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Alveolar echinococcosis of the liver: report of three cases from different geographic areas of iran.

Geramizadeh B, Nikeghbalian S, Malekhosseini SA - Hepat Mon (2012)

Bottom Line: There were three female patients, 21, 47 and 53 year-old.According to our experience, AE is not an uncommon disease in Iran.Moreover, it has a widespread epidemiology, i.e., this disease should be suspected in all provinces of Iran, not only in the northern, but also in the southern regions of the country.

View Article: PubMed Central - PubMed

Affiliation: Transplant Research Center, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran ; Department of Pathology, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran.

ABSTRACT

Introduction: Alveolar echinococcosis (AE) is a chronic, serious and sometimes lethal parasitic infection, which is caused by Echinococcus multilocularis (EM). AE has been reported to occur in people from the north of Iran; however, until now there have been no cases of AE reportedfrom the southern provinces, such as Khuzestan.

Case presentation: Herein, we report our experiences with three cases of hepatic AE, who presented with large masses in the liver, from both the northern and southern provinces of Iran. Three patients are described who were presented with hepatic masses from different provinces of the country.

Conclusions: There were three female patients, 21, 47 and 53 year-old. They were presented with liver masses from different centers of the country i.e. Khorasan, Ardabil and Khuzestan. According to our experience, AE is not an uncommon disease in Iran. Moreover, it has a widespread epidemiology, i.e., this disease should be suspected in all provinces of Iran, not only in the northern, but also in the southern regions of the country.

No MeSH data available.


Related in: MedlinePlus

CT Scan Shows Well Defined Masses in Right Lobe of the Liver
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fig366: CT Scan Shows Well Defined Masses in Right Lobe of the Liver

Mentions: Physical examination showed icteric sclera. Heart and lung examination were unremarkable. Abdominal examination showed hepatomegaly. Laboratory findings showed; anemia, hyperbilirubinemia and high AST and ALT levels (Table 1). Abdominal CT scan showed multiple, different sized and shaped masses, mostly in the right lobe, with the largest one measuring 10x10 cm (Figure 4).With possible diagnosis of an infiltrative lesion or metastasis, a liver biopsy was performed in the local hospital; unfortunately, this was reported to be insufficient because of the presence of extensive necrosis. Repeated biopsy in our center showed extensive necrosis and larval membranes. Review of the previous biopsy showed similar membranes, which had been missed. The patient was put on albendazole therapy before a decision concerning surgery could be made. Now after approximately two months, her abdominal pain has improved, and she has mild icteric sclera, to be followed-up by imaging studies for probable future surgery or liver transplant.


Alveolar echinococcosis of the liver: report of three cases from different geographic areas of iran.

Geramizadeh B, Nikeghbalian S, Malekhosseini SA - Hepat Mon (2012)

CT Scan Shows Well Defined Masses in Right Lobe of the Liver
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475026&req=5

fig366: CT Scan Shows Well Defined Masses in Right Lobe of the Liver
Mentions: Physical examination showed icteric sclera. Heart and lung examination were unremarkable. Abdominal examination showed hepatomegaly. Laboratory findings showed; anemia, hyperbilirubinemia and high AST and ALT levels (Table 1). Abdominal CT scan showed multiple, different sized and shaped masses, mostly in the right lobe, with the largest one measuring 10x10 cm (Figure 4).With possible diagnosis of an infiltrative lesion or metastasis, a liver biopsy was performed in the local hospital; unfortunately, this was reported to be insufficient because of the presence of extensive necrosis. Repeated biopsy in our center showed extensive necrosis and larval membranes. Review of the previous biopsy showed similar membranes, which had been missed. The patient was put on albendazole therapy before a decision concerning surgery could be made. Now after approximately two months, her abdominal pain has improved, and she has mild icteric sclera, to be followed-up by imaging studies for probable future surgery or liver transplant.

Bottom Line: There were three female patients, 21, 47 and 53 year-old.According to our experience, AE is not an uncommon disease in Iran.Moreover, it has a widespread epidemiology, i.e., this disease should be suspected in all provinces of Iran, not only in the northern, but also in the southern regions of the country.

View Article: PubMed Central - PubMed

Affiliation: Transplant Research Center, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran ; Department of Pathology, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran.

ABSTRACT

Introduction: Alveolar echinococcosis (AE) is a chronic, serious and sometimes lethal parasitic infection, which is caused by Echinococcus multilocularis (EM). AE has been reported to occur in people from the north of Iran; however, until now there have been no cases of AE reportedfrom the southern provinces, such as Khuzestan.

Case presentation: Herein, we report our experiences with three cases of hepatic AE, who presented with large masses in the liver, from both the northern and southern provinces of Iran. Three patients are described who were presented with hepatic masses from different provinces of the country.

Conclusions: There were three female patients, 21, 47 and 53 year-old. They were presented with liver masses from different centers of the country i.e. Khorasan, Ardabil and Khuzestan. According to our experience, AE is not an uncommon disease in Iran. Moreover, it has a widespread epidemiology, i.e., this disease should be suspected in all provinces of Iran, not only in the northern, but also in the southern regions of the country.

No MeSH data available.


Related in: MedlinePlus