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Invasive aspergillosis involving the lungs and brain after short period of steroid injection: a case report.

Choi YR, Kim JT, Kim JE, Jung HW, Choe KH, Lee KM, An JY - Tuberc Respir Dis (Seoul) (2012)

Bottom Line: Brain magnetic resonance imagining revealed numerous peripheral thin enhancing cystic nodules in both cerebral hemispheres.We initiated intravenous administration of amphotercin B.However, the patient died after nine days.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Chungbuk University College of Medicine, Cheongju, Korea.

ABSTRACT
Invasive pulmonary aspergillosis (IPA) has emerged as a severe infection in patients with immunocompromised hosts. However, recently, several IPA cases, without an apparent predisposition to immunodeficiency, has been reported. A 72-year-old woman was admitted for evaluation of general weakness and poor oral intake. She reported no medical history, except for intraarticular injection of a corticosteroid for joint pain for the duration of two months. A chest radiography revealed multiple cavitary nodules in both lungs. Examination of specimens, obtained by percutaneous needle biopsy, led to a diagnosis of invasive aspergillosis. Brain magnetic resonance imagining revealed numerous peripheral thin enhancing cystic nodules in both cerebral hemispheres. We initiated intravenous administration of amphotercin B. However, the patient died after nine days. Here, we report an invasive aspergillosis case, which involves the lungs and brain after a short period of steroid injection.

No MeSH data available.


Related in: MedlinePlus

Brain magnetic resonance imaging (MRI) findings. Brain MRI revealed numerous peripheral thin enhancing cystic nodules in right and left cerebral hemispheres.
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Figure 3: Brain magnetic resonance imaging (MRI) findings. Brain MRI revealed numerous peripheral thin enhancing cystic nodules in right and left cerebral hemispheres.

Mentions: On the third hospital day, percutaneous needle biopsy was performed for differential diagnosis of malignant metastasis and rare diseases such as fungus, vasculitis. Biopsy shows an aggregate of fungal hypae with acute angle branching and a rare fruit body (Figure 3).


Invasive aspergillosis involving the lungs and brain after short period of steroid injection: a case report.

Choi YR, Kim JT, Kim JE, Jung HW, Choe KH, Lee KM, An JY - Tuberc Respir Dis (Seoul) (2012)

Brain magnetic resonance imaging (MRI) findings. Brain MRI revealed numerous peripheral thin enhancing cystic nodules in right and left cerebral hemispheres.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3475467&req=5

Figure 3: Brain magnetic resonance imaging (MRI) findings. Brain MRI revealed numerous peripheral thin enhancing cystic nodules in right and left cerebral hemispheres.
Mentions: On the third hospital day, percutaneous needle biopsy was performed for differential diagnosis of malignant metastasis and rare diseases such as fungus, vasculitis. Biopsy shows an aggregate of fungal hypae with acute angle branching and a rare fruit body (Figure 3).

Bottom Line: Brain magnetic resonance imagining revealed numerous peripheral thin enhancing cystic nodules in both cerebral hemispheres.We initiated intravenous administration of amphotercin B.However, the patient died after nine days.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Chungbuk University College of Medicine, Cheongju, Korea.

ABSTRACT
Invasive pulmonary aspergillosis (IPA) has emerged as a severe infection in patients with immunocompromised hosts. However, recently, several IPA cases, without an apparent predisposition to immunodeficiency, has been reported. A 72-year-old woman was admitted for evaluation of general weakness and poor oral intake. She reported no medical history, except for intraarticular injection of a corticosteroid for joint pain for the duration of two months. A chest radiography revealed multiple cavitary nodules in both lungs. Examination of specimens, obtained by percutaneous needle biopsy, led to a diagnosis of invasive aspergillosis. Brain magnetic resonance imagining revealed numerous peripheral thin enhancing cystic nodules in both cerebral hemispheres. We initiated intravenous administration of amphotercin B. However, the patient died after nine days. Here, we report an invasive aspergillosis case, which involves the lungs and brain after a short period of steroid injection.

No MeSH data available.


Related in: MedlinePlus