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Intraoral superficial angiomyxoma of the upper alveolus: report of a unique case.

S V R, Raju MS, J D S, Taneja N, Chandra S, Mahajan S, Panwar E - Case Rep Med (2012)

Bottom Line: Angiomyxomas are relatively a group of uncommon myxoid mesenchymal tumors characterized by frequent local recurrences and show lack of malignant potential.Basically three types of angiomyxomas are recognized superficial, aggressive, and angiomyofibroblastoma.Though the angiomyxomas are rarely reported in the head and neck region, the paper shows reported cases intraorally in the buccal mucosa and floor of the mouth.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Teerthanker Mahaveer Institute of Dental Sciences and Research Centre, Teerthanker Mahaveer University, Bagarpur, Delhi Road, Moradabad 244001, India.

ABSTRACT
Angiomyxomas are relatively a group of uncommon myxoid mesenchymal tumors characterized by frequent local recurrences and show lack of malignant potential. Basically three types of angiomyxomas are recognized superficial, aggressive, and angiomyofibroblastoma. Though the angiomyxomas are rarely reported in the head and neck region, the paper shows reported cases intraorally in the buccal mucosa and floor of the mouth. Here, the authors report a rare case of angiomyxoma presenting as a growth in the upper posterior alveolar mucosa.

No MeSH data available.


Related in: MedlinePlus

The endothelial cells of the blood vessels stained strongly for CD34 (10x).
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fig5: The endothelial cells of the blood vessels stained strongly for CD34 (10x).

Mentions: A 30-year-old male patient presented with a slow-growing, soft mass in the right upper posterior alveolar region, present since 2 years and which was associated with mild pain upon eating (Figure 1). Patient had noticed a mobile tooth in the same region about a year and a half back and had got it extracted. The swelling had continued to grow slowly after the extraction. His medical history was noncontributory. Examination showed that the lesion was diffuse, reddish, slightly ulcerated, and measuring about 3 × 3 cm in size. It was rubbery to firm in consistency and mildly tender, with slight bleeding on palpation. Radiographs were taken but no changes were observed. Incisional biopsy was performed. Microscopic examination revealed epithelium overlying loose myxoid stroma accompanied by a prominent vasculature (Figure 2). Myxoid stroma showed a scattered spindle to stellate-shaped cells which had distinct borders and oval nuclei. There was no cellular or nuclear atypia or hyperchromasia and mitotic activity and necrosis were not present. Small, thin-walled curvilinear blood vessels were prominent throughout the stroma. A mild inflammatory infiltrate was present predominantly neutrophils (Figure 3). An immunohistochemical staining was performed using vimentin and CD34 antigens. Most of the stromal tumor cells were immunopositive for vimentin (Figure 4) and the endothelial cells of the blood vessels displayed immunoreactivity for CD34 (Figure 5). This confirmed the diagnosis of superficial angiomyxomas. Treatment was not done due to patient unwillingness.


Intraoral superficial angiomyxoma of the upper alveolus: report of a unique case.

S V R, Raju MS, J D S, Taneja N, Chandra S, Mahajan S, Panwar E - Case Rep Med (2012)

The endothelial cells of the blood vessels stained strongly for CD34 (10x).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3420143&req=5

fig5: The endothelial cells of the blood vessels stained strongly for CD34 (10x).
Mentions: A 30-year-old male patient presented with a slow-growing, soft mass in the right upper posterior alveolar region, present since 2 years and which was associated with mild pain upon eating (Figure 1). Patient had noticed a mobile tooth in the same region about a year and a half back and had got it extracted. The swelling had continued to grow slowly after the extraction. His medical history was noncontributory. Examination showed that the lesion was diffuse, reddish, slightly ulcerated, and measuring about 3 × 3 cm in size. It was rubbery to firm in consistency and mildly tender, with slight bleeding on palpation. Radiographs were taken but no changes were observed. Incisional biopsy was performed. Microscopic examination revealed epithelium overlying loose myxoid stroma accompanied by a prominent vasculature (Figure 2). Myxoid stroma showed a scattered spindle to stellate-shaped cells which had distinct borders and oval nuclei. There was no cellular or nuclear atypia or hyperchromasia and mitotic activity and necrosis were not present. Small, thin-walled curvilinear blood vessels were prominent throughout the stroma. A mild inflammatory infiltrate was present predominantly neutrophils (Figure 3). An immunohistochemical staining was performed using vimentin and CD34 antigens. Most of the stromal tumor cells were immunopositive for vimentin (Figure 4) and the endothelial cells of the blood vessels displayed immunoreactivity for CD34 (Figure 5). This confirmed the diagnosis of superficial angiomyxomas. Treatment was not done due to patient unwillingness.

Bottom Line: Angiomyxomas are relatively a group of uncommon myxoid mesenchymal tumors characterized by frequent local recurrences and show lack of malignant potential.Basically three types of angiomyxomas are recognized superficial, aggressive, and angiomyofibroblastoma.Though the angiomyxomas are rarely reported in the head and neck region, the paper shows reported cases intraorally in the buccal mucosa and floor of the mouth.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Teerthanker Mahaveer Institute of Dental Sciences and Research Centre, Teerthanker Mahaveer University, Bagarpur, Delhi Road, Moradabad 244001, India.

ABSTRACT
Angiomyxomas are relatively a group of uncommon myxoid mesenchymal tumors characterized by frequent local recurrences and show lack of malignant potential. Basically three types of angiomyxomas are recognized superficial, aggressive, and angiomyofibroblastoma. Though the angiomyxomas are rarely reported in the head and neck region, the paper shows reported cases intraorally in the buccal mucosa and floor of the mouth. Here, the authors report a rare case of angiomyxoma presenting as a growth in the upper posterior alveolar mucosa.

No MeSH data available.


Related in: MedlinePlus