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Morphometric classification and spatial organization of spiral ganglion neurons in the human cochlea: consequences for single fiber response to electrical stimulation.

Potrusil T, Wenger C, Glueckert R, Schrott-Fischer A, Rattay F - Neuroscience (2012)

Bottom Line: Results show that temporal parameters of the spiking pattern are affected by the size of the cell body.Cathodic stimulation was found to induce stronger variations of spikes while also leading to the lowest thresholds and longest latencies.Therefore, anodic stimulation leads to a more uniform excitation profile among SGCs with different cell body size.

View Article: PubMed Central - PubMed

Affiliation: Innsbruck Medical University, Department of Otorhinolaryngology, Laboratory for Inner Ear Biology, Anichstrasse 35, Innsbruck, Austria.

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Threshold currents of E3 and E4 as function of soma diameter for all detected cells. The black E3 axis on the left is half of the grey E4 axis on the right. Corresponding threshold curves have the same color. For better visualization, the markers display a selection of evaluations.
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f0035: Threshold currents of E3 and E4 as function of soma diameter for all detected cells. The black E3 axis on the left is half of the grey E4 axis on the right. Corresponding threshold curves have the same color. For better visualization, the markers display a selection of evaluations.

Mentions: Due to the phase duration ratio of 100 μs to 50 μs, the monophasic threshold currents for both electrode positions are approximately half the values of their biphasic counterparts, as can be seen in Fig. 7.


Morphometric classification and spatial organization of spiral ganglion neurons in the human cochlea: consequences for single fiber response to electrical stimulation.

Potrusil T, Wenger C, Glueckert R, Schrott-Fischer A, Rattay F - Neuroscience (2012)

Threshold currents of E3 and E4 as function of soma diameter for all detected cells. The black E3 axis on the left is half of the grey E4 axis on the right. Corresponding threshold curves have the same color. For better visualization, the markers display a selection of evaluations.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3377987&req=5

f0035: Threshold currents of E3 and E4 as function of soma diameter for all detected cells. The black E3 axis on the left is half of the grey E4 axis on the right. Corresponding threshold curves have the same color. For better visualization, the markers display a selection of evaluations.
Mentions: Due to the phase duration ratio of 100 μs to 50 μs, the monophasic threshold currents for both electrode positions are approximately half the values of their biphasic counterparts, as can be seen in Fig. 7.

Bottom Line: Results show that temporal parameters of the spiking pattern are affected by the size of the cell body.Cathodic stimulation was found to induce stronger variations of spikes while also leading to the lowest thresholds and longest latencies.Therefore, anodic stimulation leads to a more uniform excitation profile among SGCs with different cell body size.

View Article: PubMed Central - PubMed

Affiliation: Innsbruck Medical University, Department of Otorhinolaryngology, Laboratory for Inner Ear Biology, Anichstrasse 35, Innsbruck, Austria.

Show MeSH
Related in: MedlinePlus