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It is short-but so what!

Arora A, Sandip S, Mukund A, Patidar Y - Indian J Endocrinol Metab (2012)

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Affiliation: Department of Radiodiagnosis, Institute of Liver and Biliary Sciences, New Delhi, India.

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There was no history of any significant past illness or abdominal surgery... His laboratory test results revealed hemoglobin 12.9 g/dl; total leukocyte count 13 200 cells/mm (neutrophils-63%); normal liver and kidney function tests... Agenesis of the dorsal pancreas is a rare congenital anomaly that represents embryological failure of the dorsal pancreatic bud to form the body and tail of the pancreas... The embryogenesis of pancreas is complex as the gland develops from the endoderm-lined dorsal and ventral buds of the duodenum... As many as 50% of the affected individuals have hyperglycemia which has been attributed to the bulk of the insulin-producing beta cells being located in the dorsal part of the gland... The diagnosis is usually suggested on cross-sectional imaging and it manifests as a short truncated pancreas with absent pancreatic parenchyma ventral to the splenic vein... It is crucial to distinguish agenesis of the pancreas from atrophy and lipomatous replacement of the pancreas secondary to chronic pancreatitis... Dependent stomach and/or dependent intestine signs on cross- sectional imaging allow differentiation of the two... The dependent stomach or dependent intestine sign refers to the distal pancreatic bed getting filled by stomach or intestines which abut the splenic vein [Figure 2a], while in case of distal lipomatosis, abundant fat tissue is observed anterior to the splenic vein and hence the bowel fails to abut the splenic vein [Figure 2b].

No MeSH data available.


CT sections through the abdomen reveal normal size head, neck and the uncinate process of the pancreas with absent pancreatic body and tail
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Figure 1: CT sections through the abdomen reveal normal size head, neck and the uncinate process of the pancreas with absent pancreatic body and tail

Mentions: A 34-year-old male presented with gradually worsening right upper-quadrant pain. There was no history of any significant past illness or abdominal surgery. His laboratory test results revealed hemoglobin 12.9 g/dl; total leukocyte count 13 200 cells/mm3 (neutrophils-63%); normal liver and kidney function tests. Ultrasound of the abdomen revealed features suggesting acute-on-chronic cholecystitis following which the patient was subjected to contrast-enhanced CT. Apart from calculus cholecystitis, an important incidental finding was detected. CT sections through the pancreas revealed normal size head, neck and the uncinate process of the pancreas with absent pancreatic body and tail. The distal pancreatic bed was seen filled by stomach and intestine [Figure 1]. The patient was subsequently evaluated and was found to have mildly elevated serum glucose (fasting blood glucose – 105 mg/ dl).


It is short-but so what!

Arora A, Sandip S, Mukund A, Patidar Y - Indian J Endocrinol Metab (2012)

CT sections through the abdomen reveal normal size head, neck and the uncinate process of the pancreas with absent pancreatic body and tail
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475926&req=5

Figure 1: CT sections through the abdomen reveal normal size head, neck and the uncinate process of the pancreas with absent pancreatic body and tail
Mentions: A 34-year-old male presented with gradually worsening right upper-quadrant pain. There was no history of any significant past illness or abdominal surgery. His laboratory test results revealed hemoglobin 12.9 g/dl; total leukocyte count 13 200 cells/mm3 (neutrophils-63%); normal liver and kidney function tests. Ultrasound of the abdomen revealed features suggesting acute-on-chronic cholecystitis following which the patient was subjected to contrast-enhanced CT. Apart from calculus cholecystitis, an important incidental finding was detected. CT sections through the pancreas revealed normal size head, neck and the uncinate process of the pancreas with absent pancreatic body and tail. The distal pancreatic bed was seen filled by stomach and intestine [Figure 1]. The patient was subsequently evaluated and was found to have mildly elevated serum glucose (fasting blood glucose – 105 mg/ dl).

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis, Institute of Liver and Biliary Sciences, New Delhi, India.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

There was no history of any significant past illness or abdominal surgery... His laboratory test results revealed hemoglobin 12.9 g/dl; total leukocyte count 13 200 cells/mm (neutrophils-63%); normal liver and kidney function tests... Agenesis of the dorsal pancreas is a rare congenital anomaly that represents embryological failure of the dorsal pancreatic bud to form the body and tail of the pancreas... The embryogenesis of pancreas is complex as the gland develops from the endoderm-lined dorsal and ventral buds of the duodenum... As many as 50% of the affected individuals have hyperglycemia which has been attributed to the bulk of the insulin-producing beta cells being located in the dorsal part of the gland... The diagnosis is usually suggested on cross-sectional imaging and it manifests as a short truncated pancreas with absent pancreatic parenchyma ventral to the splenic vein... It is crucial to distinguish agenesis of the pancreas from atrophy and lipomatous replacement of the pancreas secondary to chronic pancreatitis... Dependent stomach and/or dependent intestine signs on cross- sectional imaging allow differentiation of the two... The dependent stomach or dependent intestine sign refers to the distal pancreatic bed getting filled by stomach or intestines which abut the splenic vein [Figure 2a], while in case of distal lipomatosis, abundant fat tissue is observed anterior to the splenic vein and hence the bowel fails to abut the splenic vein [Figure 2b].

No MeSH data available.