal disease. In this approach to abdominal tuberculosis, postmortem analysis was able to differentiate primary from secondary intestinal tuberculosis and to define the nature of peritoneal involvement. This discrimination gives rise to different diagnostic approaches and epidemiological and preventive actions, particularly in countries where tuberculosis is endemic and infection by M. bovis continues to be identified.

No MeSH data available.


Related in: MedlinePlus