Immunological impact of an additional early measles vaccine in Gambian children: responses to a boost at 3 years.
Bottom Line: T-cell effector and memory responses using IFN-γ ELIspot and cytokine assays and antibody titres using a haemagglutination-inhibition assay were compared at various times.At 36 months of age group 2 antibody titres exceeded protective levels but were 4-fold lower than group 1; effector and cytokine responses were similar.Cellular responses after 9 months were generally insignificantly different.
Affiliation: Medical Research Council Laboratories, Banjul, Gambia.Show MeSH
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Affiliation: Medical Research Council Laboratories, Banjul, Gambia.