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Alveolar echinococcosis of the liver: report of three cases from different geographic areas of iran.

Geramizadeh B, Nikeghbalian S, Malekhosseini SA - Hepat Mon (2012)

Bottom Line: There were three female patients, 21, 47 and 53 year-old.According to our experience, AE is not an uncommon disease in Iran.Moreover, it has a widespread epidemiology, i.e., this disease should be suspected in all provinces of Iran, not only in the northern, but also in the southern regions of the country.

View Article: PubMed Central - PubMed

Affiliation: Transplant Research Center, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran ; Department of Pathology, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran.

ABSTRACT

Introduction: Alveolar echinococcosis (AE) is a chronic, serious and sometimes lethal parasitic infection, which is caused by Echinococcus multilocularis (EM). AE has been reported to occur in people from the north of Iran; however, until now there have been no cases of AE reportedfrom the southern provinces, such as Khuzestan.

Case presentation: Herein, we report our experiences with three cases of hepatic AE, who presented with large masses in the liver, from both the northern and southern provinces of Iran. Three patients are described who were presented with hepatic masses from different provinces of the country.

Conclusions: There were three female patients, 21, 47 and 53 year-old. They were presented with liver masses from different centers of the country i.e. Khorasan, Ardabil and Khuzestan. According to our experience, AE is not an uncommon disease in Iran. Moreover, it has a widespread epidemiology, i.e., this disease should be suspected in all provinces of Iran, not only in the northern, but also in the southern regions of the country.

No MeSH data available.


Related in: MedlinePlus

Gross View of the Resected Liver Mass With Tiny Sponge Like Cysts
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fig364: Gross View of the Resected Liver Mass With Tiny Sponge Like Cysts

Mentions: Physical examination showed icteric sclera. Heart and lung examination were unremarkable. Abdominal examination showed mild hepatomegaly. Vital signs were normal. Laboratory findings showed; leukocytosis, hyperbilirubinemia, anemia and high AST, ALT and alkaline phosphatase levels (Table 1).Abdominal CT scan (Figure 1) showed a multiloculated mass in the left lobe of the liver. Liver needle biopsy in the local hospital was reported as the hydatid cyst of Echinococcus granulosus, so with this diagnosis, the patient was operated on and a segment of the liver was resected, this showed a large well-defined mass (20x16x7 cm) with tiny honeycomb like microcystic spaces (Figure 2). Pathologic studies showed complete necrosis, with some larval membranes (Figure 3).With the pathologic diagnosis of alveolar hydatid cyst, albendazole therapy was started. Now, approximately six months after surgery, the patient is doing well and is completely free of metastasis and symptoms.


Alveolar echinococcosis of the liver: report of three cases from different geographic areas of iran.

Geramizadeh B, Nikeghbalian S, Malekhosseini SA - Hepat Mon (2012)

Gross View of the Resected Liver Mass With Tiny Sponge Like Cysts
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475026&req=5

fig364: Gross View of the Resected Liver Mass With Tiny Sponge Like Cysts
Mentions: Physical examination showed icteric sclera. Heart and lung examination were unremarkable. Abdominal examination showed mild hepatomegaly. Vital signs were normal. Laboratory findings showed; leukocytosis, hyperbilirubinemia, anemia and high AST, ALT and alkaline phosphatase levels (Table 1).Abdominal CT scan (Figure 1) showed a multiloculated mass in the left lobe of the liver. Liver needle biopsy in the local hospital was reported as the hydatid cyst of Echinococcus granulosus, so with this diagnosis, the patient was operated on and a segment of the liver was resected, this showed a large well-defined mass (20x16x7 cm) with tiny honeycomb like microcystic spaces (Figure 2). Pathologic studies showed complete necrosis, with some larval membranes (Figure 3).With the pathologic diagnosis of alveolar hydatid cyst, albendazole therapy was started. Now, approximately six months after surgery, the patient is doing well and is completely free of metastasis and symptoms.

Bottom Line: There were three female patients, 21, 47 and 53 year-old.According to our experience, AE is not an uncommon disease in Iran.Moreover, it has a widespread epidemiology, i.e., this disease should be suspected in all provinces of Iran, not only in the northern, but also in the southern regions of the country.

View Article: PubMed Central - PubMed

Affiliation: Transplant Research Center, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran ; Department of Pathology, Department of Pathology, Shiraz University of Medical Science, Shiraz, IR Iran.

ABSTRACT

Introduction: Alveolar echinococcosis (AE) is a chronic, serious and sometimes lethal parasitic infection, which is caused by Echinococcus multilocularis (EM). AE has been reported to occur in people from the north of Iran; however, until now there have been no cases of AE reportedfrom the southern provinces, such as Khuzestan.

Case presentation: Herein, we report our experiences with three cases of hepatic AE, who presented with large masses in the liver, from both the northern and southern provinces of Iran. Three patients are described who were presented with hepatic masses from different provinces of the country.

Conclusions: There were three female patients, 21, 47 and 53 year-old. They were presented with liver masses from different centers of the country i.e. Khorasan, Ardabil and Khuzestan. According to our experience, AE is not an uncommon disease in Iran. Moreover, it has a widespread epidemiology, i.e., this disease should be suspected in all provinces of Iran, not only in the northern, but also in the southern regions of the country.

No MeSH data available.


Related in: MedlinePlus