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Oral manifestations in type-2 diabetes and related complications.

Bajaj S, Prasad S, Gupta A, Singh VB - Indian J Endocrinol Metab (2012)

Bottom Line: Fasting [(FBG) (P = 0.003)] and postprandial blood glucose [(PPBG) (P = 0.0003)] levels were significantly higher among cases.The P values for neuropathy, retinopathy, nephropathy, cardiovascular disease, dyslipidemia, and sepsis were 0.0156, 0.0241, 0.68, 0.4047, 0.0278, and 0.3149, respectively, which were significant for neuropathy, retinopathy, and dyslipidemia.Several oral complications are seen among diabetics.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, MLN Medical College, Allahabad, Uttar Pradesh, India.

ABSTRACT

Background: Knowledge of the wide spectrum of the oral markers of diabetes is imperative as one frequently encounters individuals with undetected, untreated or poorly controlled diabetes.

Objectives: The objective was to study the oral manifestations in type 2 diabetes mellitus (DM) and to establish an association between oral manifestations and associated microvascular and macrovascular complications.

Materials and methods: 50 cases of DM were selected who had oral complications. The control group comprised 50 age- and sex-matched diabetic patients without any oral complications.

Results: Oral manifestations in DM included periodontal disease in 34%, oral candidiasis in 24%, tooth loss in 24%, oral mucosal ulcers in 22%, taste impairment in 20%, xerostomia and salivary gland hypofunction in 14%, dental caries in 24%, and burning mouth sensation in 10% cases. Fasting [(FBG) (P = 0.003)] and postprandial blood glucose [(PPBG) (P = 0.0003)] levels were significantly higher among cases. The P values for neuropathy, retinopathy, nephropathy, cardiovascular disease, dyslipidemia, and sepsis were 0.0156, 0.0241, 0.68, 0.4047, 0.0278, and 0.3149, respectively, which were significant for neuropathy, retinopathy, and dyslipidemia.

Conclusions: Several oral complications are seen among diabetics. Association of oral markers in DM and microvascular complications suggests that there is a significant association between the two.

No MeSH data available.


Related in: MedlinePlus

Comparison of complications of diabetes mellitus in cases versus controls
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Figure 1: Comparison of complications of diabetes mellitus in cases versus controls

Mentions: Cases having complications of diabetes like diabetic neuropathy, diabetic retinopathy, diabetic nephropathy, cardiovascular diseases, dyslipidemia, and sepsis were 68%, 50%, 46%, 40%, 62%, and 10%, respectively [Figure 1]. The P values for neuropathy, retinopathy, and dyslipidemia were 0.0156, 0.0241, and 0.0278, respectively which were found to be significant. The P value for nephropathy was 0.68, cardiovascular disease 0.4047, and sepsis 0.3149; hence no significant association was seen between these complications and oral manifestations of diabetes. Complications of diabetes were most commonly associated with periodontal disease.


Oral manifestations in type-2 diabetes and related complications.

Bajaj S, Prasad S, Gupta A, Singh VB - Indian J Endocrinol Metab (2012)

Comparison of complications of diabetes mellitus in cases versus controls
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475903&req=5

Figure 1: Comparison of complications of diabetes mellitus in cases versus controls
Mentions: Cases having complications of diabetes like diabetic neuropathy, diabetic retinopathy, diabetic nephropathy, cardiovascular diseases, dyslipidemia, and sepsis were 68%, 50%, 46%, 40%, 62%, and 10%, respectively [Figure 1]. The P values for neuropathy, retinopathy, and dyslipidemia were 0.0156, 0.0241, and 0.0278, respectively which were found to be significant. The P value for nephropathy was 0.68, cardiovascular disease 0.4047, and sepsis 0.3149; hence no significant association was seen between these complications and oral manifestations of diabetes. Complications of diabetes were most commonly associated with periodontal disease.

Bottom Line: Fasting [(FBG) (P = 0.003)] and postprandial blood glucose [(PPBG) (P = 0.0003)] levels were significantly higher among cases.The P values for neuropathy, retinopathy, nephropathy, cardiovascular disease, dyslipidemia, and sepsis were 0.0156, 0.0241, 0.68, 0.4047, 0.0278, and 0.3149, respectively, which were significant for neuropathy, retinopathy, and dyslipidemia.Several oral complications are seen among diabetics.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, MLN Medical College, Allahabad, Uttar Pradesh, India.

ABSTRACT

Background: Knowledge of the wide spectrum of the oral markers of diabetes is imperative as one frequently encounters individuals with undetected, untreated or poorly controlled diabetes.

Objectives: The objective was to study the oral manifestations in type 2 diabetes mellitus (DM) and to establish an association between oral manifestations and associated microvascular and macrovascular complications.

Materials and methods: 50 cases of DM were selected who had oral complications. The control group comprised 50 age- and sex-matched diabetic patients without any oral complications.

Results: Oral manifestations in DM included periodontal disease in 34%, oral candidiasis in 24%, tooth loss in 24%, oral mucosal ulcers in 22%, taste impairment in 20%, xerostomia and salivary gland hypofunction in 14%, dental caries in 24%, and burning mouth sensation in 10% cases. Fasting [(FBG) (P = 0.003)] and postprandial blood glucose [(PPBG) (P = 0.0003)] levels were significantly higher among cases. The P values for neuropathy, retinopathy, nephropathy, cardiovascular disease, dyslipidemia, and sepsis were 0.0156, 0.0241, 0.68, 0.4047, 0.0278, and 0.3149, respectively, which were significant for neuropathy, retinopathy, and dyslipidemia.

Conclusions: Several oral complications are seen among diabetics. Association of oral markers in DM and microvascular complications suggests that there is a significant association between the two.

No MeSH data available.


Related in: MedlinePlus