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Methyl (R)-2-(2-chloro-phen-yl)-2-(3-nitro-phenyl-sulfon-yloxy)acetate.
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The reaction between methyl (R)-2-(2-chloro-phen-yl)-2-hy-droxy-acetate and 3-nitro-benzene-sulfonyl chloride gave the title compound, C(15)H(12)ClNO(7)S, which is a promising inter-mediate for the synthesis of Clopidrogel, an anti-platelet drug used in the prevention of strokes and heart attacks.In the crystal, mol-ecules are linked through C-H⋯O interactions, and there is also a short Cl⋯O contact present [Cl⋯O = 3.018 (2) Å].
Affiliation: Department of Materials and Chemical Engineering, Zhongyuan University of Technology, Zhengzhou, Henan 450007, People's Republic of China.
ABSTRACT
The reaction between methyl (R)-2-(2-chloro-phen-yl)-2-hy-droxy-acetate and 3-nitro-benzene-sulfonyl chloride gave the title compound, C(15)H(12)ClNO(7)S, which is a promising inter-mediate for the synthesis of Clopidrogel, an anti-platelet drug used in the prevention of strokes and heart attacks. In the crystal, mol-ecules are linked through C-H⋯O interactions, and there is also a short Cl⋯O contact present [Cl⋯O = 3.018 (2) Å]. No MeSH data available. Related in: MedlinePlus |
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Fap1: A view of the compound with the atomic numbering scheme. Displacement ellipsoids are drawn at the 30% probability level. |
View Article: PubMed Central - HTML - PubMed
Affiliation: Department of Materials and Chemical Engineering, Zhongyuan University of Technology, Zhengzhou, Henan 450007, People's Republic of China.
No MeSH data available.
