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Low renin hypertension.

Sahay M, Sahay RK - Indian J Endocrinol Metab (2012)

Bottom Line: Low renin hypertension is an important and often underdiagnosed cause of hypertension.It may be associated with high aldosterone levels as in Conn's syndrome or low aldosterone levels as in Liddle syndrome, and syndrome of apparent mineralocorticoid excess, glucocorticoid remediable hypertension etc.Some forms of essential hypertension are also associated with low renin levels.

View Article: PubMed Central - PubMed

Affiliation: Deparment of Nephrology, Osmania General Hospital, Hyderabad, Andhra Pradesh, India.

ABSTRACT
Low renin hypertension is an important and often underdiagnosed cause of hypertension. It may be associated with high aldosterone levels as in Conn's syndrome or low aldosterone levels as in Liddle syndrome, and syndrome of apparent mineralocorticoid excess, glucocorticoid remediable hypertension etc. Some forms of essential hypertension are also associated with low renin levels. Hypokalemia may be an important finding in low renin hypertension. The aldosterone to renin ratio helps in correct diagnosis. The treatment varies with etiology hence an accurate diagnosis is essential. Aldosterone antagonists play an important role in medical management of some varieties of low renin hypertension.

No MeSH data available.


Related in: MedlinePlus

Workup for primary hyperaldosteronism
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Figure 1: Workup for primary hyperaldosteronism

Mentions: These are two other forms of primary aldosteronism associated with adrenal hyperplasia: familial hyperaldosteronism type I and type II [Figure 1]. Both are rare disorders characterized by autosomal dominant inheritance. The 2008 Endocrine Society Guidelines recommend genetic testing for familial disease in patients with primary aldosteronism, who are younger than age 20 years, or who have a family history of primary aldosteronism or stroke at a young age (<40 years). Familial hyperaldosteronism can be categorized into the following two types:


Low renin hypertension.

Sahay M, Sahay RK - Indian J Endocrinol Metab (2012)

Workup for primary hyperaldosteronism
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475896&req=5

Figure 1: Workup for primary hyperaldosteronism
Mentions: These are two other forms of primary aldosteronism associated with adrenal hyperplasia: familial hyperaldosteronism type I and type II [Figure 1]. Both are rare disorders characterized by autosomal dominant inheritance. The 2008 Endocrine Society Guidelines recommend genetic testing for familial disease in patients with primary aldosteronism, who are younger than age 20 years, or who have a family history of primary aldosteronism or stroke at a young age (<40 years). Familial hyperaldosteronism can be categorized into the following two types:

Bottom Line: Low renin hypertension is an important and often underdiagnosed cause of hypertension.It may be associated with high aldosterone levels as in Conn's syndrome or low aldosterone levels as in Liddle syndrome, and syndrome of apparent mineralocorticoid excess, glucocorticoid remediable hypertension etc.Some forms of essential hypertension are also associated with low renin levels.

View Article: PubMed Central - PubMed

Affiliation: Deparment of Nephrology, Osmania General Hospital, Hyderabad, Andhra Pradesh, India.

ABSTRACT
Low renin hypertension is an important and often underdiagnosed cause of hypertension. It may be associated with high aldosterone levels as in Conn's syndrome or low aldosterone levels as in Liddle syndrome, and syndrome of apparent mineralocorticoid excess, glucocorticoid remediable hypertension etc. Some forms of essential hypertension are also associated with low renin levels. Hypokalemia may be an important finding in low renin hypertension. The aldosterone to renin ratio helps in correct diagnosis. The treatment varies with etiology hence an accurate diagnosis is essential. Aldosterone antagonists play an important role in medical management of some varieties of low renin hypertension.

No MeSH data available.


Related in: MedlinePlus