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Imaging of pediatric pituitary endocrinopathies.

Chaudhary V, Bano S - Indian J Endocrinol Metab (2012)

Bottom Line: Neuroimaging can be normal or disclose abnormalities related to pituitary-hypothalamic axis like (i) congenital and developmental malformations; (ii) tumors; (iii) cystic lesions; and (iv) infectious and inflammatory conditions.Classical midline anomalies like septo-optic dysplasias or corpus callosum agenesis are commonly associated with pituitary endocrinopathies and also need careful evaluation.In this radiological review, we will discuss neuroendocrine disorders related to hypothalamic pituitary-axis.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis, Employees' State Insurance Corporation (ESIC) Model Hospital, Gurgaon, Haryana, India.

ABSTRACT
Accurate investigation of the hypothalamic-pituitary area is required in pediatric patients for diagnosis of endocrine-related disorders. These disorders include hypopituitarism, growth failure, diencephalic syndrome, delayed puberty, precocious puberty, diabetes insipidus, syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and hyperpituitarism. Magnetic resonance imaging (MRI) is the modality of choice to visualize hypothalamic-pituitary axis and associated endocrinopathies. Neuroimaging can be normal or disclose abnormalities related to pituitary-hypothalamic axis like (i) congenital and developmental malformations; (ii) tumors; (iii) cystic lesions; and (iv) infectious and inflammatory conditions. Classical midline anomalies like septo-optic dysplasias or corpus callosum agenesis are commonly associated with pituitary endocrinopathies and also need careful evaluation. In this radiological review, we will discuss neuroendocrine disorders related to hypothalamic pituitary-axis.

No MeSH data available.


Related in: MedlinePlus

Hypothalamic hamartoma: Axial (a) and sagittal (b) postcontrast CT scan images of brain demonstrate a tiny, well-defined, nonenhancing rounded suprasellar mass arising from hypothalamus (arrow). Note, the lesion is isodense to normal brain parenchyma
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Figure 4: Hypothalamic hamartoma: Axial (a) and sagittal (b) postcontrast CT scan images of brain demonstrate a tiny, well-defined, nonenhancing rounded suprasellar mass arising from hypothalamus (arrow). Note, the lesion is isodense to normal brain parenchyma

Mentions: These are benign developmental masses that arise in tuber cinereum of the hypothalamus. On MRI [Figure 4], these are identified as well-defined, noninvasive rounded suprasellar mass lesions arising from hypothalamus. They are of similar signal to the gray matter and do not show contrast enhancement. Clinically, the presenting symptoms include precocious puberty, gelastic (laughing) seizures and developmental delay.[1730]


Imaging of pediatric pituitary endocrinopathies.

Chaudhary V, Bano S - Indian J Endocrinol Metab (2012)

Hypothalamic hamartoma: Axial (a) and sagittal (b) postcontrast CT scan images of brain demonstrate a tiny, well-defined, nonenhancing rounded suprasellar mass arising from hypothalamus (arrow). Note, the lesion is isodense to normal brain parenchyma
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475890&req=5

Figure 4: Hypothalamic hamartoma: Axial (a) and sagittal (b) postcontrast CT scan images of brain demonstrate a tiny, well-defined, nonenhancing rounded suprasellar mass arising from hypothalamus (arrow). Note, the lesion is isodense to normal brain parenchyma
Mentions: These are benign developmental masses that arise in tuber cinereum of the hypothalamus. On MRI [Figure 4], these are identified as well-defined, noninvasive rounded suprasellar mass lesions arising from hypothalamus. They are of similar signal to the gray matter and do not show contrast enhancement. Clinically, the presenting symptoms include precocious puberty, gelastic (laughing) seizures and developmental delay.[1730]

Bottom Line: Neuroimaging can be normal or disclose abnormalities related to pituitary-hypothalamic axis like (i) congenital and developmental malformations; (ii) tumors; (iii) cystic lesions; and (iv) infectious and inflammatory conditions.Classical midline anomalies like septo-optic dysplasias or corpus callosum agenesis are commonly associated with pituitary endocrinopathies and also need careful evaluation.In this radiological review, we will discuss neuroendocrine disorders related to hypothalamic pituitary-axis.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis, Employees' State Insurance Corporation (ESIC) Model Hospital, Gurgaon, Haryana, India.

ABSTRACT
Accurate investigation of the hypothalamic-pituitary area is required in pediatric patients for diagnosis of endocrine-related disorders. These disorders include hypopituitarism, growth failure, diencephalic syndrome, delayed puberty, precocious puberty, diabetes insipidus, syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and hyperpituitarism. Magnetic resonance imaging (MRI) is the modality of choice to visualize hypothalamic-pituitary axis and associated endocrinopathies. Neuroimaging can be normal or disclose abnormalities related to pituitary-hypothalamic axis like (i) congenital and developmental malformations; (ii) tumors; (iii) cystic lesions; and (iv) infectious and inflammatory conditions. Classical midline anomalies like septo-optic dysplasias or corpus callosum agenesis are commonly associated with pituitary endocrinopathies and also need careful evaluation. In this radiological review, we will discuss neuroendocrine disorders related to hypothalamic pituitary-axis.

No MeSH data available.


Related in: MedlinePlus