Limits...
Ultrasound-assisted extraction of carnosic acid and rosmarinic acid using ionic liquid solution from Rosmarinus officinalis.

Zu G, Zhang R, Yang L, Ma C, Zu Y, Wang W, Zhao C - Int J Mol Sci (2012)

Bottom Line: Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis.Ultrasound extraction parameters, including soaking time, solid-liquid ratio, ultrasound power and time, and the number of extraction cycles, were discussed by single factor experiments and the main influence factors were optimized by response surface methodology.The proposed approach was demonstrated as having higher efficiency, shorter extraction time and as a new alternative for the extraction of carnosic acid and rosmarinic acid from R. officinalis compared with traditional reference extraction methods.

View Article: PubMed Central - PubMed

Affiliation: State Engineering Laboratory for Bioresource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; E-Mails: zygenefu@163.com (G.Z.); zhangrongrui1986@126.com (R.Z.); mchmchmchmch@163.com (C.M.); wjwang225@hotmail.com (W.W.); zcjsj@163.com (C.Z.).

ABSTRACT
Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis. Eight ionic liquids, with different cations and anions, were investigated in this work and [C(8)mim]Br was selected as the optimal solvent. Ultrasound extraction parameters, including soaking time, solid-liquid ratio, ultrasound power and time, and the number of extraction cycles, were discussed by single factor experiments and the main influence factors were optimized by response surface methodology. The proposed approach was demonstrated as having higher efficiency, shorter extraction time and as a new alternative for the extraction of carnosic acid and rosmarinic acid from R. officinalis compared with traditional reference extraction methods. Ionic liquids are considered to be green solvents, in the ultrasound-assisted extraction of key chemicals from medicinal plants, and show great potential.

Show MeSH
Response surface plots showing the effects of variables on average extraction efficiency of target compounds. (a) Interaction of solid-liquid ratio and ultrasound time; (b) Interaction of ultrasound power and solid-liquid ratio; (c) Interaction of ultrasound power and time. The average extraction efficiency is expressed as the observed values of target compounds and the maximum amount in each curve was taken to be 100%.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
getmorefigures.php?uid=PMC3472728&req=5

f3-ijms-13-11027: Response surface plots showing the effects of variables on average extraction efficiency of target compounds. (a) Interaction of solid-liquid ratio and ultrasound time; (b) Interaction of ultrasound power and solid-liquid ratio; (c) Interaction of ultrasound power and time. The average extraction efficiency is expressed as the observed values of target compounds and the maximum amount in each curve was taken to be 100%.

Mentions: The response surfaces for the effect of independent variables on average extraction efficiency of carnosic acid and rosmarinic acid were showed in Figure 3. Figure 3a–c presented the interaction of ultrasound time and solid–liquid ratio, ultrasound power and solid–liquid ratio, ultrasound power and ultrasound time, respectively.


Ultrasound-assisted extraction of carnosic acid and rosmarinic acid using ionic liquid solution from Rosmarinus officinalis.

Zu G, Zhang R, Yang L, Ma C, Zu Y, Wang W, Zhao C - Int J Mol Sci (2012)

Response surface plots showing the effects of variables on average extraction efficiency of target compounds. (a) Interaction of solid-liquid ratio and ultrasound time; (b) Interaction of ultrasound power and solid-liquid ratio; (c) Interaction of ultrasound power and time. The average extraction efficiency is expressed as the observed values of target compounds and the maximum amount in each curve was taken to be 100%.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC3472728&req=5

f3-ijms-13-11027: Response surface plots showing the effects of variables on average extraction efficiency of target compounds. (a) Interaction of solid-liquid ratio and ultrasound time; (b) Interaction of ultrasound power and solid-liquid ratio; (c) Interaction of ultrasound power and time. The average extraction efficiency is expressed as the observed values of target compounds and the maximum amount in each curve was taken to be 100%.
Mentions: The response surfaces for the effect of independent variables on average extraction efficiency of carnosic acid and rosmarinic acid were showed in Figure 3. Figure 3a–c presented the interaction of ultrasound time and solid–liquid ratio, ultrasound power and solid–liquid ratio, ultrasound power and ultrasound time, respectively.

Bottom Line: Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis.Ultrasound extraction parameters, including soaking time, solid-liquid ratio, ultrasound power and time, and the number of extraction cycles, were discussed by single factor experiments and the main influence factors were optimized by response surface methodology.The proposed approach was demonstrated as having higher efficiency, shorter extraction time and as a new alternative for the extraction of carnosic acid and rosmarinic acid from R. officinalis compared with traditional reference extraction methods.

View Article: PubMed Central - PubMed

Affiliation: State Engineering Laboratory for Bioresource Eco-Utilization, Northeast Forestry University, Harbin 150040, China; E-Mails: zygenefu@163.com (G.Z.); zhangrongrui1986@126.com (R.Z.); mchmchmchmch@163.com (C.M.); wjwang225@hotmail.com (W.W.); zcjsj@163.com (C.Z.).

ABSTRACT
Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis. Eight ionic liquids, with different cations and anions, were investigated in this work and [C(8)mim]Br was selected as the optimal solvent. Ultrasound extraction parameters, including soaking time, solid-liquid ratio, ultrasound power and time, and the number of extraction cycles, were discussed by single factor experiments and the main influence factors were optimized by response surface methodology. The proposed approach was demonstrated as having higher efficiency, shorter extraction time and as a new alternative for the extraction of carnosic acid and rosmarinic acid from R. officinalis compared with traditional reference extraction methods. Ionic liquids are considered to be green solvents, in the ultrasound-assisted extraction of key chemicals from medicinal plants, and show great potential.

Show MeSH