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The national status of tuberculosis using nationwide medical records survey of patients with tuberculosis in Korea.

Park YS, Hong SJ, Boo YK, Hwang ES, Kim HJ, Cho SH, Na KI, Cho EH, Shin SS - Tuberc Respir Dis (Seoul) (2012)

Bottom Line: In terms of treatment outcomes, 66.4% of all TB patients, 70.5% of new cases, 64.4% of relapse cases, and 46.8% of MDR-TB cases were cured or completed.It was inferred that in 2008, the total number of TB patients reached 70,767, 145.6 per 100,000 people (95% confidence interval, 145.5~145.7).We conclude that the medical records review of the Health Insurance Review and Assessment Service (HIRA) data can be very effective in promoting the understanding of the current status of TB in private institutions.

View Article: PubMed Central - PubMed

Affiliation: Division of HIV and TB Control, Korea Centers for Disease Control and Prevention, Cheongwon, Korea.

ABSTRACT

Background: The epidemiology of tuberculosis (TB) has been assessed based on the data of the analysis of TB patients notified to the surveillance system in Korea. However, the national status of TB is not validated through this surveillance system. The objective is to determine the epidemiology of TB and to understand the accurate status of TB patients treated in private institutions.

Methods: Medical records of 53,579 patients who had been diagnosed with TB in 2008 were analyzed.

Results: Among 53,579 patients, the number of sputum smear positive cases was 15,639(29.2%) and the number of new cases was 39,191 (73.1%). The drug resistance rate of new cases was 5.3%, while the rate stood at 13.3% for TB patients with treatment history. The number of multi-drug resistant TB (MDR-TB) patients was 2,472 (4.6%), which consists of 2.9% of new cases and 9.3% of TB patients with prior treatment history. The number of extensively drug-resistant TB patients was 749 (1.4%), consisting of 1.1% of new cases and 2.2% of TB patients with prior treatment history. In terms of treatment outcomes, 66.4% of all TB patients, 70.5% of new cases, 64.4% of relapse cases, and 46.8% of MDR-TB cases were cured or completed. It was inferred that in 2008, the total number of TB patients reached 70,767, 145.6 per 100,000 people (95% confidence interval, 145.5~145.7).

Conclusion: We conclude that the medical records review of the Health Insurance Review and Assessment Service (HIRA) data can be very effective in promoting the understanding of the current status of TB in private institutions.

No MeSH data available.


Related in: MedlinePlus

Rate of resistance to anti TB drugs in MDR-TB and XDR-TB patient. TB: tuberculosis; MDR-TB: multi-drug resistant TB; XDR-TB: extensively drug-resistant TB.
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Figure 1: Rate of resistance to anti TB drugs in MDR-TB and XDR-TB patient. TB: tuberculosis; MDR-TB: multi-drug resistant TB; XDR-TB: extensively drug-resistant TB.

Mentions: In terms of drug-resistant TB, the number of MDR-TB patients was 2,472 (4.6%), accounting for 62.1% of all drug-resistant TB patients. Among them, 1,130 patients (2.9%) were new cases (39,191 patients) and 1,342 patients (9.3%) were TB patients with prior treatment history (14,388 patients) (Table 5). In terms of distribution of resistance to first-line TB drugs, among 2,472 MDR-TB patients, 47% were resistant to ethambutol, 45% to pyrazinamide, 41% to rifabutin. In terms of distribution of resistance to second-line injectable drugs, 38% to streptomycin, 30% to kanamycin, 22% to capreomycin, 10% to amikacin. In terms of distribution of resistance to fluoroquinolones, 36% to ofloxacin, 14% to moxifloxacin, 6% to levofloxacin (Figure 1).


The national status of tuberculosis using nationwide medical records survey of patients with tuberculosis in Korea.

Park YS, Hong SJ, Boo YK, Hwang ES, Kim HJ, Cho SH, Na KI, Cho EH, Shin SS - Tuberc Respir Dis (Seoul) (2012)

Rate of resistance to anti TB drugs in MDR-TB and XDR-TB patient. TB: tuberculosis; MDR-TB: multi-drug resistant TB; XDR-TB: extensively drug-resistant TB.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3475472&req=5

Figure 1: Rate of resistance to anti TB drugs in MDR-TB and XDR-TB patient. TB: tuberculosis; MDR-TB: multi-drug resistant TB; XDR-TB: extensively drug-resistant TB.
Mentions: In terms of drug-resistant TB, the number of MDR-TB patients was 2,472 (4.6%), accounting for 62.1% of all drug-resistant TB patients. Among them, 1,130 patients (2.9%) were new cases (39,191 patients) and 1,342 patients (9.3%) were TB patients with prior treatment history (14,388 patients) (Table 5). In terms of distribution of resistance to first-line TB drugs, among 2,472 MDR-TB patients, 47% were resistant to ethambutol, 45% to pyrazinamide, 41% to rifabutin. In terms of distribution of resistance to second-line injectable drugs, 38% to streptomycin, 30% to kanamycin, 22% to capreomycin, 10% to amikacin. In terms of distribution of resistance to fluoroquinolones, 36% to ofloxacin, 14% to moxifloxacin, 6% to levofloxacin (Figure 1).

Bottom Line: In terms of treatment outcomes, 66.4% of all TB patients, 70.5% of new cases, 64.4% of relapse cases, and 46.8% of MDR-TB cases were cured or completed.It was inferred that in 2008, the total number of TB patients reached 70,767, 145.6 per 100,000 people (95% confidence interval, 145.5~145.7).We conclude that the medical records review of the Health Insurance Review and Assessment Service (HIRA) data can be very effective in promoting the understanding of the current status of TB in private institutions.

View Article: PubMed Central - PubMed

Affiliation: Division of HIV and TB Control, Korea Centers for Disease Control and Prevention, Cheongwon, Korea.

ABSTRACT

Background: The epidemiology of tuberculosis (TB) has been assessed based on the data of the analysis of TB patients notified to the surveillance system in Korea. However, the national status of TB is not validated through this surveillance system. The objective is to determine the epidemiology of TB and to understand the accurate status of TB patients treated in private institutions.

Methods: Medical records of 53,579 patients who had been diagnosed with TB in 2008 were analyzed.

Results: Among 53,579 patients, the number of sputum smear positive cases was 15,639(29.2%) and the number of new cases was 39,191 (73.1%). The drug resistance rate of new cases was 5.3%, while the rate stood at 13.3% for TB patients with treatment history. The number of multi-drug resistant TB (MDR-TB) patients was 2,472 (4.6%), which consists of 2.9% of new cases and 9.3% of TB patients with prior treatment history. The number of extensively drug-resistant TB patients was 749 (1.4%), consisting of 1.1% of new cases and 2.2% of TB patients with prior treatment history. In terms of treatment outcomes, 66.4% of all TB patients, 70.5% of new cases, 64.4% of relapse cases, and 46.8% of MDR-TB cases were cured or completed. It was inferred that in 2008, the total number of TB patients reached 70,767, 145.6 per 100,000 people (95% confidence interval, 145.5~145.7).

Conclusion: We conclude that the medical records review of the Health Insurance Review and Assessment Service (HIRA) data can be very effective in promoting the understanding of the current status of TB in private institutions.

No MeSH data available.


Related in: MedlinePlus