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Outcome of MRI-guided vacuum-assisted breast biopsy - initial experience at Institute of Oncology Ljubljana, Slovenia.

Zebic-Sinkovec M, Hertl K, Kadivec M, Cavlek M, Podobnik G, Snoj M - Radiol Oncol (2012)

Bottom Line: MRI guided procedures (needle biopsy, presurgical localisation) are mandatory for suspicious findings visible only at MRI, with potential influence on therapeutic decision.We evaluated the MRI findings that led to biopsy and we investigated the core and postoperative histology results and follow-up data.The biopsy was technically successful in 14 (93%) of 15 women.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.

ABSTRACT

Background: Like all breast imaging modalities MRI has limited specificity and the positive predictive value for lesions detected by MRI alone ranges between 15 and 50%. MRI guided procedures (needle biopsy, presurgical localisation) are mandatory for suspicious findings visible only at MRI, with potential influence on therapeutic decision. The aim of this retrospective study was to evaluate our initial clinical experience with MRI-guided vacuum-assisted breast biopsy as an alternative to surgical excision and to investigate the outcome of MRI-guided breast biopsy as a function of the MRI features of the lesions. PATIENTS AND METHODS.: In 14 women (median age 51 years) with 14 MRI-detected lesions, MRI-guided vacuum-assisted breast biopsy was performed. We evaluated the MRI findings that led to biopsy and we investigated the core and postoperative histology results and follow-up data.

Results: The biopsy was technically successful in 14 (93%) of 15 women. Of 14 biopsies in 14 women, core histology revealed 6 malignant (6/14, 43%), 6 benign (6/14, 43%) and 2 high-risk (2/14, 14%) lesions. Among the 6 cancer 3 were invasive and 3 were ductal carcinoma in situ (DCIS). The probability of malignancy in our experience was higher for non-mass lesion type and for washout and plateau kinetics.

Conclusions: Our initial experience confirms that MRI-guided vacuum-assisted biopsy is fast, safe and accurate alternative to surgical biopsy for breast lesions detected at MRI only.

No MeSH data available.


Related in: MedlinePlus

A,B. Biopsy coil device. Photographs show a four-channel breast biopsy coil with positioning device (A) and a grid-positioning device (B).
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f1-rado-46-02-97: A,B. Biopsy coil device. Photographs show a four-channel breast biopsy coil with positioning device (A) and a grid-positioning device (B).

Mentions: Among these 6 cancers (Figures 1–6) 3 were invasive cancers (2 invasive lobular carcinoma and 1 invasive tubular carcinoma) and other 3 were DCIS (1 massive DCIS with foci of well differentiated invasive carcinoma). Three of 6 cancers were found in women with personal history of breast carcinoma. The median size of the MRI lesions in these 6 cancers was 2.6 cm (range 0.8–6.0 cm). MRI-guided vacuum-assisted biopsy revealed 2 high-risk lesions, in one case there was atypical ductal hyperplasia and in other papilloma. Papilloma was operated on and was proved to be benign.


Outcome of MRI-guided vacuum-assisted breast biopsy - initial experience at Institute of Oncology Ljubljana, Slovenia.

Zebic-Sinkovec M, Hertl K, Kadivec M, Cavlek M, Podobnik G, Snoj M - Radiol Oncol (2012)

A,B. Biopsy coil device. Photographs show a four-channel breast biopsy coil with positioning device (A) and a grid-positioning device (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3472934&req=5

f1-rado-46-02-97: A,B. Biopsy coil device. Photographs show a four-channel breast biopsy coil with positioning device (A) and a grid-positioning device (B).
Mentions: Among these 6 cancers (Figures 1–6) 3 were invasive cancers (2 invasive lobular carcinoma and 1 invasive tubular carcinoma) and other 3 were DCIS (1 massive DCIS with foci of well differentiated invasive carcinoma). Three of 6 cancers were found in women with personal history of breast carcinoma. The median size of the MRI lesions in these 6 cancers was 2.6 cm (range 0.8–6.0 cm). MRI-guided vacuum-assisted biopsy revealed 2 high-risk lesions, in one case there was atypical ductal hyperplasia and in other papilloma. Papilloma was operated on and was proved to be benign.

Bottom Line: MRI guided procedures (needle biopsy, presurgical localisation) are mandatory for suspicious findings visible only at MRI, with potential influence on therapeutic decision.We evaluated the MRI findings that led to biopsy and we investigated the core and postoperative histology results and follow-up data.The biopsy was technically successful in 14 (93%) of 15 women.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.

ABSTRACT

Background: Like all breast imaging modalities MRI has limited specificity and the positive predictive value for lesions detected by MRI alone ranges between 15 and 50%. MRI guided procedures (needle biopsy, presurgical localisation) are mandatory for suspicious findings visible only at MRI, with potential influence on therapeutic decision. The aim of this retrospective study was to evaluate our initial clinical experience with MRI-guided vacuum-assisted breast biopsy as an alternative to surgical excision and to investigate the outcome of MRI-guided breast biopsy as a function of the MRI features of the lesions. PATIENTS AND METHODS.: In 14 women (median age 51 years) with 14 MRI-detected lesions, MRI-guided vacuum-assisted breast biopsy was performed. We evaluated the MRI findings that led to biopsy and we investigated the core and postoperative histology results and follow-up data.

Results: The biopsy was technically successful in 14 (93%) of 15 women. Of 14 biopsies in 14 women, core histology revealed 6 malignant (6/14, 43%), 6 benign (6/14, 43%) and 2 high-risk (2/14, 14%) lesions. Among the 6 cancer 3 were invasive and 3 were ductal carcinoma in situ (DCIS). The probability of malignancy in our experience was higher for non-mass lesion type and for washout and plateau kinetics.

Conclusions: Our initial experience confirms that MRI-guided vacuum-assisted biopsy is fast, safe and accurate alternative to surgical biopsy for breast lesions detected at MRI only.

No MeSH data available.


Related in: MedlinePlus