Limits...
Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report.

Karunarathne S, Weerasinghe S, Govindapala D, Fernando H, Jayaratne B - Thromb J (2012)

Bottom Line: A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure.Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection.Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication.

View Article: PubMed Central - HTML - PubMed

Affiliation: National Hospital of Sri Lanka, Regent Street, Colombo, Sri Lanka. suneth871@gmail.com.

ABSTRACT
A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication. Management of secondary cold agglutinin disease is mainly supportive.

No MeSH data available.


Related in: MedlinePlus

Dry gangrene of fingertips involving nine out of the ten fingers.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3403954&req=5

Figure 1: Dry gangrene of fingertips involving nine out of the ten fingers.

Mentions: On examination he was febrile and sweaty. He appeared ill but was not in pain. He had severe pallor and was mildly icteric. There was no finger clubbing. Fingers, toes and forefoot were discolored, shrunken and appeared lifeless (Figures1 and 2). Pulse rate was 92bpm, regular with good volume. Jugular venous pressure was not elevated. Blood pressure was 110/70mmHg. On auscultation heart was in dual rhythm with an ejection systolic murmur in aortic area. All peripheral pulses were palpable. Respiratory system examination was normal. No palpable liver, spleen or other masses were detected on abdominal examination. Patient was conscious and rational. No neurological deficits were detected except absent sensation on peripheries which were discoloured.


Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report.

Karunarathne S, Weerasinghe S, Govindapala D, Fernando H, Jayaratne B - Thromb J (2012)

Dry gangrene of fingertips involving nine out of the ten fingers.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3403954&req=5

Figure 1: Dry gangrene of fingertips involving nine out of the ten fingers.
Mentions: On examination he was febrile and sweaty. He appeared ill but was not in pain. He had severe pallor and was mildly icteric. There was no finger clubbing. Fingers, toes and forefoot were discolored, shrunken and appeared lifeless (Figures1 and 2). Pulse rate was 92bpm, regular with good volume. Jugular venous pressure was not elevated. Blood pressure was 110/70mmHg. On auscultation heart was in dual rhythm with an ejection systolic murmur in aortic area. All peripheral pulses were palpable. Respiratory system examination was normal. No palpable liver, spleen or other masses were detected on abdominal examination. Patient was conscious and rational. No neurological deficits were detected except absent sensation on peripheries which were discoloured.

Bottom Line: A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure.Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection.Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication.

View Article: PubMed Central - HTML - PubMed

Affiliation: National Hospital of Sri Lanka, Regent Street, Colombo, Sri Lanka. suneth871@gmail.com.

ABSTRACT
A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication. Management of secondary cold agglutinin disease is mainly supportive.

No MeSH data available.


Related in: MedlinePlus