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Grover's Disease after Heart Transplantation: A Case Report.

Ippoliti G, Paulli M, Lucioni M, D'Armini AM, Lauriola M, Mahrous Haleem Saaleb R - Case Rep Transplant (2012)

Bottom Line: Grover's disease is a transient acantholytic dermatosis of unknown cause, manifesting clinically as a papular skin eruption that is usually located on the anterior chest and abdomen.Histologically characterized by an acantholytic pattern, it has been associated with numerous disorders, including hematologic malignancies, chronic renal failure, and HIV infection, as well as with chemotherapy and bone marrow and/or kidney transplant.Evaluation of followup and treatment is often complicated by spontaneous remission and the occasionally fluctuant course of the disease.

View Article: PubMed Central - PubMed

Affiliation: Division of Cardiac Surgery, IRCCS San Matteo Hospital Foundation, University of Pavia School of Medicine, 27100 Pavia, Italy ; U.O. Medicina Interna, Policlinico di Monza, Monza, Italy.

ABSTRACT
Grover's disease is a transient acantholytic dermatosis of unknown cause, manifesting clinically as a papular skin eruption that is usually located on the anterior chest and abdomen. Histologically characterized by an acantholytic pattern, it has been associated with numerous disorders, including hematologic malignancies, chronic renal failure, and HIV infection, as well as with chemotherapy and bone marrow and/or kidney transplant. Evaluation of followup and treatment is often complicated by spontaneous remission and the occasionally fluctuant course of the disease. Here we report the case of a patient with sudden onset of Grover's disease after heart transplantation. To the best of our knowledge, this is the first observation of Grover's disease as diagnosed after heart transplantation.

No MeSH data available.


Related in: MedlinePlus

Extensive eruption of erythematous red-brown papulovesicles lesions scattered over the abdomen and the lower extremities.
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Related In: Results  -  Collection


getmorefigures.php?uid=PMC3539346&req=5

fig1: Extensive eruption of erythematous red-brown papulovesicles lesions scattered over the abdomen and the lower extremities.

Mentions: A 64-year-old man was hospitalized at our institution with a one-month history of mildly pruritic skin lesions located on the abdomen and the lower extremities. Physical examination revealed numerous erythematous red-brown papulovesicles (Figure 1).


Grover's Disease after Heart Transplantation: A Case Report.

Ippoliti G, Paulli M, Lucioni M, D'Armini AM, Lauriola M, Mahrous Haleem Saaleb R - Case Rep Transplant (2012)

Extensive eruption of erythematous red-brown papulovesicles lesions scattered over the abdomen and the lower extremities.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3539346&req=5

fig1: Extensive eruption of erythematous red-brown papulovesicles lesions scattered over the abdomen and the lower extremities.
Mentions: A 64-year-old man was hospitalized at our institution with a one-month history of mildly pruritic skin lesions located on the abdomen and the lower extremities. Physical examination revealed numerous erythematous red-brown papulovesicles (Figure 1).

Bottom Line: Grover's disease is a transient acantholytic dermatosis of unknown cause, manifesting clinically as a papular skin eruption that is usually located on the anterior chest and abdomen.Histologically characterized by an acantholytic pattern, it has been associated with numerous disorders, including hematologic malignancies, chronic renal failure, and HIV infection, as well as with chemotherapy and bone marrow and/or kidney transplant.Evaluation of followup and treatment is often complicated by spontaneous remission and the occasionally fluctuant course of the disease.

View Article: PubMed Central - PubMed

Affiliation: Division of Cardiac Surgery, IRCCS San Matteo Hospital Foundation, University of Pavia School of Medicine, 27100 Pavia, Italy ; U.O. Medicina Interna, Policlinico di Monza, Monza, Italy.

ABSTRACT
Grover's disease is a transient acantholytic dermatosis of unknown cause, manifesting clinically as a papular skin eruption that is usually located on the anterior chest and abdomen. Histologically characterized by an acantholytic pattern, it has been associated with numerous disorders, including hematologic malignancies, chronic renal failure, and HIV infection, as well as with chemotherapy and bone marrow and/or kidney transplant. Evaluation of followup and treatment is often complicated by spontaneous remission and the occasionally fluctuant course of the disease. Here we report the case of a patient with sudden onset of Grover's disease after heart transplantation. To the best of our knowledge, this is the first observation of Grover's disease as diagnosed after heart transplantation.

No MeSH data available.


Related in: MedlinePlus