Limits...
Primary hyperparathyroidism in older people: surgical treatment with minimally invasive approaches and outcome.

Dobrinja C, Silvestri M, de Manzini N - Int J Endocrinol (2012)

Bottom Line: Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies.Conclusions.Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

View Article: PubMed Central - PubMed

Affiliation: Division of General Surgery, Department of Medical and Surgical Sciences, Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy.

ABSTRACT
Introduction. Elderly patients with primary hyperparathyroidism (pHPT) are often not referred to surgery because of their associated comorbidities that may increase surgical risk. The aim of the study was to review indications and results of minimally invasive approach parathyroidectomy in elderly patients to evaluate its impact on outcome. Materials and Methods. All patients of 70 years of age or older undergoing minimally approach parathyroidectomy at our Department from May 2005 to May 2011 were reviewed. Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies. Results and Discussion. 37 patients were analysed. The average length of stay was 2.8 days. 11 patients were discharged within 24 hours after their operation. Morbidity included 6 transient symptomatic postoperative hypocalcemias while one patient developed a transient laryngeal nerve palsy. Time elapsed from pHPT diagnosis to first surgical visit evidences that the elderly patients were referred after their disease had progressed. Conclusions. Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

No MeSH data available.


Related in: MedlinePlus

Box plot regarding age. It represents the distribution by age of pHPT in our elderly cohort made up of 37 patients during the last 5 years of activity of the Department of General Surgery of University of Trieste. Elderly mean age at time of operation was 76.08 years (range: 70–86 years). The median age was 75 years and corresponds to the dark thickened band near the middle in the box plot, drawn vertically. The box in the figure shows the lower and upper quartiles of age (range 73–78 years) while whiskers show values below the 25th (from 70 to 72 years) and above the 75th (from 79 to 85 years). The upper dot not included between the whiskers means a patient 86 years old at time of operation.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3379162&req=5

fig1: Box plot regarding age. It represents the distribution by age of pHPT in our elderly cohort made up of 37 patients during the last 5 years of activity of the Department of General Surgery of University of Trieste. Elderly mean age at time of operation was 76.08 years (range: 70–86 years). The median age was 75 years and corresponds to the dark thickened band near the middle in the box plot, drawn vertically. The box in the figure shows the lower and upper quartiles of age (range 73–78 years) while whiskers show values below the 25th (from 70 to 72 years) and above the 75th (from 79 to 85 years). The upper dot not included between the whiskers means a patient 86 years old at time of operation.

Mentions: The population's ages were forced with two box plots display (Figures 1 and 2) to show graphically the distribution of elderly population. Figure 1 shows all elderly patients in relation to age while Figure 2 represents the differences between elderly males and elderly females regarding age.


Primary hyperparathyroidism in older people: surgical treatment with minimally invasive approaches and outcome.

Dobrinja C, Silvestri M, de Manzini N - Int J Endocrinol (2012)

Box plot regarding age. It represents the distribution by age of pHPT in our elderly cohort made up of 37 patients during the last 5 years of activity of the Department of General Surgery of University of Trieste. Elderly mean age at time of operation was 76.08 years (range: 70–86 years). The median age was 75 years and corresponds to the dark thickened band near the middle in the box plot, drawn vertically. The box in the figure shows the lower and upper quartiles of age (range 73–78 years) while whiskers show values below the 25th (from 70 to 72 years) and above the 75th (from 79 to 85 years). The upper dot not included between the whiskers means a patient 86 years old at time of operation.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3379162&req=5

fig1: Box plot regarding age. It represents the distribution by age of pHPT in our elderly cohort made up of 37 patients during the last 5 years of activity of the Department of General Surgery of University of Trieste. Elderly mean age at time of operation was 76.08 years (range: 70–86 years). The median age was 75 years and corresponds to the dark thickened band near the middle in the box plot, drawn vertically. The box in the figure shows the lower and upper quartiles of age (range 73–78 years) while whiskers show values below the 25th (from 70 to 72 years) and above the 75th (from 79 to 85 years). The upper dot not included between the whiskers means a patient 86 years old at time of operation.
Mentions: The population's ages were forced with two box plots display (Figures 1 and 2) to show graphically the distribution of elderly population. Figure 1 shows all elderly patients in relation to age while Figure 2 represents the differences between elderly males and elderly females regarding age.

Bottom Line: Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies.Conclusions.Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

View Article: PubMed Central - PubMed

Affiliation: Division of General Surgery, Department of Medical and Surgical Sciences, Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy.

ABSTRACT
Introduction. Elderly patients with primary hyperparathyroidism (pHPT) are often not referred to surgery because of their associated comorbidities that may increase surgical risk. The aim of the study was to review indications and results of minimally invasive approach parathyroidectomy in elderly patients to evaluate its impact on outcome. Materials and Methods. All patients of 70 years of age or older undergoing minimally approach parathyroidectomy at our Department from May 2005 to May 2011 were reviewed. Data collected included patients demographic information, biochemical pathology, time elapsed from pHPT diagnosis to surgical intervention, operative findings, complications, and results of postoperative biochemical studies. Results and Discussion. 37 patients were analysed. The average length of stay was 2.8 days. 11 patients were discharged within 24 hours after their operation. Morbidity included 6 transient symptomatic postoperative hypocalcemias while one patient developed a transient laryngeal nerve palsy. Time elapsed from pHPT diagnosis to first surgical visit evidences that the elderly patients were referred after their disease had progressed. Conclusions. Our data show that minimally invasive approach to parathyroid surgery seems to be safe and curative also in elderly patients with few associated risks because of combination of modern preoperative imaging, advances in surgical technique, and advances in anesthesia care.

No MeSH data available.


Related in: MedlinePlus