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Extra-gastrointestinal stromal tumor of the omentum: a rare case report and review of the literature.

Fagkrezos D, Touloumis Z, Giannila M, Penlidis C, Papaparaskeva K, Triantopoulou C - Rare Tumors (2012)

Bottom Line: Clinical course and the prognostic factors of such lesions will also be discussed.In most cases, a pre-operative diagnosis is not possible, and the patient undergoes a surgical operation for the generic diagnosis of abdominal mass.During the intervention it is important to achieve a complete removal of the mass and to examine every possible adhesion to the gastrointestinal wall.

View Article: PubMed Central - PubMed

Affiliation: Radiology Department, Konstantopouleio General Hospital, Aghias Olgas;

ABSTRACT
Gastrointestinal stromal tumors (GIST) are uncommon mesenchymal spindle-cell or epithelioid neoplasms, located mainly with higher frequency in the stomach and small bowel. GISTs represent the majority of primary non-epithelial neoplasms of the digestive tract, most frequently expressing the KIT protein a transmembrane tyrosine kinase receptor for stem cell factor. Extra-gastrointestinal stromal tumors tend to present In fewer than 5% of cases; they originate primarily from the mesentery, omentum or peritoneum. Furthermore, these extra-gastrointestinal tumors (EGIST) tend to be more common in patients over the age of 50 years. EGISTs are neoplasms with overlapping immunohistological features, occurring in the abdomen outside the gastrointestinal tract with no connection to the gastric or intestinal wall. We describe here a rare case of EGIST of the lesser omentum and report the clinical, macroscopic, immunohistological and radiological features of an EGIST arising in the lesser omentum of a 63-year old man. Clinical course and the prognostic factors of such lesions will also be discussed. EGISTs in the lesser omentum can grow slowly and remain silent despite a large tumor size. In most cases, a pre-operative diagnosis is not possible, and the patient undergoes a surgical operation for the generic diagnosis of abdominal mass. During the intervention it is important to achieve a complete removal of the mass and to examine every possible adhesion to the gastrointestinal wall.

No MeSH data available.


Related in: MedlinePlus

Axial computed tomography contrast ehnanced.
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Related In: Results  -  Collection


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Figure 2: Axial computed tomography contrast ehnanced.

Mentions: Blood tests revealed a severe leukocytosis (white blood cell 37300/86.2%), jaundice (Tbil 7.14 mg/dL, Dbil 6.75 mg/dL) and abnormal values of APTT (55.8 sec, INR: 1.71). Ultrasonography showed a hypoechogenic mass located between the stomach and the pancreas, adjacent to the left liver lobe, and also diffuse dilatation of the intrahepatic biliary ducts and the common bile duct. Contrast-enhanced computed tomography (CT) was performed for initial staging. CT showed a large mass (16×16×12 cm) with solid and cystic components (Figure 1). The adjacent structures including the mesenteric fat plane, the gastrohepatic ligament and the duodenum were displaced, and the mass was in contact with the stomach. The central area of the mass was of low density corresponding to cystic and necrotic components (Figure 2).


Extra-gastrointestinal stromal tumor of the omentum: a rare case report and review of the literature.

Fagkrezos D, Touloumis Z, Giannila M, Penlidis C, Papaparaskeva K, Triantopoulou C - Rare Tumors (2012)

Axial computed tomography contrast ehnanced.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3475951&req=5

Figure 2: Axial computed tomography contrast ehnanced.
Mentions: Blood tests revealed a severe leukocytosis (white blood cell 37300/86.2%), jaundice (Tbil 7.14 mg/dL, Dbil 6.75 mg/dL) and abnormal values of APTT (55.8 sec, INR: 1.71). Ultrasonography showed a hypoechogenic mass located between the stomach and the pancreas, adjacent to the left liver lobe, and also diffuse dilatation of the intrahepatic biliary ducts and the common bile duct. Contrast-enhanced computed tomography (CT) was performed for initial staging. CT showed a large mass (16×16×12 cm) with solid and cystic components (Figure 1). The adjacent structures including the mesenteric fat plane, the gastrohepatic ligament and the duodenum were displaced, and the mass was in contact with the stomach. The central area of the mass was of low density corresponding to cystic and necrotic components (Figure 2).

Bottom Line: Clinical course and the prognostic factors of such lesions will also be discussed.In most cases, a pre-operative diagnosis is not possible, and the patient undergoes a surgical operation for the generic diagnosis of abdominal mass.During the intervention it is important to achieve a complete removal of the mass and to examine every possible adhesion to the gastrointestinal wall.

View Article: PubMed Central - PubMed

Affiliation: Radiology Department, Konstantopouleio General Hospital, Aghias Olgas;

ABSTRACT
Gastrointestinal stromal tumors (GIST) are uncommon mesenchymal spindle-cell or epithelioid neoplasms, located mainly with higher frequency in the stomach and small bowel. GISTs represent the majority of primary non-epithelial neoplasms of the digestive tract, most frequently expressing the KIT protein a transmembrane tyrosine kinase receptor for stem cell factor. Extra-gastrointestinal stromal tumors tend to present In fewer than 5% of cases; they originate primarily from the mesentery, omentum or peritoneum. Furthermore, these extra-gastrointestinal tumors (EGIST) tend to be more common in patients over the age of 50 years. EGISTs are neoplasms with overlapping immunohistological features, occurring in the abdomen outside the gastrointestinal tract with no connection to the gastric or intestinal wall. We describe here a rare case of EGIST of the lesser omentum and report the clinical, macroscopic, immunohistological and radiological features of an EGIST arising in the lesser omentum of a 63-year old man. Clinical course and the prognostic factors of such lesions will also be discussed. EGISTs in the lesser omentum can grow slowly and remain silent despite a large tumor size. In most cases, a pre-operative diagnosis is not possible, and the patient undergoes a surgical operation for the generic diagnosis of abdominal mass. During the intervention it is important to achieve a complete removal of the mass and to examine every possible adhesion to the gastrointestinal wall.

No MeSH data available.


Related in: MedlinePlus