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Acute bronchiolitis in a paediatric emergency department of Northern Greece. Comparisons between two decades.

Sakellaropoulou A, Emporiadou M, Aivazis V, Mauromixalis J, Hatzistilianou M - Arch Med Sci (2012)

Bottom Line: There was a predominance of male sex in both decades (p = 0.509).There was a statistically significant difference (p < 0.001) concerning the use of nebulised salbutamol with nebulised ipratropium between the two decades.Finally, during 2001-2002, the use of bronchodilators with or without corticosteroids was more frequent and it appears to be correlated with the reduced number of admissions to hospital (p < 0.05) compared with 1990-1991.

View Article: PubMed Central - PubMed

Affiliation: 2 Paediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece.

ABSTRACT

Introduction: Acute bronchiolitis is the most common lower respiratory tract infection in infants and toddlers concerning small bronchi or bronchioli. This retrospective study aimed to evaluate the incidence of acute bronchiolitis and the use of β(2)-agonists between two different decades.

Material and methods: During 1990-1991 and 2001-2002, the files of the 2(nd) Paediatric Emergency Department of Aristotle University of Thessaloniki, AHEPA Hospital were reviewed and cases of acute bronchiolitis were recorded and analysed.

Results: During 1990-1991, 14 538 children were identified with respiratory infections and bronchiolitis was diagnosed in 519/14 538 children (3.56%). Only 34 out of 519 patients received nebulised salbutamol (6.6%) and 221/519 were hospitalized (42.6%). During 2001-2002, 9001 children were found to have respiratory tract infections and acute bronchiolitis was diagnosed in 641/9001 of them (7.12%). In total, 411/641 children (64.1%) received salbutamol and ipratropium, and 89/641 patients (13.88%) were hospitalized. There was a predominance of male sex in both decades (p = 0.509). There was a statistically significant difference (p < 0.001) concerning the use of nebulised salbutamol with nebulised ipratropium between the two decades. Finally, during 2001-2002, the use of bronchodilators with or without corticosteroids was more frequent and it appears to be correlated with the reduced number of admissions to hospital (p < 0.05) compared with 1990-1991.

Conclusions: There was an increase in the incidence of acute bronchiolitis during the last decade. The admission rate decreased probably due to the use of nebulized salbutamol and ipratropium, but further multicentre comparative trials are required to define the role of bronchodilators in the treatment of acute bronchiolitis.

No MeSH data available.


Related in: MedlinePlus

Monthly distribution of patients with acute bronchiolitis during the years 1990-1991 and 2001-2002
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Figure 0001: Monthly distribution of patients with acute bronchiolitis during the years 1990-1991 and 2001-2002

Mentions: Acute bronchiolitis is considered to be the most common viral infection of the lower airways in infants. Acute bronchiolitis occurs in epidemics in the winter months. In tropical and subtropical climates, these epidemics occur during the rainy season [6]. In our study, the majority of cases were observed during spring and winter (Figure 1).


Acute bronchiolitis in a paediatric emergency department of Northern Greece. Comparisons between two decades.

Sakellaropoulou A, Emporiadou M, Aivazis V, Mauromixalis J, Hatzistilianou M - Arch Med Sci (2012)

Monthly distribution of patients with acute bronchiolitis during the years 1990-1991 and 2001-2002
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3400904&req=5

Figure 0001: Monthly distribution of patients with acute bronchiolitis during the years 1990-1991 and 2001-2002
Mentions: Acute bronchiolitis is considered to be the most common viral infection of the lower airways in infants. Acute bronchiolitis occurs in epidemics in the winter months. In tropical and subtropical climates, these epidemics occur during the rainy season [6]. In our study, the majority of cases were observed during spring and winter (Figure 1).

Bottom Line: There was a predominance of male sex in both decades (p = 0.509).There was a statistically significant difference (p < 0.001) concerning the use of nebulised salbutamol with nebulised ipratropium between the two decades.Finally, during 2001-2002, the use of bronchodilators with or without corticosteroids was more frequent and it appears to be correlated with the reduced number of admissions to hospital (p < 0.05) compared with 1990-1991.

View Article: PubMed Central - PubMed

Affiliation: 2 Paediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece.

ABSTRACT

Introduction: Acute bronchiolitis is the most common lower respiratory tract infection in infants and toddlers concerning small bronchi or bronchioli. This retrospective study aimed to evaluate the incidence of acute bronchiolitis and the use of β(2)-agonists between two different decades.

Material and methods: During 1990-1991 and 2001-2002, the files of the 2(nd) Paediatric Emergency Department of Aristotle University of Thessaloniki, AHEPA Hospital were reviewed and cases of acute bronchiolitis were recorded and analysed.

Results: During 1990-1991, 14 538 children were identified with respiratory infections and bronchiolitis was diagnosed in 519/14 538 children (3.56%). Only 34 out of 519 patients received nebulised salbutamol (6.6%) and 221/519 were hospitalized (42.6%). During 2001-2002, 9001 children were found to have respiratory tract infections and acute bronchiolitis was diagnosed in 641/9001 of them (7.12%). In total, 411/641 children (64.1%) received salbutamol and ipratropium, and 89/641 patients (13.88%) were hospitalized. There was a predominance of male sex in both decades (p = 0.509). There was a statistically significant difference (p < 0.001) concerning the use of nebulised salbutamol with nebulised ipratropium between the two decades. Finally, during 2001-2002, the use of bronchodilators with or without corticosteroids was more frequent and it appears to be correlated with the reduced number of admissions to hospital (p < 0.05) compared with 1990-1991.

Conclusions: There was an increase in the incidence of acute bronchiolitis during the last decade. The admission rate decreased probably due to the use of nebulized salbutamol and ipratropium, but further multicentre comparative trials are required to define the role of bronchodilators in the treatment of acute bronchiolitis.

No MeSH data available.


Related in: MedlinePlus