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Promoting predictive, preventive and personalised medicine: European event of global importance.

Golubnitschaja O, Swanton C, Danesi R, Costigliola V - EPMA J (2011)

View Article: PubMed Central - PubMed

Affiliation: The "European Association for Predictive, Preventive and Personalised Medicine", Brussels, Belgium ; Department of Radiology, University of Bonn, Bonn, Germany.

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As has already reported, in 2010 the EU-Commission has triggered consultations with the leading experts who are actively developing innovative bio/medical technologies and promoting the field of personalised medicine... From April till June 2010, the series of workshops was signed and organised by the EU-Commission as the “Vision 2020” in Brussels aiming to elaborate the items which will be fundamental to develop personalised medicine for us—European citizens in the new frame-programme Common Strategic Framework (also known as FP-8) during the next 10–15 years beginning with 2013... Therefore, in healthcare we need to develop a new culture among experts in order to promote the multidisciplinary field of personalised medicine... In order to promote innovative educational programmes, in collaboration with Springer, EPMA has developed worldwide pioneer initiatives creating the didactic materials for the field as follows: that regularly updates both needs and achievements in the field of PPPM in application to major and rare pathologies The book-series (Book-series Editor: Olga Golubnitschaja; the book-series release is starting in 2012 with the following volumes (one of the volumes is given in the Fig.  2): “Healthcare Overview: New Perspectives”, Volume Editor: Vincenzo Costigliola, Brussels, Belgium “PPPM in Diabetes mellitus”, Volume Editor: Mahmood Mozaffari, Augusta, USA “PPPM in Neurodegenerative diseases”, Volume Editor: Silvia Mandel, Haifa, Israel “Drug delivery systems: Advanced technologies potentially applicable in personalised medicine”, Volume Editor: Jorge Coelho, Coimbra, Portugal... The reader will find a number of positive examples in this journal-issue concordant with this statement... Hence, the prevalence of birth asphyxia (the most frequent pathology in newborns) registered for children born to educated mothers is several times lower compared with those born to uneducated / illiterate mothers... New European guidelines should be elaborated emphasising advanced diagnostics approaches for reproductive medicine, healthcare of children and youth... Our message is—new European guidelines should create the robust juristic and economic platform for advanced medical services utilising the cost-effective models of risk assessment followed by tailored treatments focussed on the precursor stages of chronic disease... It is increasingly recognised that personalised medicine is essential to identify those patients most likely to benefit from novel therapeutic approaches and importantly, identify those patients likely to derive harm from a new intervention... The identification of predictive biomarkers of response to conventional and novel therapeutics is of paramount importance to minimise serious adverse events associated with treatment and maximise the proportion of patients who will derive therapeutic benefit... Without innovation in healthcare such developments will pose a serious threat to health economies and may lead to collapsing healthcare system... By contrast, the effective utilisation of advanced early/predictive diagnostics together with preventive and personalised medical approaches could enable a significant portion of the population to reach their senior years in vibrant psychosocial health, with excellent physical and mental wellbeing, participating actively in society... The strategic developments will be, further, discussed at the EPMA-World Congress 2011 in Bonn (Fig. 6)... Everybody, who is interested in and contributing to the field is very welcome to actively participate in our meeting!

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Related in: MedlinePlus

Worldwide prevalence of diabetes mellitus with getting more pessimistic prognosis for the next 3 decades: current literature updates
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Fig5: Worldwide prevalence of diabetes mellitus with getting more pessimistic prognosis for the next 3 decades: current literature updates

Mentions: As a consequence of the accumulating clinical data and knowledge about the epidemiology and pathological mechanisms of the most frequent causes of morbidity and mortality, we are currently reconsidering our view of the origins and progression of cardiovascular, oncologic and neurodegenerative diseases. The majority of these pathologies are of chronic nature: they progress from precursor lesions over one or even several decades of life until a diagnosis is made that is often too late for effective therapeutic intervention. An excellent example is the epidemic scale of diabetes mellitus type 2 witnessed in the European Union. In most industrialised countries and countries with large populations, the permanently growing cohort of diabetics creates a serious healthcare problem and dramatic health economic burden. Estimates for diabetes prevalence in the years 2030 is half a billion patients worldwide—see Fig. 5.Fig. 5


Promoting predictive, preventive and personalised medicine: European event of global importance.

Golubnitschaja O, Swanton C, Danesi R, Costigliola V - EPMA J (2011)

Worldwide prevalence of diabetes mellitus with getting more pessimistic prognosis for the next 3 decades: current literature updates
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3405384&req=5

Fig5: Worldwide prevalence of diabetes mellitus with getting more pessimistic prognosis for the next 3 decades: current literature updates
Mentions: As a consequence of the accumulating clinical data and knowledge about the epidemiology and pathological mechanisms of the most frequent causes of morbidity and mortality, we are currently reconsidering our view of the origins and progression of cardiovascular, oncologic and neurodegenerative diseases. The majority of these pathologies are of chronic nature: they progress from precursor lesions over one or even several decades of life until a diagnosis is made that is often too late for effective therapeutic intervention. An excellent example is the epidemic scale of diabetes mellitus type 2 witnessed in the European Union. In most industrialised countries and countries with large populations, the permanently growing cohort of diabetics creates a serious healthcare problem and dramatic health economic burden. Estimates for diabetes prevalence in the years 2030 is half a billion patients worldwide—see Fig. 5.Fig. 5

View Article: PubMed Central - PubMed

Affiliation: The "European Association for Predictive, Preventive and Personalised Medicine", Brussels, Belgium ; Department of Radiology, University of Bonn, Bonn, Germany.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

As has already reported, in 2010 the EU-Commission has triggered consultations with the leading experts who are actively developing innovative bio/medical technologies and promoting the field of personalised medicine... From April till June 2010, the series of workshops was signed and organised by the EU-Commission as the “Vision 2020” in Brussels aiming to elaborate the items which will be fundamental to develop personalised medicine for us—European citizens in the new frame-programme Common Strategic Framework (also known as FP-8) during the next 10–15 years beginning with 2013... Therefore, in healthcare we need to develop a new culture among experts in order to promote the multidisciplinary field of personalised medicine... In order to promote innovative educational programmes, in collaboration with Springer, EPMA has developed worldwide pioneer initiatives creating the didactic materials for the field as follows: that regularly updates both needs and achievements in the field of PPPM in application to major and rare pathologies The book-series (Book-series Editor: Olga Golubnitschaja; the book-series release is starting in 2012 with the following volumes (one of the volumes is given in the Fig.  2): “Healthcare Overview: New Perspectives”, Volume Editor: Vincenzo Costigliola, Brussels, Belgium “PPPM in Diabetes mellitus”, Volume Editor: Mahmood Mozaffari, Augusta, USA “PPPM in Neurodegenerative diseases”, Volume Editor: Silvia Mandel, Haifa, Israel “Drug delivery systems: Advanced technologies potentially applicable in personalised medicine”, Volume Editor: Jorge Coelho, Coimbra, Portugal... The reader will find a number of positive examples in this journal-issue concordant with this statement... Hence, the prevalence of birth asphyxia (the most frequent pathology in newborns) registered for children born to educated mothers is several times lower compared with those born to uneducated / illiterate mothers... New European guidelines should be elaborated emphasising advanced diagnostics approaches for reproductive medicine, healthcare of children and youth... Our message is—new European guidelines should create the robust juristic and economic platform for advanced medical services utilising the cost-effective models of risk assessment followed by tailored treatments focussed on the precursor stages of chronic disease... It is increasingly recognised that personalised medicine is essential to identify those patients most likely to benefit from novel therapeutic approaches and importantly, identify those patients likely to derive harm from a new intervention... The identification of predictive biomarkers of response to conventional and novel therapeutics is of paramount importance to minimise serious adverse events associated with treatment and maximise the proportion of patients who will derive therapeutic benefit... Without innovation in healthcare such developments will pose a serious threat to health economies and may lead to collapsing healthcare system... By contrast, the effective utilisation of advanced early/predictive diagnostics together with preventive and personalised medical approaches could enable a significant portion of the population to reach their senior years in vibrant psychosocial health, with excellent physical and mental wellbeing, participating actively in society... The strategic developments will be, further, discussed at the EPMA-World Congress 2011 in Bonn (Fig. 6)... Everybody, who is interested in and contributing to the field is very welcome to actively participate in our meeting!

No MeSH data available.


Related in: MedlinePlus