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Upper lip malignant neoplasms. A study of 59 cases.

Luna-Ortiz K, Güemes-Meza A, Villavicencio-Valencia V, Mosqueda-Taylor A - Med Oral Patol Oral Cir Bucal (2012)

Bottom Line: There were no significant differences with respect to the overall survival curve and the disease-free survival curve among surgical treatment and radiotherapy.In addition, there was not statistically significant difference in the overall survival and disease-free survival among squamous cell carcinoma and basal cell carcinoma cases with respect to the type of treatment.The present series describes the main clinico-pathological features in a hospital-based population in Mexico city and demonstrates some differences with respect to those found in the lower lip.

View Article: PubMed Central - PubMed

Affiliation: Department of Head and Neck Surgery, Instituto Nacional de Cancerología, México. kuauhyama@yahoo.com.mx

ABSTRACT

Objectives: To present the demographic data, clinico-pathologic features and therapeutic outcome of a series of upper lip malignancies.

Study design: Retrospective study at a single Cancer Institution in Mexico City during a 14-year period.

Results: There were 59 cases, (30 males and 29 females); age range: 14 to 106 years (mean: 73 yr.). Antecedents of ultraviolet light and tobacco exposure were found in 20 (33.9%) and 16 cases (27%) respectively. There were 35 squamous cell carcinomas (59.3%), 19 basal cell carcinomas (32.2%) and one case each (1.7%) of adenocarcinoma NOS, adenoid cystic carcinoma, angiosarcoma, Merkel cell carcinoma and melanoma. There were 14 cases in stage I (23.7%), 14 in stage II (23.7%), 3 in stage III (5.1%) 14 in stage IV (23.7%) and 14 were not classified (23.7%). There were no significant differences with respect to the overall survival curve and the disease-free survival curve among surgical treatment and radiotherapy. In addition, there was not statistically significant difference in the overall survival and disease-free survival among squamous cell carcinoma and basal cell carcinoma cases with respect to the type of treatment.

Conclusions: Upper lip malignant neoplasms are infrequent lesions. The present series describes the main clinico-pathological features in a hospital-based population in Mexico city and demonstrates some differences with respect to those found in the lower lip.

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A. Overall survival curve of the present series. B. Disease-free period of the present series.
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Figure 1: A. Overall survival curve of the present series. B. Disease-free period of the present series.

Mentions: There were 59 cases of upper lip malignancies. Of these, 30 (50.8%) occurred in males and 29 (49.2%) in females, with an age range from 14 to 106 years (mean: 73 yr.). The salient clinical and demographic features are shown in ( Table 1). Histopathologic diagnosis and histological grading are shown in ( Table 2), where it is shown that although SCC and BCC carcinomas accounted for more than 90% of the cases, there were five other different malignant neoplasms diagnosed. Only 46 patients were treated, and there were 4 recurrences (8.7%) and 13 persistent cases (28.3%), comprising a total of 17 cases (36.9%). Comparison among surgical treatment vs radiotherapy is shown in ( Table 3). (Fig. 1) illustrates the overall survival curve (A) and the disease-free period (B). (Fig. 2) show the overall survival curve (A) and the disease free period (B) according to primary treatment, and it was found that there were no significant differences with respect to the overall survival curve and the disease-free survival curve among both types of treatment (p=0.4947 and p=0.7492 respectively). In addition, there was not statistically significant difference in the overall survival (p=0.66) and disease-free survival (p=0.50) among squamous cell carcinoma and basal cell carcinoma cases with respect to the type of treatment (p=0.347).


Upper lip malignant neoplasms. A study of 59 cases.

Luna-Ortiz K, Güemes-Meza A, Villavicencio-Valencia V, Mosqueda-Taylor A - Med Oral Patol Oral Cir Bucal (2012)

A. Overall survival curve of the present series. B. Disease-free period of the present series.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475642&req=5

Figure 1: A. Overall survival curve of the present series. B. Disease-free period of the present series.
Mentions: There were 59 cases of upper lip malignancies. Of these, 30 (50.8%) occurred in males and 29 (49.2%) in females, with an age range from 14 to 106 years (mean: 73 yr.). The salient clinical and demographic features are shown in ( Table 1). Histopathologic diagnosis and histological grading are shown in ( Table 2), where it is shown that although SCC and BCC carcinomas accounted for more than 90% of the cases, there were five other different malignant neoplasms diagnosed. Only 46 patients were treated, and there were 4 recurrences (8.7%) and 13 persistent cases (28.3%), comprising a total of 17 cases (36.9%). Comparison among surgical treatment vs radiotherapy is shown in ( Table 3). (Fig. 1) illustrates the overall survival curve (A) and the disease-free period (B). (Fig. 2) show the overall survival curve (A) and the disease free period (B) according to primary treatment, and it was found that there were no significant differences with respect to the overall survival curve and the disease-free survival curve among both types of treatment (p=0.4947 and p=0.7492 respectively). In addition, there was not statistically significant difference in the overall survival (p=0.66) and disease-free survival (p=0.50) among squamous cell carcinoma and basal cell carcinoma cases with respect to the type of treatment (p=0.347).

Bottom Line: There were no significant differences with respect to the overall survival curve and the disease-free survival curve among surgical treatment and radiotherapy.In addition, there was not statistically significant difference in the overall survival and disease-free survival among squamous cell carcinoma and basal cell carcinoma cases with respect to the type of treatment.The present series describes the main clinico-pathological features in a hospital-based population in Mexico city and demonstrates some differences with respect to those found in the lower lip.

View Article: PubMed Central - PubMed

Affiliation: Department of Head and Neck Surgery, Instituto Nacional de Cancerología, México. kuauhyama@yahoo.com.mx

ABSTRACT

Objectives: To present the demographic data, clinico-pathologic features and therapeutic outcome of a series of upper lip malignancies.

Study design: Retrospective study at a single Cancer Institution in Mexico City during a 14-year period.

Results: There were 59 cases, (30 males and 29 females); age range: 14 to 106 years (mean: 73 yr.). Antecedents of ultraviolet light and tobacco exposure were found in 20 (33.9%) and 16 cases (27%) respectively. There were 35 squamous cell carcinomas (59.3%), 19 basal cell carcinomas (32.2%) and one case each (1.7%) of adenocarcinoma NOS, adenoid cystic carcinoma, angiosarcoma, Merkel cell carcinoma and melanoma. There were 14 cases in stage I (23.7%), 14 in stage II (23.7%), 3 in stage III (5.1%) 14 in stage IV (23.7%) and 14 were not classified (23.7%). There were no significant differences with respect to the overall survival curve and the disease-free survival curve among surgical treatment and radiotherapy. In addition, there was not statistically significant difference in the overall survival and disease-free survival among squamous cell carcinoma and basal cell carcinoma cases with respect to the type of treatment.

Conclusions: Upper lip malignant neoplasms are infrequent lesions. The present series describes the main clinico-pathological features in a hospital-based population in Mexico city and demonstrates some differences with respect to those found in the lower lip.

Show MeSH
Related in: MedlinePlus