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Setting an agenda for comparative effectiveness systematic reviews in CKD care.

Crews DC, Greer RC, Fadrowski JJ, Choi MJ, Doggett D, Segal JB, Fawole KA, Crawford PR, Boulware LE - BMC Nephrol (2012)

Bottom Line: We engaged stakeholders in the chronic kidney disease community to prioritize topics for future comparative effectiveness research systematic reviews.We developed a preliminary list of suggested topics and stakeholders refined and ranked topics based on their importance.Among 46 topics identified, stakeholders nominated 18 as 'high' priority.

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ABSTRACT
Systematic reviews comparing the effectiveness of strategies to prevent, detect, and treat chronic kidney disease are needed to inform patient care. We engaged stakeholders in the chronic kidney disease community to prioritize topics for future comparative effectiveness research systematic reviews. We developed a preliminary list of suggested topics and stakeholders refined and ranked topics based on their importance. Among 46 topics identified, stakeholders nominated 18 as 'high' priority. Most pertained to strategies to slow disease progression, including: (a) treat proteinuria, (b) improve access to care, (c) treat hypertension, (d) use health information technology, and (e) implement dietary strategies. Most (15 of 18) topics had been previously studied with two or more randomized controlled trials, indicating feasibility of rigorous systematic reviews. Chronic kidney disease topics rated by stakeholders as 'high priority' are varied in scope and may lead to quality systematic reviews impacting practice and policy.

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Chronic Kidney Disease Comparative Effectiveness Research (CER) Topic Identification Process.
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Figure 1: Chronic Kidney Disease Comparative Effectiveness Research (CER) Topic Identification Process.

Mentions: We established a preliminary protocol for identifying and prioritizing topics, which we later revised with input from the stakeholders. The protocol consisted of three main activities: (1) identifying and categorizing potential topics of interest to the CKD community for systematic review and primary CER studies, (2) asking stakeholders to rank topics that would be of greatest interest to the CKD community, and (3) exploring the feasibility of performing CER systematic reviews on these high priority topics (Figure 1).


Setting an agenda for comparative effectiveness systematic reviews in CKD care.

Crews DC, Greer RC, Fadrowski JJ, Choi MJ, Doggett D, Segal JB, Fawole KA, Crawford PR, Boulware LE - BMC Nephrol (2012)

Chronic Kidney Disease Comparative Effectiveness Research (CER) Topic Identification Process.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3472164&req=5

Figure 1: Chronic Kidney Disease Comparative Effectiveness Research (CER) Topic Identification Process.
Mentions: We established a preliminary protocol for identifying and prioritizing topics, which we later revised with input from the stakeholders. The protocol consisted of three main activities: (1) identifying and categorizing potential topics of interest to the CKD community for systematic review and primary CER studies, (2) asking stakeholders to rank topics that would be of greatest interest to the CKD community, and (3) exploring the feasibility of performing CER systematic reviews on these high priority topics (Figure 1).

Bottom Line: We engaged stakeholders in the chronic kidney disease community to prioritize topics for future comparative effectiveness research systematic reviews.We developed a preliminary list of suggested topics and stakeholders refined and ranked topics based on their importance.Among 46 topics identified, stakeholders nominated 18 as 'high' priority.

View Article: PubMed Central - HTML - PubMed

ABSTRACT
Systematic reviews comparing the effectiveness of strategies to prevent, detect, and treat chronic kidney disease are needed to inform patient care. We engaged stakeholders in the chronic kidney disease community to prioritize topics for future comparative effectiveness research systematic reviews. We developed a preliminary list of suggested topics and stakeholders refined and ranked topics based on their importance. Among 46 topics identified, stakeholders nominated 18 as 'high' priority. Most pertained to strategies to slow disease progression, including: (a) treat proteinuria, (b) improve access to care, (c) treat hypertension, (d) use health information technology, and (e) implement dietary strategies. Most (15 of 18) topics had been previously studied with two or more randomized controlled trials, indicating feasibility of rigorous systematic reviews. Chronic kidney disease topics rated by stakeholders as 'high priority' are varied in scope and may lead to quality systematic reviews impacting practice and policy.

Show MeSH
Related in: MedlinePlus