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Development of the DVH management software for the biologically-guided evaluation of radiotherapy plan.

Kim B, Park HC, Oh D, Shin EH, Ahn YC, Kim J, Han Y - Radiat Oncol J (2012)

Bottom Line: The graphical tool was developed to present the complication histogram derived from the pre-existing database (DVH and RP) and was implemented into the radiation treatment planning (RTP) system, Pinnacle(3) v8.0 (Phillips Healthcare).The software was designed for the pre-existing database to be updated easily by tagging the specific DVH data with the new incidence of RP events at the time of patients' follow-up.We developed the DVH management software as an effective tool to incorporate the phenomenological consequences derived from the pre-existing database in the evaluation of a new RT plan.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

ABSTRACT

Purpose: To develop the dose volume histogram (DVH) management software which guides the evaluation of radiotherapy (RT) plan of a new case according to the biological consequences of the DVHs from the previously treated patients.

Materials and methods: We determined the radiation pneumonitis (RP) as an biological response parameter in order to develop DVH management software. We retrospectively reviewed the medical records of lung cancer patients treated with curative 3-dimensional conformal radiation therapy (3D-CRT). The biological event was defined as RP of the Radiation Therapy Oncology Group (RTOG) grade III or more.

Results: The DVH management software consisted of three parts (pre-existing DVH database, graphical tool, and Pinnacle(3) script). The pre-existing DVH data were retrieved from 128 patients. RP events were tagged to the specific DVH data through retrospective review of patients' medical records. The graphical tool was developed to present the complication histogram derived from the pre-existing database (DVH and RP) and was implemented into the radiation treatment planning (RTP) system, Pinnacle(3) v8.0 (Phillips Healthcare). The software was designed for the pre-existing database to be updated easily by tagging the specific DVH data with the new incidence of RP events at the time of patients' follow-up.

Conclusion: We developed the DVH management software as an effective tool to incorporate the phenomenological consequences derived from the pre-existing database in the evaluation of a new RT plan. It can be used not only for lung cancer patients but also for the other disease site with different toxicity parameters.

No MeSH data available.


Related in: MedlinePlus

The structure of the dose volume histogram (DVH) management software. It consists of 3 parts and also needs adding new patient's data and update of the incidence of radiation pneumonitis (RP).
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Figure 1: The structure of the dose volume histogram (DVH) management software. It consists of 3 parts and also needs adding new patient's data and update of the incidence of radiation pneumonitis (RP).

Mentions: We designed a software consisted of three parts (pre-existing DVH database, graphical tool, and Pinnacle3 script) (Fig. 1). That would be implemented into a RTP system, Pinnacle3 v8.0 (Phillips Healthcare, Andover, MA, USA). The software accumulates the patients' DVHs that shall be conveniently sorted according to the tags of RP events evaluated at the time of follow-up for each individual patient.


Development of the DVH management software for the biologically-guided evaluation of radiotherapy plan.

Kim B, Park HC, Oh D, Shin EH, Ahn YC, Kim J, Han Y - Radiat Oncol J (2012)

The structure of the dose volume histogram (DVH) management software. It consists of 3 parts and also needs adding new patient's data and update of the incidence of radiation pneumonitis (RP).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3475962&req=5

Figure 1: The structure of the dose volume histogram (DVH) management software. It consists of 3 parts and also needs adding new patient's data and update of the incidence of radiation pneumonitis (RP).
Mentions: We designed a software consisted of three parts (pre-existing DVH database, graphical tool, and Pinnacle3 script) (Fig. 1). That would be implemented into a RTP system, Pinnacle3 v8.0 (Phillips Healthcare, Andover, MA, USA). The software accumulates the patients' DVHs that shall be conveniently sorted according to the tags of RP events evaluated at the time of follow-up for each individual patient.

Bottom Line: The graphical tool was developed to present the complication histogram derived from the pre-existing database (DVH and RP) and was implemented into the radiation treatment planning (RTP) system, Pinnacle(3) v8.0 (Phillips Healthcare).The software was designed for the pre-existing database to be updated easily by tagging the specific DVH data with the new incidence of RP events at the time of patients' follow-up.We developed the DVH management software as an effective tool to incorporate the phenomenological consequences derived from the pre-existing database in the evaluation of a new RT plan.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

ABSTRACT

Purpose: To develop the dose volume histogram (DVH) management software which guides the evaluation of radiotherapy (RT) plan of a new case according to the biological consequences of the DVHs from the previously treated patients.

Materials and methods: We determined the radiation pneumonitis (RP) as an biological response parameter in order to develop DVH management software. We retrospectively reviewed the medical records of lung cancer patients treated with curative 3-dimensional conformal radiation therapy (3D-CRT). The biological event was defined as RP of the Radiation Therapy Oncology Group (RTOG) grade III or more.

Results: The DVH management software consisted of three parts (pre-existing DVH database, graphical tool, and Pinnacle(3) script). The pre-existing DVH data were retrieved from 128 patients. RP events were tagged to the specific DVH data through retrospective review of patients' medical records. The graphical tool was developed to present the complication histogram derived from the pre-existing database (DVH and RP) and was implemented into the radiation treatment planning (RTP) system, Pinnacle(3) v8.0 (Phillips Healthcare). The software was designed for the pre-existing database to be updated easily by tagging the specific DVH data with the new incidence of RP events at the time of patients' follow-up.

Conclusion: We developed the DVH management software as an effective tool to incorporate the phenomenological consequences derived from the pre-existing database in the evaluation of a new RT plan. It can be used not only for lung cancer patients but also for the other disease site with different toxicity parameters.

No MeSH data available.


Related in: MedlinePlus