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Generation of polycyclic aromatic hydrocarbons (PAHs) during woodworking operations.

Bruschweiler ED, Danuser B, Huynh CK, Wild P, Schupfer P, Vernez D, Boiteux P, Hopf NB - Front Oncol (2012)

Bottom Line: Occupational exposures to wood dust have been associated with an elevated risk of sinonasal cancer (SNC).Personal PAH exposures were between 37.5-119.8 ng m(-3) during wood working operations.Our results suggest that PAH exposures are present during woodworking operations and hence could play a role in the mechanism of cancer induction related to wood dust exposure.

View Article: PubMed Central - PubMed

Affiliation: Institute for Work and Health (IST), University of Lausanne Lausanne, Switzerland.

ABSTRACT
Occupational exposures to wood dust have been associated with an elevated risk of sinonasal cancer (SNC). Wood dust is recognized as a human carcinogen but the specific cancer causative agent remains unknown. One possible explanation is a co-exposure to; wood dust and polycyclic aromatic hydrocarbons (PAHs). PAHs could be generated during incomplete combustion of wood due to heat created by use of power tools. To determine if PAHs are generated from wood during common wood working operations, PAH concentrations in wood dust samples collected in an experimental chamber operated under controlled conditions were analyzed. In addition, personal air samples from workers exposed to wood dust (n = 30) were collected. Wood dust was generated using three different power tools: vibrating sander, belt sander, and saw; and six wood materials: fir, Medium Density Fiberboard (MDF), beech, mahogany, oak and wood melamine. Monitoring of wood workers was carried out by means of personal sampler device during wood working operations. We measured 21 PAH concentrations in wood dust samples by capillary gas chromatography-ion trap mass spectrometry (GC-MS). Total PAH concentrations in wood dust varied greatly (0.24-7.95 ppm) with the lowest being in MDF dust and the highest in wood melamine dust. Personal PAH exposures were between 37.5-119.8 ng m(-3) during wood working operations. Our results suggest that PAH exposures are present during woodworking operations and hence could play a role in the mechanism of cancer induction related to wood dust exposure.

No MeSH data available.


Related in: MedlinePlus

Size distribution of wood dust particles in six wood processing factories (modern and traditional) with cut-off sizes according to a multi-stage cascade impactor.
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Figure 4: Size distribution of wood dust particles in six wood processing factories (modern and traditional) with cut-off sizes according to a multi-stage cascade impactor.

Mentions: Total PAH concentrations for wood working operations were in the following descending order: sanding > sawing > others (Table 3). Wood dust particles size distributions by with the cutoff sizes indicated for each fraction for the six wood processing factories are presented graphically (Figure 4). Often the MMAD is used as an indicator of a particle's size in terms of its aerodynamic size. Thereby particles of differing geometric size, shape, and density are compared aerodynamically with the behavior of particles that are unit density (1 g/cm3) spheres. Dust deposits in various regions, and ACGIH has defined the fractions of the airborne particles as inhalable (100 μm cut-point), thoracic (10 μm cut-point), and respirable (4 μm cut-point) (ACGIH, 1994). Wood dust MMAD was measured to 10.15 μm (GSD = 1.53). Wood dust exposures were characterized by predominantly larges particles as already mentioned by Lee et al. (2011). Our results from wood processing factories (n = 6) support Lee et al.'s findings; low respirable dust concentration (25.4%) and high inhalable dust concentration, which corresponded to 65% of total sampled mass.


Generation of polycyclic aromatic hydrocarbons (PAHs) during woodworking operations.

Bruschweiler ED, Danuser B, Huynh CK, Wild P, Schupfer P, Vernez D, Boiteux P, Hopf NB - Front Oncol (2012)

Size distribution of wood dust particles in six wood processing factories (modern and traditional) with cut-off sizes according to a multi-stage cascade impactor.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475003&req=5

Figure 4: Size distribution of wood dust particles in six wood processing factories (modern and traditional) with cut-off sizes according to a multi-stage cascade impactor.
Mentions: Total PAH concentrations for wood working operations were in the following descending order: sanding > sawing > others (Table 3). Wood dust particles size distributions by with the cutoff sizes indicated for each fraction for the six wood processing factories are presented graphically (Figure 4). Often the MMAD is used as an indicator of a particle's size in terms of its aerodynamic size. Thereby particles of differing geometric size, shape, and density are compared aerodynamically with the behavior of particles that are unit density (1 g/cm3) spheres. Dust deposits in various regions, and ACGIH has defined the fractions of the airborne particles as inhalable (100 μm cut-point), thoracic (10 μm cut-point), and respirable (4 μm cut-point) (ACGIH, 1994). Wood dust MMAD was measured to 10.15 μm (GSD = 1.53). Wood dust exposures were characterized by predominantly larges particles as already mentioned by Lee et al. (2011). Our results from wood processing factories (n = 6) support Lee et al.'s findings; low respirable dust concentration (25.4%) and high inhalable dust concentration, which corresponded to 65% of total sampled mass.

Bottom Line: Occupational exposures to wood dust have been associated with an elevated risk of sinonasal cancer (SNC).Personal PAH exposures were between 37.5-119.8 ng m(-3) during wood working operations.Our results suggest that PAH exposures are present during woodworking operations and hence could play a role in the mechanism of cancer induction related to wood dust exposure.

View Article: PubMed Central - PubMed

Affiliation: Institute for Work and Health (IST), University of Lausanne Lausanne, Switzerland.

ABSTRACT
Occupational exposures to wood dust have been associated with an elevated risk of sinonasal cancer (SNC). Wood dust is recognized as a human carcinogen but the specific cancer causative agent remains unknown. One possible explanation is a co-exposure to; wood dust and polycyclic aromatic hydrocarbons (PAHs). PAHs could be generated during incomplete combustion of wood due to heat created by use of power tools. To determine if PAHs are generated from wood during common wood working operations, PAH concentrations in wood dust samples collected in an experimental chamber operated under controlled conditions were analyzed. In addition, personal air samples from workers exposed to wood dust (n = 30) were collected. Wood dust was generated using three different power tools: vibrating sander, belt sander, and saw; and six wood materials: fir, Medium Density Fiberboard (MDF), beech, mahogany, oak and wood melamine. Monitoring of wood workers was carried out by means of personal sampler device during wood working operations. We measured 21 PAH concentrations in wood dust samples by capillary gas chromatography-ion trap mass spectrometry (GC-MS). Total PAH concentrations in wood dust varied greatly (0.24-7.95 ppm) with the lowest being in MDF dust and the highest in wood melamine dust. Personal PAH exposures were between 37.5-119.8 ng m(-3) during wood working operations. Our results suggest that PAH exposures are present during woodworking operations and hence could play a role in the mechanism of cancer induction related to wood dust exposure.

No MeSH data available.


Related in: MedlinePlus