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A multi-parameter decoupling method with a Lamb wave sensor for improving the selectivity of label-free liquid detection.

Zhou L, Wu Y, Xuan M, Manceau JF, Bastien F - Sensors (Basel) (2012)

Bottom Line: We found they can play very different roles in the detections.Here, the A(0) mode is used to identify the density of the detected liquid and with this density value we obtained the viscosity by the amplitude shifts of the S(0) mode.This could be a way to distinguish an unknown liquid with high sensitivity or to solve the problem of selectivity of label-free detection on biosensors.

View Article: PubMed Central - PubMed

Affiliation: Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. zhoulq@sibet.ac.cn

ABSTRACT
In this paper, a liquid multi-parameter decoupling method with only one Lamb wave sensor is presented. In a Lamb wave sensor, antisymmetric modes (A(01) mode for low frequency, A(03) mode for high frequency) and symmetric modes (S(0) mode) are used to detect multiple parameters of a liquid, such as its density, sound velocity, and viscosity. We found they can play very different roles in the detections. For example, the A(01) mode is very sensitive to the liquid's density but the A(03) mode is sensitive to the sound velocity. Here, the A(0) mode is used to identify the density of the detected liquid and with this density value we obtained the viscosity by the amplitude shifts of the S(0) mode. This could be a way to distinguish an unknown liquid with high sensitivity or to solve the problem of selectivity of label-free detection on biosensors.

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Related in: MedlinePlus

The responses of the S0 mode to different concentrations of NaBr solutions.
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f4-sensors-12-10369: The responses of the S0 mode to different concentrations of NaBr solutions.

Mentions: The responses of the S0 mode to the solutions of NaBr are similar to the ones of NaCl (Figure 3), the central frequency does not show apparent shifts due to their changing concentrations. However, the changes of the amplitude are related to the liquid's concentrations (Figure 4). It is because the frequency is mainly affected by the liquid density and sound velocity, which has no effects on the real part of the phase velocity of S0 mode (Equation (6)) [40]. The amplitude of the S0 mode in NaBr solution (Figure 4) shows that energy losses increase with the concentration, which is caused by the density and the viscosity of the liquid (Equation (7)). This can be used to decouple the density and the viscosity of the solution.


A multi-parameter decoupling method with a Lamb wave sensor for improving the selectivity of label-free liquid detection.

Zhou L, Wu Y, Xuan M, Manceau JF, Bastien F - Sensors (Basel) (2012)

The responses of the S0 mode to different concentrations of NaBr solutions.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3472832&req=5

f4-sensors-12-10369: The responses of the S0 mode to different concentrations of NaBr solutions.
Mentions: The responses of the S0 mode to the solutions of NaBr are similar to the ones of NaCl (Figure 3), the central frequency does not show apparent shifts due to their changing concentrations. However, the changes of the amplitude are related to the liquid's concentrations (Figure 4). It is because the frequency is mainly affected by the liquid density and sound velocity, which has no effects on the real part of the phase velocity of S0 mode (Equation (6)) [40]. The amplitude of the S0 mode in NaBr solution (Figure 4) shows that energy losses increase with the concentration, which is caused by the density and the viscosity of the liquid (Equation (7)). This can be used to decouple the density and the viscosity of the solution.

Bottom Line: We found they can play very different roles in the detections.Here, the A(0) mode is used to identify the density of the detected liquid and with this density value we obtained the viscosity by the amplitude shifts of the S(0) mode.This could be a way to distinguish an unknown liquid with high sensitivity or to solve the problem of selectivity of label-free detection on biosensors.

View Article: PubMed Central - PubMed

Affiliation: Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China. zhoulq@sibet.ac.cn

ABSTRACT
In this paper, a liquid multi-parameter decoupling method with only one Lamb wave sensor is presented. In a Lamb wave sensor, antisymmetric modes (A(01) mode for low frequency, A(03) mode for high frequency) and symmetric modes (S(0) mode) are used to detect multiple parameters of a liquid, such as its density, sound velocity, and viscosity. We found they can play very different roles in the detections. For example, the A(01) mode is very sensitive to the liquid's density but the A(03) mode is sensitive to the sound velocity. Here, the A(0) mode is used to identify the density of the detected liquid and with this density value we obtained the viscosity by the amplitude shifts of the S(0) mode. This could be a way to distinguish an unknown liquid with high sensitivity or to solve the problem of selectivity of label-free detection on biosensors.

Show MeSH
Related in: MedlinePlus