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Effect of active immunization against GnRH on testosterone concentration, libido and sperm quality in mature AI boars.

Bilskis R, Sutkeviciene N, Riskeviciene V, Januskauskas A, Zilinskas H - Acta Vet. Scand. (2012)

Bottom Line: The aim of the present study was to investigate the efficacy of the Improvac on testosterone concentration in blood serum, sexual behavior and sperm quality in matured AI boars.A total of nine Danish Landrace AI boars were included in the analysis.Testosterone concentration correlated with libido (r = 0.531; p < 0.001), volume of ejaculate (r = 0.324; p < 0.001) and the percentage of morphologically normal spermatozoa (r = 0.207; p < 0.05).

View Article: PubMed Central - HTML - PubMed

Affiliation: Veterinary Academy of Lithuanian University of Health Sciences, Tilzes str, 18, LT-47181, Kaunas, Lithuania.

ABSTRACT

Background: The aim of the present study was to investigate the efficacy of the Improvac on testosterone concentration in blood serum, sexual behavior and sperm quality in matured AI boars. A total of nine Danish Landrace AI boars were included in the analysis.

Methods: The trial period lasted for 15 weeks and was divided into four periods: Control period: three weeks before vaccination; Period I - four weeks after first vaccination; Period II - four weeks after second vaccination, Period III - four weeks after third vaccination. Blood and sperm samples were collected at weekly intervals. Freshly collected sperm samples were analyzed.

Results: Testosterone concentration correlated with libido (r = 0.531; p < 0.001), volume of ejaculate (r = 0.324; p < 0.001) and the percentage of morphologically normal spermatozoa (r = 0.207; p < 0.05). Testosterone concentration rised significantly (p < 0.05) in 5-6 week of trial, e. i. after the first dose of Improvac and after this peak the level of testosterone further progressively decreased (p < 0.05).

Conclusions: Results from this study indicate that active immunization of sexually matured boars against GnRH has negative impact on testosterone concentration, sexual behavior, volume of ejaculate and total number of normal spermatozoa in ejaculate.

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Dynamics of testosterone concentration during the entire experimental period. N = 9 animals. Arrows indicate the vaccination dates.
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Figure 1: Dynamics of testosterone concentration during the entire experimental period. N = 9 animals. Arrows indicate the vaccination dates.

Mentions: The testosterone concentration was steady in control group, but rised significantly in all animals after the first vaccination (p < 0.05) injection. Then, after this peak the level of testosterone further progressively decreased. Dynamics of testosterone levels in the blood serum of experimental boars during trial showed in Figure 1.


Effect of active immunization against GnRH on testosterone concentration, libido and sperm quality in mature AI boars.

Bilskis R, Sutkeviciene N, Riskeviciene V, Januskauskas A, Zilinskas H - Acta Vet. Scand. (2012)

Dynamics of testosterone concentration during the entire experimental period. N = 9 animals. Arrows indicate the vaccination dates.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3403930&req=5

Figure 1: Dynamics of testosterone concentration during the entire experimental period. N = 9 animals. Arrows indicate the vaccination dates.
Mentions: The testosterone concentration was steady in control group, but rised significantly in all animals after the first vaccination (p < 0.05) injection. Then, after this peak the level of testosterone further progressively decreased. Dynamics of testosterone levels in the blood serum of experimental boars during trial showed in Figure 1.

Bottom Line: The aim of the present study was to investigate the efficacy of the Improvac on testosterone concentration in blood serum, sexual behavior and sperm quality in matured AI boars.A total of nine Danish Landrace AI boars were included in the analysis.Testosterone concentration correlated with libido (r = 0.531; p < 0.001), volume of ejaculate (r = 0.324; p < 0.001) and the percentage of morphologically normal spermatozoa (r = 0.207; p < 0.05).

View Article: PubMed Central - HTML - PubMed

Affiliation: Veterinary Academy of Lithuanian University of Health Sciences, Tilzes str, 18, LT-47181, Kaunas, Lithuania.

ABSTRACT

Background: The aim of the present study was to investigate the efficacy of the Improvac on testosterone concentration in blood serum, sexual behavior and sperm quality in matured AI boars. A total of nine Danish Landrace AI boars were included in the analysis.

Methods: The trial period lasted for 15 weeks and was divided into four periods: Control period: three weeks before vaccination; Period I - four weeks after first vaccination; Period II - four weeks after second vaccination, Period III - four weeks after third vaccination. Blood and sperm samples were collected at weekly intervals. Freshly collected sperm samples were analyzed.

Results: Testosterone concentration correlated with libido (r = 0.531; p < 0.001), volume of ejaculate (r = 0.324; p < 0.001) and the percentage of morphologically normal spermatozoa (r = 0.207; p < 0.05). Testosterone concentration rised significantly (p < 0.05) in 5-6 week of trial, e. i. after the first dose of Improvac and after this peak the level of testosterone further progressively decreased (p < 0.05).

Conclusions: Results from this study indicate that active immunization of sexually matured boars against GnRH has negative impact on testosterone concentration, sexual behavior, volume of ejaculate and total number of normal spermatozoa in ejaculate.

Show MeSH