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Methyl (R)-2-(2-chloro-phen-yl)-2-(3-nitro-phenyl-sulfon-yloxy)acetate.

Li YH, Xu HW, Zhang LX - Acta Crystallogr Sect E Struct Rep Online (2012)

Bottom Line: The reaction between methyl (R)-2-(2-chloro-phen-yl)-2-hy-droxy-acetate and 3-nitro-benzene-sulfonyl chloride gave the title compound, C(15)H(12)ClNO(7)S, which is a promising inter-mediate for the synthesis of Clopidrogel, an anti-platelet drug used in the prevention of strokes and heart attacks.In the crystal, mol-ecules are linked through C-H⋯O interactions, and there is also a short Cl⋯O contact present [Cl⋯O = 3.018 (2) Å].

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Materials and Chemical Engineering, Zhongyuan University of Technology, Zhengzhou, Henan 450007, People's Republic of China.

ABSTRACT
The reaction between methyl (R)-2-(2-chloro-phen-yl)-2-hy-droxy-acetate and 3-nitro-benzene-sulfonyl chloride gave the title compound, C(15)H(12)ClNO(7)S, which is a promising inter-mediate for the synthesis of Clopidrogel, an anti-platelet drug used in the prevention of strokes and heart attacks. In the crystal, mol-ecules are linked through C-H⋯O interactions, and there is also a short Cl⋯O contact present [Cl⋯O = 3.018 (2) Å].

No MeSH data available.


Related in: MedlinePlus

A view of the compound with the atomic numbering scheme. Displacement ellipsoids are drawn at the 30% probability level.
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Fap1: A view of the compound with the atomic numbering scheme. Displacement ellipsoids are drawn at the 30% probability level.


Methyl (R)-2-(2-chloro-phen-yl)-2-(3-nitro-phenyl-sulfon-yloxy)acetate.

Li YH, Xu HW, Zhang LX - Acta Crystallogr Sect E Struct Rep Online (2012)

A view of the compound with the atomic numbering scheme. Displacement ellipsoids are drawn at the 30% probability level.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3379285&req=5

Fap1: A view of the compound with the atomic numbering scheme. Displacement ellipsoids are drawn at the 30% probability level.
Bottom Line: The reaction between methyl (R)-2-(2-chloro-phen-yl)-2-hy-droxy-acetate and 3-nitro-benzene-sulfonyl chloride gave the title compound, C(15)H(12)ClNO(7)S, which is a promising inter-mediate for the synthesis of Clopidrogel, an anti-platelet drug used in the prevention of strokes and heart attacks.In the crystal, mol-ecules are linked through C-H⋯O interactions, and there is also a short Cl⋯O contact present [Cl⋯O = 3.018 (2) Å].

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Materials and Chemical Engineering, Zhongyuan University of Technology, Zhengzhou, Henan 450007, People's Republic of China.

ABSTRACT
The reaction between methyl (R)-2-(2-chloro-phen-yl)-2-hy-droxy-acetate and 3-nitro-benzene-sulfonyl chloride gave the title compound, C(15)H(12)ClNO(7)S, which is a promising inter-mediate for the synthesis of Clopidrogel, an anti-platelet drug used in the prevention of strokes and heart attacks. In the crystal, mol-ecules are linked through C-H⋯O interactions, and there is also a short Cl⋯O contact present [Cl⋯O = 3.018 (2) Å].

No MeSH data available.


Related in: MedlinePlus