Stepping stones in DNA sequencing.
Bottom Line: In recent years there have been tremendous advances in our ability to rapidly and cost-effectively sequence DNA.However, recent announcements in nanopore sequencing hold the promise of removing this read-length limitation, enabling sequencing of larger intact DNA fragments.This review covers some of the technical advances in sequencing that have opened up new frontiers in genomics.
Affiliation: Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden. email@example.comShow MeSH
Related in: MedlinePlus
Mentions: The most commonly used DNA sequencing technologies, and their challenges and limitations, are described below. A summary table of the features of each technology is provided in Table 1 while the number of sequence reads and read lengths are shown in Fig. 1.
Affiliation: Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden. firstname.lastname@example.org