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Primary hyperparathyroidism in older people: surgical treatment with minimally invasive approaches and outcome.

Dobrinja C, Silvestri M, de Manzini N - Int J Endocrinol (2012)

Bottom Line: Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies.Conclusions.Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

View Article: PubMed Central - PubMed

Affiliation: Division of General Surgery, Department of Medical and Surgical Sciences, Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy.

ABSTRACT
Introduction. Elderly patients with primary hyperparathyroidism (pHPT) are often not referred to surgery because of their associated comorbidities that may increase surgical risk. The aim of the study was to review indications and results of minimally invasive approach parathyroidectomy in elderly patients to evaluate its impact on outcome. Materials and Methods. All patients of 70 years of age or older undergoing minimally approach parathyroidectomy at our Department from May 2005 to May 2011 were reviewed. Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies. Results and Discussion. 37 patients were analysed. The average length of stay was 2.8 days. 11 patients were discharged within 24 hours after their operation. Morbidity included 6 transient symptomatic postoperative hypocalcemias while one patient developed a transient laryngeal nerve palsy. Time elapsed from pHPT diagnosis to first surgical visit evidences that the elderly patients were referred after their disease had progressed. Conclusions. Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

No MeSH data available.


Related in: MedlinePlus

Box plot regarding age and sex. The figure shows the distribution by age, represented vertically, and gender, horizontally, of pHPT in our elderly cohort The box plot highlights that, over 5 years of activity of our Department, there was a major incidence of pHPT in females than males (28 versus 9) and that the age of onset of disease was lower in elderly females than elderly males. In fact, for females, the median age was 74 years and lower and upper-quartiles of age ranged from 73 to 77 years; 3 outlier patients 84, 85, and 86 years old at time of operation. On the other side, for males: the median age was 78 years and lower and upper quartiles of age ranged from 76 to 79 years.
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fig2: Box plot regarding age and sex. The figure shows the distribution by age, represented vertically, and gender, horizontally, of pHPT in our elderly cohort The box plot highlights that, over 5 years of activity of our Department, there was a major incidence of pHPT in females than males (28 versus 9) and that the age of onset of disease was lower in elderly females than elderly males. In fact, for females, the median age was 74 years and lower and upper-quartiles of age ranged from 73 to 77 years; 3 outlier patients 84, 85, and 86 years old at time of operation. On the other side, for males: the median age was 78 years and lower and upper quartiles of age ranged from 76 to 79 years.

Mentions: The population's ages were forced with two box plots display (Figures 1 and 2) to show graphically the distribution of elderly population. Figure 1 shows all elderly patients in relation to age while Figure 2 represents the differences between elderly males and elderly females regarding age.


Primary hyperparathyroidism in older people: surgical treatment with minimally invasive approaches and outcome.

Dobrinja C, Silvestri M, de Manzini N - Int J Endocrinol (2012)

Box plot regarding age and sex. The figure shows the distribution by age, represented vertically, and gender, horizontally, of pHPT in our elderly cohort The box plot highlights that, over 5 years of activity of our Department, there was a major incidence of pHPT in females than males (28 versus 9) and that the age of onset of disease was lower in elderly females than elderly males. In fact, for females, the median age was 74 years and lower and upper-quartiles of age ranged from 73 to 77 years; 3 outlier patients 84, 85, and 86 years old at time of operation. On the other side, for males: the median age was 78 years and lower and upper quartiles of age ranged from 76 to 79 years.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3379162&req=5

fig2: Box plot regarding age and sex. The figure shows the distribution by age, represented vertically, and gender, horizontally, of pHPT in our elderly cohort The box plot highlights that, over 5 years of activity of our Department, there was a major incidence of pHPT in females than males (28 versus 9) and that the age of onset of disease was lower in elderly females than elderly males. In fact, for females, the median age was 74 years and lower and upper-quartiles of age ranged from 73 to 77 years; 3 outlier patients 84, 85, and 86 years old at time of operation. On the other side, for males: the median age was 78 years and lower and upper quartiles of age ranged from 76 to 79 years.
Mentions: The population's ages were forced with two box plots display (Figures 1 and 2) to show graphically the distribution of elderly population. Figure 1 shows all elderly patients in relation to age while Figure 2 represents the differences between elderly males and elderly females regarding age.

Bottom Line: Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies.Conclusions.Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

View Article: PubMed Central - PubMed

Affiliation: Division of General Surgery, Department of Medical and Surgical Sciences, Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy.

ABSTRACT
Introduction. Elderly patients with primary hyperparathyroidism (pHPT) are often not referred to surgery because of their associated comorbidities that may increase surgical risk. The aim of the study was to review indications and results of minimally invasive approach parathyroidectomy in elderly patients to evaluate its impact on outcome. Materials and Methods. All patients of 70 years of age or older undergoing minimally approach parathyroidectomy at our Department from May 2005 to May 2011 were reviewed. Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies. Results and Discussion. 37 patients were analysed. The average length of stay was 2.8 days. 11 patients were discharged within 24 hours after their operation. Morbidity included 6 transient symptomatic postoperative hypocalcemias while one patient developed a transient laryngeal nerve palsy. Time elapsed from pHPT diagnosis to first surgical visit evidences that the elderly patients were referred after their disease had progressed. Conclusions. Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

No MeSH data available.


Related in: MedlinePlus