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Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration.

Singh P, Saggar K, Kaur M, Pannu DS - J Pediatr Neurosci (2012)

Bottom Line: Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia.On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus.This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

ABSTRACT
Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia. On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus. This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance.

No MeSH data available.


Related in: MedlinePlus

T2* weighted image showing hypointensity with a central region of hyperintensity in the medial globus pallidus (eye-of-the-tiger sign)
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Figure 4: T2* weighted image showing hypointensity with a central region of hyperintensity in the medial globus pallidus (eye-of-the-tiger sign)


Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration.

Singh P, Saggar K, Kaur M, Pannu DS - J Pediatr Neurosci (2012)

T2* weighted image showing hypointensity with a central region of hyperintensity in the medial globus pallidus (eye-of-the-tiger sign)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3401648&req=5

Figure 4: T2* weighted image showing hypointensity with a central region of hyperintensity in the medial globus pallidus (eye-of-the-tiger sign)
Bottom Line: Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia.On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus.This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiodiagnosis, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

ABSTRACT
Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia. On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus. This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance.

No MeSH data available.


Related in: MedlinePlus