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Solitary extramedullary plasmacytoma of the thyroid gland.

Ridal M, Ouattassi N, Harmouch T, Amarti A, Alami MN - Case Rep Otolaryngol (2012)

Bottom Line: We present a case of an extramedullary nonmucosal plasmacytoma of the thyroid gland which is the first case with regional metastatic lymph nodes.Although localized forms management is still controversial, authors require combined approach for regional metastatic forms.The prognosis is favorable compared to solitary bone plasmacytomas or multiple myeloma.

View Article: PubMed Central - PubMed

Affiliation: ENT Head and Neck Surgery Department, Hassan II University Hospital, Fez 30000, Morocco.

ABSTRACT
Solitary extramedullary plasmacytoma of the thyroid gland is an uncommon condition. Up to date, its clinical pathological features are not fully understood. We present a case of an extramedullary nonmucosal plasmacytoma of the thyroid gland which is the first case with regional metastatic lymph nodes. This condition requires a scrupulous survey to rule out a metastatic multiple myeloma. Although localized forms management is still controversial, authors require combined approach for regional metastatic forms. The prognosis is favorable compared to solitary bone plasmacytomas or multiple myeloma.

No MeSH data available.


Related in: MedlinePlus

Intense and widespread staining of CD79A (a) and CD 138 (b), Ki 67 very low<10% (c).
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fig3: Intense and widespread staining of CD79A (a) and CD 138 (b), Ki 67 very low<10% (c).

Mentions: The patient underwent a left lobo-isthmectomy with excision of the lymph node. The frozen section examination of the thyroid and the lymph node specimens returned for a lymphomatous process. However, the final pathological examination showed infiltration of thyroid tissue by well-differentiated plasma cells with some immature cells with cytonuclear atypia and high mitotic index (Figures 2 and 3).


Solitary extramedullary plasmacytoma of the thyroid gland.

Ridal M, Ouattassi N, Harmouch T, Amarti A, Alami MN - Case Rep Otolaryngol (2012)

Intense and widespread staining of CD79A (a) and CD 138 (b), Ki 67 very low<10% (c).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3472536&req=5

fig3: Intense and widespread staining of CD79A (a) and CD 138 (b), Ki 67 very low<10% (c).
Mentions: The patient underwent a left lobo-isthmectomy with excision of the lymph node. The frozen section examination of the thyroid and the lymph node specimens returned for a lymphomatous process. However, the final pathological examination showed infiltration of thyroid tissue by well-differentiated plasma cells with some immature cells with cytonuclear atypia and high mitotic index (Figures 2 and 3).

Bottom Line: We present a case of an extramedullary nonmucosal plasmacytoma of the thyroid gland which is the first case with regional metastatic lymph nodes.Although localized forms management is still controversial, authors require combined approach for regional metastatic forms.The prognosis is favorable compared to solitary bone plasmacytomas or multiple myeloma.

View Article: PubMed Central - PubMed

Affiliation: ENT Head and Neck Surgery Department, Hassan II University Hospital, Fez 30000, Morocco.

ABSTRACT
Solitary extramedullary plasmacytoma of the thyroid gland is an uncommon condition. Up to date, its clinical pathological features are not fully understood. We present a case of an extramedullary nonmucosal plasmacytoma of the thyroid gland which is the first case with regional metastatic lymph nodes. This condition requires a scrupulous survey to rule out a metastatic multiple myeloma. Although localized forms management is still controversial, authors require combined approach for regional metastatic forms. The prognosis is favorable compared to solitary bone plasmacytomas or multiple myeloma.

No MeSH data available.


Related in: MedlinePlus