Limits...
Imaging of pediatric pituitary endocrinopathies.

Chaudhary V, Bano S - Indian J Endocrinol Metab (2012)

Bottom Line: Neuroimaging can be normal or disclose abnormalities related to pituitary-hypothalamic axis like (i) congenital and developmental malformations; (ii) tumors; (iii) cystic lesions; and (iv) infectious and inflammatory conditions.Classical midline anomalies like septo-optic dysplasias or corpus callosum agenesis are commonly associated with pituitary endocrinopathies and also need careful evaluation.In this radiological review, we will discuss neuroendocrine disorders related to hypothalamic pituitary-axis.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis, Employees' State Insurance Corporation (ESIC) Model Hospital, Gurgaon, Haryana, India.

ABSTRACT
Accurate investigation of the hypothalamic-pituitary area is required in pediatric patients for diagnosis of endocrine-related disorders. These disorders include hypopituitarism, growth failure, diencephalic syndrome, delayed puberty, precocious puberty, diabetes insipidus, syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and hyperpituitarism. Magnetic resonance imaging (MRI) is the modality of choice to visualize hypothalamic-pituitary axis and associated endocrinopathies. Neuroimaging can be normal or disclose abnormalities related to pituitary-hypothalamic axis like (i) congenital and developmental malformations; (ii) tumors; (iii) cystic lesions; and (iv) infectious and inflammatory conditions. Classical midline anomalies like septo-optic dysplasias or corpus callosum agenesis are commonly associated with pituitary endocrinopathies and also need careful evaluation. In this radiological review, we will discuss neuroendocrine disorders related to hypothalamic pituitary-axis.

No MeSH data available.


Related in: MedlinePlus

Langerhans cell histiocytosis (LCH) in a young patient with systemic LCH: Coronal FLAIR (a) image shows thickening of pituitary stalk and optic chiasma (thin white arrow) and a granulomatous mass lesion sitting on the top of optic chiasma (thin black arrow). None to minimal enhancement of the lesion is seen on T1W postcontrast image (b) Note, associated obstructive hydrocephalus.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3475890&req=5

Figure 10: Langerhans cell histiocytosis (LCH) in a young patient with systemic LCH: Coronal FLAIR (a) image shows thickening of pituitary stalk and optic chiasma (thin white arrow) and a granulomatous mass lesion sitting on the top of optic chiasma (thin black arrow). None to minimal enhancement of the lesion is seen on T1W postcontrast image (b) Note, associated obstructive hydrocephalus.

Mentions: Patients with systemic LCH may have involvement of the pituitary–hypothalamus axis. The MRI [Figure 10] may demonstrate a granulomatous mass in region of hypothalamus or thickening of pituitary stalk. There is marked enhancement of the lesion after gadolinium administration. In patients with LCH, posterior pituitary bright spot is usually absent. These imaging features correlate with the typical clinical presentation of DI.[48]


Imaging of pediatric pituitary endocrinopathies.

Chaudhary V, Bano S - Indian J Endocrinol Metab (2012)

Langerhans cell histiocytosis (LCH) in a young patient with systemic LCH: Coronal FLAIR (a) image shows thickening of pituitary stalk and optic chiasma (thin white arrow) and a granulomatous mass lesion sitting on the top of optic chiasma (thin black arrow). None to minimal enhancement of the lesion is seen on T1W postcontrast image (b) Note, associated obstructive hydrocephalus.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475890&req=5

Figure 10: Langerhans cell histiocytosis (LCH) in a young patient with systemic LCH: Coronal FLAIR (a) image shows thickening of pituitary stalk and optic chiasma (thin white arrow) and a granulomatous mass lesion sitting on the top of optic chiasma (thin black arrow). None to minimal enhancement of the lesion is seen on T1W postcontrast image (b) Note, associated obstructive hydrocephalus.
Mentions: Patients with systemic LCH may have involvement of the pituitary–hypothalamus axis. The MRI [Figure 10] may demonstrate a granulomatous mass in region of hypothalamus or thickening of pituitary stalk. There is marked enhancement of the lesion after gadolinium administration. In patients with LCH, posterior pituitary bright spot is usually absent. These imaging features correlate with the typical clinical presentation of DI.[48]

Bottom Line: Neuroimaging can be normal or disclose abnormalities related to pituitary-hypothalamic axis like (i) congenital and developmental malformations; (ii) tumors; (iii) cystic lesions; and (iv) infectious and inflammatory conditions.Classical midline anomalies like septo-optic dysplasias or corpus callosum agenesis are commonly associated with pituitary endocrinopathies and also need careful evaluation.In this radiological review, we will discuss neuroendocrine disorders related to hypothalamic pituitary-axis.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis, Employees' State Insurance Corporation (ESIC) Model Hospital, Gurgaon, Haryana, India.

ABSTRACT
Accurate investigation of the hypothalamic-pituitary area is required in pediatric patients for diagnosis of endocrine-related disorders. These disorders include hypopituitarism, growth failure, diencephalic syndrome, delayed puberty, precocious puberty, diabetes insipidus, syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and hyperpituitarism. Magnetic resonance imaging (MRI) is the modality of choice to visualize hypothalamic-pituitary axis and associated endocrinopathies. Neuroimaging can be normal or disclose abnormalities related to pituitary-hypothalamic axis like (i) congenital and developmental malformations; (ii) tumors; (iii) cystic lesions; and (iv) infectious and inflammatory conditions. Classical midline anomalies like septo-optic dysplasias or corpus callosum agenesis are commonly associated with pituitary endocrinopathies and also need careful evaluation. In this radiological review, we will discuss neuroendocrine disorders related to hypothalamic pituitary-axis.

No MeSH data available.


Related in: MedlinePlus