Limits...
Generation of polycyclic aromatic hydrocarbons (PAHs) during woodworking operations.

Bruschweiler ED, Danuser B, Huynh CK, Wild P, Schupfer P, Vernez D, Boiteux P, Hopf NB - Front Oncol (2012)

Bottom Line: Occupational exposures to wood dust have been associated with an elevated risk of sinonasal cancer (SNC).Personal PAH exposures were between 37.5-119.8 ng m(-3) during wood working operations.Our results suggest that PAH exposures are present during woodworking operations and hence could play a role in the mechanism of cancer induction related to wood dust exposure.

View Article: PubMed Central - PubMed

Affiliation: Institute for Work and Health (IST), University of Lausanne Lausanne, Switzerland.

ABSTRACT
Occupational exposures to wood dust have been associated with an elevated risk of sinonasal cancer (SNC). Wood dust is recognized as a human carcinogen but the specific cancer causative agent remains unknown. One possible explanation is a co-exposure to; wood dust and polycyclic aromatic hydrocarbons (PAHs). PAHs could be generated during incomplete combustion of wood due to heat created by use of power tools. To determine if PAHs are generated from wood during common wood working operations, PAH concentrations in wood dust samples collected in an experimental chamber operated under controlled conditions were analyzed. In addition, personal air samples from workers exposed to wood dust (n = 30) were collected. Wood dust was generated using three different power tools: vibrating sander, belt sander, and saw; and six wood materials: fir, Medium Density Fiberboard (MDF), beech, mahogany, oak and wood melamine. Monitoring of wood workers was carried out by means of personal sampler device during wood working operations. We measured 21 PAH concentrations in wood dust samples by capillary gas chromatography-ion trap mass spectrometry (GC-MS). Total PAH concentrations in wood dust varied greatly (0.24-7.95 ppm) with the lowest being in MDF dust and the highest in wood melamine dust. Personal PAH exposures were between 37.5-119.8 ng m(-3) during wood working operations. Our results suggest that PAH exposures are present during woodworking operations and hence could play a role in the mechanism of cancer induction related to wood dust exposure.

No MeSH data available.


Related in: MedlinePlus

Personal inhalable dust concentration (μg/m3) (p-value = 0.38) and BaP concentration (ng/m3) (p-value = 0.004) by factory type.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3475003&req=5

Figure 2: Personal inhalable dust concentration (μg/m3) (p-value = 0.38) and BaP concentration (ng/m3) (p-value = 0.004) by factory type.

Mentions: PAH concentrations in personal inhalable dust samples collected among construction and furniture workers (n = 30) ranged from 37.5 to 119.8 ng m−3 (GM = 67.8 ng m−3 GSD = 1.4). A mixture of wood materials were used in both industries; fir, MDF, spruce, beech, and wood melamine. Table 3 summarizes by factory type and operation, the total PAHs, Σ6PAHs, BaP, and pyrene concentrations (ng m−3), as well as dust concentrations (μg m−3) quantified in the personal samples. Workers classified as “traditional factory workers” (n = 16) had statistically significantly higher (p-value = 0.004) BaP concentrations compared to the “modern furniture industry worker” (n = 14) (Figure 2); while the opposite was true for pyrene with concentrations almost four times higher for the modern factory (Table 3). No difference was detected for total PAHs (p-value = 0.54) and Σ6PAHs (p-value = 0.22).


Generation of polycyclic aromatic hydrocarbons (PAHs) during woodworking operations.

Bruschweiler ED, Danuser B, Huynh CK, Wild P, Schupfer P, Vernez D, Boiteux P, Hopf NB - Front Oncol (2012)

Personal inhalable dust concentration (μg/m3) (p-value = 0.38) and BaP concentration (ng/m3) (p-value = 0.004) by factory type.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3475003&req=5

Figure 2: Personal inhalable dust concentration (μg/m3) (p-value = 0.38) and BaP concentration (ng/m3) (p-value = 0.004) by factory type.
Mentions: PAH concentrations in personal inhalable dust samples collected among construction and furniture workers (n = 30) ranged from 37.5 to 119.8 ng m−3 (GM = 67.8 ng m−3 GSD = 1.4). A mixture of wood materials were used in both industries; fir, MDF, spruce, beech, and wood melamine. Table 3 summarizes by factory type and operation, the total PAHs, Σ6PAHs, BaP, and pyrene concentrations (ng m−3), as well as dust concentrations (μg m−3) quantified in the personal samples. Workers classified as “traditional factory workers” (n = 16) had statistically significantly higher (p-value = 0.004) BaP concentrations compared to the “modern furniture industry worker” (n = 14) (Figure 2); while the opposite was true for pyrene with concentrations almost four times higher for the modern factory (Table 3). No difference was detected for total PAHs (p-value = 0.54) and Σ6PAHs (p-value = 0.22).

Bottom Line: Occupational exposures to wood dust have been associated with an elevated risk of sinonasal cancer (SNC).Personal PAH exposures were between 37.5-119.8 ng m(-3) during wood working operations.Our results suggest that PAH exposures are present during woodworking operations and hence could play a role in the mechanism of cancer induction related to wood dust exposure.

View Article: PubMed Central - PubMed

Affiliation: Institute for Work and Health (IST), University of Lausanne Lausanne, Switzerland.

ABSTRACT
Occupational exposures to wood dust have been associated with an elevated risk of sinonasal cancer (SNC). Wood dust is recognized as a human carcinogen but the specific cancer causative agent remains unknown. One possible explanation is a co-exposure to; wood dust and polycyclic aromatic hydrocarbons (PAHs). PAHs could be generated during incomplete combustion of wood due to heat created by use of power tools. To determine if PAHs are generated from wood during common wood working operations, PAH concentrations in wood dust samples collected in an experimental chamber operated under controlled conditions were analyzed. In addition, personal air samples from workers exposed to wood dust (n = 30) were collected. Wood dust was generated using three different power tools: vibrating sander, belt sander, and saw; and six wood materials: fir, Medium Density Fiberboard (MDF), beech, mahogany, oak and wood melamine. Monitoring of wood workers was carried out by means of personal sampler device during wood working operations. We measured 21 PAH concentrations in wood dust samples by capillary gas chromatography-ion trap mass spectrometry (GC-MS). Total PAH concentrations in wood dust varied greatly (0.24-7.95 ppm) with the lowest being in MDF dust and the highest in wood melamine dust. Personal PAH exposures were between 37.5-119.8 ng m(-3) during wood working operations. Our results suggest that PAH exposures are present during woodworking operations and hence could play a role in the mechanism of cancer induction related to wood dust exposure.

No MeSH data available.


Related in: MedlinePlus