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MtDNA analysis of global populations support that major population expansions began before Neolithic Time.

Zheng HX, Yan S, Qin ZD, Jin L - Sci Rep (2012)

Bottom Line: With the benefit of 1000 Genome Project, we were able to analyze a total of 910 samples from 11 populations in Africa, Europe and Americas.Furthermore, major population expansions were estimated after Last Glacial Maximum but before Neolithic Time, also corresponding to the result of major lineage expansions.Considering results in current and previous study, global mtDNA evidence showed that rising temperature after Last Glacial Maximum offered amiable environments and might be the most important factor for prehistorical human expansions.

View Article: PubMed Central - PubMed

Affiliation: MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

ABSTRACT
Agriculture resulted in extensive population growths and human activities. However, whether major human expansions started after Neolithic Time still remained controversial. With the benefit of 1000 Genome Project, we were able to analyze a total of 910 samples from 11 populations in Africa, Europe and Americas. From these random samples, we identified the expansion lineages and reconstructed the historical demographic variations. In all the three continents, we found that most major lineage expansions (11 out of 15 star lineages in Africa, all autochthonous lineages in Europe and America) coalesced before the first appearance of agriculture. Furthermore, major population expansions were estimated after Last Glacial Maximum but before Neolithic Time, also corresponding to the result of major lineage expansions. Considering results in current and previous study, global mtDNA evidence showed that rising temperature after Last Glacial Maximum offered amiable environments and might be the most important factor for prehistorical human expansions.

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Time estimation of each observed expansion in 5 European populations and Bayesian skyline plot for 5 European populations together.(A)Time estimation of each observed expansion in 5 European populations.(B) mtDNA Bayesian skyline plot showing size trend of the 5 European populations together, detailed setting refers to Methods. The grey area shows the time after LGM and before Neolithic Time.
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f5: Time estimation of each observed expansion in 5 European populations and Bayesian skyline plot for 5 European populations together.(A)Time estimation of each observed expansion in 5 European populations.(B) mtDNA Bayesian skyline plot showing size trend of the 5 European populations together, detailed setting refers to Methods. The grey area shows the time after LGM and before Neolithic Time.

Mentions: From the European BSP plots (Figure 2), 3 populations (CEU, FIN and TSI) were found that they began distinct growth ~14−12 kya, which were concordant to previous analysis in Middle East21. As expected, from the BSP plot including all European samples in Macrohaplogroup N (Figure 5B), we found that the expansion began ~ 13 kya and showed a continuous trend to nowadays, which is very similar to the result of BSP analysis of East Asian14. The population expansion began ~ 13 kya might correlate to lineages H1, H3, J1c, J1c3, K1, T1, U5a1, V and W.


MtDNA analysis of global populations support that major population expansions began before Neolithic Time.

Zheng HX, Yan S, Qin ZD, Jin L - Sci Rep (2012)

Time estimation of each observed expansion in 5 European populations and Bayesian skyline plot for 5 European populations together.(A)Time estimation of each observed expansion in 5 European populations.(B) mtDNA Bayesian skyline plot showing size trend of the 5 European populations together, detailed setting refers to Methods. The grey area shows the time after LGM and before Neolithic Time.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475341&req=5

f5: Time estimation of each observed expansion in 5 European populations and Bayesian skyline plot for 5 European populations together.(A)Time estimation of each observed expansion in 5 European populations.(B) mtDNA Bayesian skyline plot showing size trend of the 5 European populations together, detailed setting refers to Methods. The grey area shows the time after LGM and before Neolithic Time.
Mentions: From the European BSP plots (Figure 2), 3 populations (CEU, FIN and TSI) were found that they began distinct growth ~14−12 kya, which were concordant to previous analysis in Middle East21. As expected, from the BSP plot including all European samples in Macrohaplogroup N (Figure 5B), we found that the expansion began ~ 13 kya and showed a continuous trend to nowadays, which is very similar to the result of BSP analysis of East Asian14. The population expansion began ~ 13 kya might correlate to lineages H1, H3, J1c, J1c3, K1, T1, U5a1, V and W.

Bottom Line: With the benefit of 1000 Genome Project, we were able to analyze a total of 910 samples from 11 populations in Africa, Europe and Americas.Furthermore, major population expansions were estimated after Last Glacial Maximum but before Neolithic Time, also corresponding to the result of major lineage expansions.Considering results in current and previous study, global mtDNA evidence showed that rising temperature after Last Glacial Maximum offered amiable environments and might be the most important factor for prehistorical human expansions.

View Article: PubMed Central - PubMed

Affiliation: MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

ABSTRACT
Agriculture resulted in extensive population growths and human activities. However, whether major human expansions started after Neolithic Time still remained controversial. With the benefit of 1000 Genome Project, we were able to analyze a total of 910 samples from 11 populations in Africa, Europe and Americas. From these random samples, we identified the expansion lineages and reconstructed the historical demographic variations. In all the three continents, we found that most major lineage expansions (11 out of 15 star lineages in Africa, all autochthonous lineages in Europe and America) coalesced before the first appearance of agriculture. Furthermore, major population expansions were estimated after Last Glacial Maximum but before Neolithic Time, also corresponding to the result of major lineage expansions. Considering results in current and previous study, global mtDNA evidence showed that rising temperature after Last Glacial Maximum offered amiable environments and might be the most important factor for prehistorical human expansions.

Show MeSH
Related in: MedlinePlus